Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              18    1135
NP_005913                                                              18    1135
XP_005267046                                                           18    1135
XP_005267045                                                           18    1135
NP_000684                                                              17    2528
NP_001094064                                                           17    3301
NP_060189                                                              17    3301
XP_005265303                                                           17    3301
XP_005265302                                                           17    3301
NP_001138747                                                           17    4312
NP_001138748                                                           17    4312
NP_003401                                                              17    4312
NP_003402                                                              17    4312
NP_001171555                                                           17    4312
NP_001171556                                                           17    4312
XP_005262628                                                           17    4312
XP_006724936                                                           17    4312
XP_005262627                                                           17    4312
XP_005274651                                                           17    4312
XP_006724578                                                           17    4312
XP_005274649                                                           17    4312
XP_005274648                                                           17    4312
XP_006724577                                                           17    4312
XP_006724576                                                           17    4312
NP_001171557                                                           17    4312
NP_277052                                                              15    9605
NP_000287                                                              15    9605
NP_001009944                                                           15    9605
NP_001123910                                                           15    9605
NP_003118                                                              15    9605
NP_001182461                                                           15    9605
NP_009029                                                              15    9605
NP_001826                                                              15    9605
NP_059344                                                              15    9605
NP_006331                                                              15    9605
NP_059345                                                              15    9605
XP_006726693                                                           15    9605
XP_006724391                                                           15    9605
XP_005261338                                                           15    9605
XP_005277858                                                           15    9605
XP_006724390                                                           15    9605
XP_006724389                                                           15    9605
XP_005277857                                                           15    9605
XP_005257005                                                           15    9605
XP_006721701                                                           15    9605
XP_006721700                                                           15    9605
XP_005257002                                                           15    9605
XP_005257001                                                           15    9605
XP_006721699                                                           15    9605
XP_006721698                                                           15    9605
XP_005257000                                                           15    9605
XP_006720958                                                           15    9605
XP_006720957                                                           15    9605
XP_006720956                                                           15    9605
XP_006720955                                                           15    9605
XP_006720954                                                           15    9605
XP_006720953                                                           15    9605
XP_006720952                                                           15    9605
XP_006717317                                                           15    9605
XP_006717316                                                           15    9605
XP_006717315                                                           15    9605
XP_006717314                                                           15    9605
XP_006717313                                                           15    9605
XP_006717312                                                           15    9605
XP_006717311                                                           15    9605
XP_006717310                                                           15    9605
XP_006717309                                                           15    9605
XP_006717308                                                           15    9605
NP_001138360                                                           15    9605
>NP_006715
          Length = 1558

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           R ASRSNLK
Sbjct: 106 RPASRSNLK 114
>NP_005913
          Length = 1608

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           R ASRSNLK
Sbjct: 106 RPASRSNLK 114
>XP_005267046
          Length = 1554

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           R ASRSNLK
Sbjct: 106 RPASRSNLK 114
>XP_005267045
          Length = 1604

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           R ASRSNLK
Sbjct: 106 RPASRSNLK 114
>NP_000684
          Length = 512

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SASRSNLK 9
           +ASRSNLK
Sbjct: 268 AASRSNLK 275
>NP_001094064
          Length = 765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           RSAS SN+K
Sbjct: 348 RSASPSNIK 356
>NP_060189
          Length = 765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           RSAS SN+K
Sbjct: 348 RSASPSNIK 356
>XP_005265303
          Length = 765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           RSAS SN+K
Sbjct: 348 RSASPSNIK 356
>XP_005265302
          Length = 765

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RSASRSNLK 9
           RSAS SN+K
Sbjct: 348 RSASPSNIK 356
>NP_001138747
          Length = 724

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 503 RSADSSNLK 511
>NP_001138748
          Length = 610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 389 RSADSSNLK 397
>NP_003401
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 584 RSADSSNLK 592
>NP_003402
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 580 RSADSSNLK 588
>NP_001171555
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 584 RSADSSNLK 592
>NP_001171556
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 584 RSADSSNLK 592
>XP_005262628
          Length = 750

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 529 RSADSSNLK 537
>XP_006724936
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 580 RSADSSNLK 588
>XP_005262627
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 580 RSADSSNLK 588
>XP_005274651
          Length = 780

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 559 RSADSSNLK 567
>XP_006724578
          Length = 797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 576 RSADSSNLK 584
>XP_005274649
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 584 RSADSSNLK 592
>XP_005274648
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 584 RSADSSNLK 592
>XP_006724577
          Length = 805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 584 RSADSSNLK 592
>XP_006724576
          Length = 844

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 623 RSADSSNLK 631
>NP_001171557
          Length = 576

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSA  SNLK
Sbjct: 355 RSADSSNLK 363
>NP_277052
          Length = 1731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSASRSNLK 9
           RSAS  NLK
Sbjct: 372 RSASDINLK 380
>NP_000287
          Length = 4302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 916 SASRANL 922
>NP_001009944
          Length = 4303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 916 SASRANL 922
>NP_001123910
          Length = 2477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1028 QSASRENL 1035
>NP_003118
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1028 QSASRENL 1035
>NP_001182461
          Length = 2452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1028 QSASRENL 1035
>NP_009029
          Length = 1640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1142 QSASRSN 1148
>NP_001826
          Length = 1583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1142 QSASRSN 1148
>NP_059344
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 259 SASKSNL 265
>NP_006331
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 259 SASKSNL 265
>NP_059345
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 259 SASKSNL 265
>XP_006726693
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 313 SASRANL 319
>XP_006724391
          Length = 1567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1163 QSASRSN 1169
>XP_005261338
          Length = 1570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1163 QSASRSN 1169
>XP_005277858
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1163 QSASRSN 1169
>XP_006724390
          Length = 1623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1125 QSASRSN 1131
>XP_006724389
          Length = 1653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1163 QSASRSN 1169
>XP_005277857
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RSASRSN 7
            +SASRSN
Sbjct: 1163 QSASRSN 1169
>XP_005257005
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 259 SASKSNL 265
>XP_006721701
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 253 SASKSNL 259
>XP_006721700
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 259 SASKSNL 265
>XP_005257002
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 292 SASKSNL 298
>XP_005257001
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 292 SASKSNL 298
>XP_006721699
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 292 SASKSNL 298
>XP_006721698
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 292 SASKSNL 298
>XP_005257000
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 292 SASKSNL 298
>XP_006720958
          Length = 2675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 953 SASRANL 959
>XP_006720957
          Length = 2688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 953 SASRANL 959
>XP_006720956
          Length = 3895

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 508 SASRANL 514
>XP_006720955
          Length = 4279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 892 SASRANL 898
>XP_006720954
          Length = 4334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 953 SASRANL 959
>XP_006720953
          Length = 4339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 953 SASRANL 959
>XP_006720952
          Length = 4340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SASR+NL
Sbjct: 953 SASRANL 959
>XP_006717317
          Length = 2498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1028 QSASRENL 1035
>XP_006717316
          Length = 2464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717315
          Length = 2469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717314
          Length = 2478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1028 QSASRENL 1035
>XP_006717313
          Length = 2483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717312
          Length = 2484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717311
          Length = 2489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717310
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717309
          Length = 2505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>XP_006717308
          Length = 2510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RSASRSNL 8
            +SASR NL
Sbjct: 1040 QSASRENL 1047
>NP_001138360
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SASRSNL 8
           SAS+SNL
Sbjct: 259 SASKSNL 265
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.105    0.237 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 248,323
Number of extensions: 285
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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