Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              20     390
NP_997229                                                              16    5631
NP_001277155                                                           16    5631
NP_001277156                                                           16    5631
NP_055998                                                              16    5631
NP_055927                                                              16    5631
NP_001158136                                                           16    5631
NP_004517                                                              16    5631
XP_006722754                                                           16    5631
XP_005259877                                                           16    5631
XP_006721884                                                           16    5631
XP_005257286                                                           16    5631
XP_006714675                                                           16    5631
XP_006714673                                                           16    5631
XP_006714672                                                           16    5631
XP_006714670                                                           16    5631
XP_006714669                                                           16    5631
XP_006714668                                                           16    5631
XP_006714667                                                           16    5631
XP_006714666                                                           16    5631
XP_005248555                                                           16    5631
XP_006714665                                                           16    5631
XP_005270716                                                           16    5631
XP_006710540                                                           16    5631
XP_006710539                                                           16    5631
XP_005270713                                                           16    5631
XP_005270712                                                           16    5631
XP_005270711                                                           16    5631
XP_005270710                                                           16    5631
XP_006710538                                                           16    5631
XP_005270709                                                           16    5631
NP_055790                                                              16    5631
NP_037408                                                              16    7355
NP_001241646                                                           15    9605
NP_001135441                                                           15    9605
NP_001135442                                                           15    9605
NP_001341                                                              15    9605
NP_077816                                                              15    9605
NP_085144                                                              15    9605
XP_006720682                                                           15    9605
XP_005268318                                                           15    9605
NP_055302                                                              15    9605
>NP_004251
          Length = 1208

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RRQVQRAFM 9
           RR+VQRAFM
Sbjct: 753 RRRVQRAFM 761
>NP_997229
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RRQVQRA 7
           RRQVQR+
Sbjct: 387 RRQVQRS 393
>NP_001277155
          Length = 2417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 403 RNQIQQAFV 411
>NP_001277156
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 415 RNQIQQAFV 423
>NP_055998
          Length = 2434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 420 RNQIQQAFV 428
>NP_055927
          Length = 1798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 551 RNQIQQAFV 559
>NP_001158136
          Length = 2623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 609 RNQIQQAFV 617
>NP_004517
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RRQVQRA 7
           RRQV+RA
Sbjct: 151 RRQVERA 157
>XP_006722754
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RRQVQRAFM 9
          R Q+Q+AF+
Sbjct: 12 RNQIQQAFV 20
>XP_005259877
          Length = 1394

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 237 RNQIQQAFV 245
>XP_006721884
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RRQVQRA 7
           RRQVQR+
Sbjct: 286 RRQVQRS 292
>XP_005257286
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RRQVQRA 7
           RRQVQR+
Sbjct: 387 RRQVQRS 393
>XP_006714675
          Length = 2275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 261 RNQIQQAFV 269
>XP_006714673
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 415 RNQIQQAFV 423
>XP_006714672
          Length = 2414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 400 RNQIQQAFV 408
>XP_006714670
          Length = 2425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 411 RNQIQQAFV 419
>XP_006714669
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 415 RNQIQQAFV 423
>XP_006714668
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 415 RNQIQQAFV 423
>XP_006714667
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 418 RNQIQQAFV 426
>XP_006714666
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 418 RNQIQQAFV 426
>XP_005248555
          Length = 2626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 612 RNQIQQAFV 620
>XP_006714665
          Length = 2651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 637 RNQIQQAFV 645
>XP_005270716
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 558 RNQIQQAFV 566
>XP_006710540
          Length = 1655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 408 RNQIQQAFV 416
>XP_006710539
          Length = 1683

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 436 RNQIQQAFV 444
>XP_005270713
          Length = 1711

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 464 RNQIQQAFV 472
>XP_005270712
          Length = 1720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 473 RNQIQQAFV 481
>XP_005270711
          Length = 1797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 551 RNQIQQAFV 559
>XP_005270710
          Length = 1804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 558 RNQIQQAFV 566
>XP_006710538
          Length = 1804

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 557 RNQIQQAFV 565
>XP_005270709
          Length = 1805

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 558 RNQIQQAFV 566
>NP_055790
          Length = 1570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRQVQRAFM 9
           R Q+Q+AF+
Sbjct: 413 RNQIQQAFV 421
>NP_037408
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RRQVQRAF 8
           +++VQRAF
Sbjct: 441 KQEVQRAF 448
>NP_001241646
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRQVQR 6
           RRQ+QR
Sbjct: 110 RRQIQR 115
>NP_001135441
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRQVQR 6
           RRQ+QR
Sbjct: 185 RRQIQR 190
>NP_001135442
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRQVQR 6
           RRQ+QR
Sbjct: 197 RRQIQR 202
>NP_001341
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRQVQR 6
           RRQ+QR
Sbjct: 185 RRQIQR 190
>NP_077816
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   RRQVQRAF 8
           RRQV R F
Sbjct: 208 RRQVVRGF 215
>NP_085144
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RRQVQRAF 8
           R QVQ+AF
Sbjct: 215 RVQVQKAF 222
>XP_006720682
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   RRQVQRAF 8
           RRQV R F
Sbjct: 208 RRQVVRGF 215
>XP_005268318
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   RRQVQRAF 8
           RRQV R F
Sbjct: 208 RRQVVRGF 215
>NP_055302
          Length = 320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  RRQVQRAF 8
          RRQ  RAF
Sbjct: 47 RRQKNRAF 54
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.355    0.142    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 379,423
Number of extensions: 705
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.2 bits)
S2: 28 (15.4 bits)

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