Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              19     869
NP_001263689                                                           19     869
NP_001119584                                                           19     869
NP_001119586                                                           19     869
NP_001263625                                                           19     869
NP_001119590                                                           19     869
NP_001263690                                                           19     869
NP_001119585                                                           19     869
NP_001263624                                                           19     869
NP_001119588                                                           19     869
NP_001119587                                                           19     869
NP_001119589                                                           19     869
NP_001263627                                                           19     869
NP_001263628                                                           19     869
NP_001263626                                                           19     869
NP_001171661                                                           17    2528
NP_004245                                                              17    2528
NP_001171665                                                           17    2528
NP_001171662                                                           17    2528
NP_999875                                                              17    3301
NP_001025035                                                           16    7355
NP_066001                                                              16    7355
XP_006711598                                                           16    7355
XP_006711597                                                           16    7355
XP_006711595                                                           16    7355
XP_006711594                                                           16    7355
NP_110391                                                              16    7355
NP_640337                                                              15    9605
NP_001121187                                                           15    9605
NP_056516                                                              15    9605
NP_055795                                                              15    9605
NP_001120869                                                           15    9605
NP_055463                                                              15    9605
NP_055431                                                              15    9605
NP_001275638                                                           15    9605
NP_065118                                                              15    9605
NP_001161707                                                           15    9605
NP_001266280                                                           15    9605
NP_001266278                                                           15    9605
NP_001266279                                                           15    9605
XP_006715402                                                           15    9605
XP_005247976                                                           15    9605
XP_005247975                                                           15    9605
XP_005247974                                                           15    9605
XP_005247973                                                           15    9605
XP_005247972                                                           15    9605
XP_005247971                                                           15    9605
XP_005247964                                                           15    9605
XP_006713889                                                           15    9605
XP_006713888                                                           15    9605
XP_005247300                                                           15    9605
NP_683762                                                              15    9605
>NP_000537
          Length = 393

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 248 RRPILTIIT 256
>NP_001263689
          Length = 354

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 209 RRPILTIIT 217
>NP_001119584
          Length = 393

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 248 RRPILTIIT 256
>NP_001119586
          Length = 341

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 248 RRPILTIIT 256
>NP_001263625
          Length = 302

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 209 RRPILTIIT 217
>NP_001119590
          Length = 354

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 209 RRPILTIIT 217
>NP_001263690
          Length = 354

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 209 RRPILTIIT 217
>NP_001119585
          Length = 346

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 248 RRPILTIIT 256
>NP_001263624
          Length = 307

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 209 RRPILTIIT 217
>NP_001119588
          Length = 209

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 116 RRPILTIIT 124
>NP_001119587
          Length = 261

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 116 RRPILTIIT 124
>NP_001119589
          Length = 214

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           RRPILTI T
Sbjct: 116 RRPILTIIT 124
>NP_001263627
          Length = 182

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RRPILTIST 9
          RRPILTI T
Sbjct: 89 RRPILTIIT 97
>NP_001263628
          Length = 187

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RRPILTIST 9
          RRPILTI T
Sbjct: 89 RRPILTIIT 97
>NP_001263626
          Length = 234

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RRPILTIST 9
          RRPILTI T
Sbjct: 89 RRPILTIIT 97
>NP_001171661
          Length = 542

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RRPILTIS 8
           RRPILT S
Sbjct: 149 RRPILTCS 156
>NP_004245
          Length = 542

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RRPILTIS 8
           RRPILT S
Sbjct: 149 RRPILTCS 156
>NP_001171665
          Length = 419

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RRPILTIS 8
          RRPILT S
Sbjct: 26 RRPILTCS 33
>NP_001171662
          Length = 451

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RRPILTIS 8
          RRPILT S
Sbjct: 58 RRPILTCS 65
>NP_999875
          Length = 283

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RPILTIST 9
          RP+LT++T
Sbjct: 10 RPLLTVAT 17
>NP_001025035
          Length = 1200

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RPILTIST 9
           RP+L +ST
Sbjct: 590 RPLLLVST 597
>NP_066001
          Length = 1190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RRPILTIST 9
           R P+L +ST
Sbjct: 870 RHPLLALST 878
>XP_006711598
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           +RP+LT S+
Sbjct: 107 QRPVLTASS 115
>XP_006711597
          Length = 319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           +RP+LT S+
Sbjct: 107 QRPVLTASS 115
>XP_006711595
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           +RP+LT S+
Sbjct: 107 QRPVLTASS 115
>XP_006711594
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           +RP+LT S+
Sbjct: 107 QRPVLTASS 115
>NP_110391
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRPILTIST 9
           +RP+LT S+
Sbjct: 107 QRPVLTASS 115
>NP_640337
          Length = 1115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LT+
Sbjct: 323 RRPCLTV 329
>NP_001121187
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LT+
Sbjct: 323 RRPCLTV 329
>NP_056516
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RPILTIST 9
           +P+LT+ T
Sbjct: 316 QPVLTVGT 323
>NP_055795
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LTI
Sbjct: 336 RRPSLTI 342
>NP_001120869
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RPILTIST 9
           +P+LT+ T
Sbjct: 316 QPVLTVGT 323
>NP_055463
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>NP_055431
          Length = 1177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    RPILTIST 9
            R ILT+ST
Sbjct: 1164 RSILTLST 1171
>NP_001275638
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  RRPILT 6
          RRP+LT
Sbjct: 48 RRPLLT 53
>NP_065118
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRPILT 6
           RRP+LT
Sbjct: 408 RRPLLT 413
>NP_001161707
          Length = 2139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RRPILTI 7
            ++PILTI
Sbjct: 1536 KKPILTI 1542
>NP_001266280
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRPILT 6
           RRP+LT
Sbjct: 315 RRPLLT 320
>NP_001266278
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRPILT 6
           RRP+LT
Sbjct: 236 RRPLLT 241
>NP_001266279
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RRPILT 6
           RRP+LT
Sbjct: 271 RRPLLT 276
>XP_006715402
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LT+
Sbjct: 323 RRPCLTV 329
>XP_005247976
          Length = 1002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 771 RPILTV 776
>XP_005247975
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247974
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247973
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247972
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247971
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RPILTI 7
           RPILT+
Sbjct: 977 RPILTV 982
>XP_005247964
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LTI
Sbjct: 336 RRPSLTI 342
>XP_006713889
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LTI
Sbjct: 336 RRPSLTI 342
>XP_006713888
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RRPILTI 7
           RRP LTI
Sbjct: 336 RRPSLTI 342
>XP_005247300
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RPILTIST 9
           R ILT+ST
Sbjct: 982 RSILTLST 989
>NP_683762
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RRPILTIS 8
           RRP LT++
Sbjct: 108 RRPSLTVA 115
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.140    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 582,181
Number of extensions: 1115
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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