Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     390
NP_001243297                                                           18    1935
NP_036467                                                              17    3301
XP_005272534                                                           17    3301
XP_005272533                                                           17    3301
XP_005272532                                                           17    3301
NP_689635                                                              17    4312
NP_001240759                                                           17    4312
NP_818931                                                              17    4312
NP_001240758                                                           17    4312
NP_001128662                                                           17    4312
NP_056057                                                              17    4312
NP_001035207                                                           17    4312
XP_006719241                                                           17    4312
XP_006717021                                                           17    4312
XP_005251769                                                           17    4312
XP_006717020                                                           17    4312
XP_005251768                                                           17    4312
NP_065988                                                              16    5631
NP_689672                                                              16    5631
NP_059984                                                              16    5631
XP_006724893                                                           16    5631
XP_005274763                                                           16    5631
XP_006724892                                                           16    5631
XP_005274762                                                           16    5631
XP_005267986                                                           16    5631
XP_006716240                                                           16    5631
NP_001268231                                                           16    7355
NP_115756                                                              16    7355
NP_733792                                                              16    7355
NP_733781                                                              16    7355
NP_203126                                                              16    7355
NP_001245320                                                           16    7355
XP_005276467                                                           16    7355
XP_006720086                                                           16    7355
XP_006720085                                                           16    7355
XP_006720084                                                           16    7355
XP_006718833                                                           16    7355
XP_006714784                                                           16    7355
NP_000159                                                              15    9605
NP_002825                                                              15    9605
NP_001003703                                                           15    9605
NP_001003697                                                           15    9605
NP_001676                                                              15    9605
NP_001003696                                                           15    9605
NP_001003701                                                           15    9605
NP_001186804                                                           15    9605
NP_542376                                                              15    9605
NP_004361                                                              15    9605
NP_001265253                                                           15    9605
XP_005261049                                                           15    9605
XP_006719590                                                           15    9605
XP_006719589                                                           15    9605
XP_005268685                                                           15    9605
XP_006719245                                                           15    9605
XP_006719244                                                           15    9605
XP_005249761                                                           15    9605
XP_005249760                                                           15    9605
XP_006715397                                                           15    9605
NP_001094090                                                           15    9605
NP_005471                                                              15    9605
>NP_115803
          Length = 1156

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRNVGIMQP 9
           RRNVG MQP
Sbjct: 805 RRNVGNMQP 813
>NP_001243297
          Length = 102

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RNVGIMQP 9
          RN+G++QP
Sbjct: 30 RNLGLLQP 37
>NP_036467
          Length = 1098

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRNVGIMQP 9
           R+N+G+M P
Sbjct: 222 RQNLGLMTP 230
>XP_005272534
          Length = 1071

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRNVGIMQP 9
           R+N+G+M P
Sbjct: 222 RQNLGLMTP 230
>XP_005272533
          Length = 1096

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRNVGIMQP 9
           R+N+G+M P
Sbjct: 222 RQNLGLMTP 230
>XP_005272532
          Length = 1100

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRNVGIMQP 9
           R+N+G+M P
Sbjct: 222 RQNLGLMTP 230
>NP_689635
          Length = 806

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 427 RRNVECLQP 435
>NP_001240759
          Length = 749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 375 RRNVECLQP 383
>NP_818931
          Length = 754

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 375 RRNVECLQP 383
>NP_001240758
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 429 RRNVECLQP 437
>NP_001128662
          Length = 1133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RRNVGIMQ 8
           RRNVGI +
Sbjct: 903 RRNVGIRE 910
>NP_056057
          Length = 1205

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RRNVGIMQ 8
           RRNVGI +
Sbjct: 964 RRNVGIRE 971
>NP_001035207
          Length = 1450

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RRNVGIMQ 8
            RRNVGI +
Sbjct: 1209 RRNVGIRE 1216
>XP_006719241
          Length = 344

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          +RN GI+ P
Sbjct: 50 KRNAGILAP 58
>XP_006717021
          Length = 630

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 251 RRNVECLQP 259
>XP_005251769
          Length = 703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 324 RRNVECLQP 332
>XP_006717020
          Length = 754

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 375 RRNVECLQP 383
>XP_005251768
          Length = 754

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRNV  +QP
Sbjct: 375 RRNVECLQP 383
>NP_065988
          Length = 2048

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RRNVGIMQP 9
            R+NVGI  P
Sbjct: 1954 RKNVGIHVP 1962
>NP_689672
          Length = 402

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RNVGIMQP 9
           RN+G +QP
Sbjct: 331 RNLGSLQP 338
>NP_059984
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VGIMQP 9
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_006724893
          Length = 1719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VGIMQP 9
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_005274763
          Length = 1789

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VGIMQP 9
           VG+MQP
Sbjct: 614 VGVMQP 619
>XP_006724892
          Length = 1841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VGIMQP 9
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_005274762
          Length = 1853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VGIMQP 9
           VG+MQP
Sbjct: 696 VGVMQP 701
>XP_005267986
          Length = 2022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RRNVGIMQP 9
            R+NVGI  P
Sbjct: 1928 RKNVGIHVP 1936
>XP_006716240
          Length = 213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  RNVGIMQP 9
          RN+G +QP
Sbjct: 15 RNLGSLQP 22
>NP_001268231
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RNVGIM 7
           RN+GIM
Sbjct: 103 RNIGIM 108
>NP_115756
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  RNVGIM 7
          RN+GIM
Sbjct: 71 RNIGIM 76
>NP_733792
          Length = 732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  RNVGIM 7
          RN+GIM
Sbjct: 71 RNIGIM 76
>NP_733781
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  RNVGIM 7
          RN+GIM
Sbjct: 71 RNIGIM 76
>NP_203126
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RRNVGIMQP 9
           RR++G +QP
Sbjct: 161 RRDLGRLQP 169
>NP_001245320
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RRNVGIMQP 9
          RRN  I QP
Sbjct: 12 RRNKAIAQP 20
>XP_005276467
          Length = 97

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  NVGIMQP 9
          N+G++QP
Sbjct: 91 NLGLLQP 97
>XP_006720086
          Length = 703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NVGIMQP 9
           N+G++QP
Sbjct: 691 NLGLLQP 697
>XP_006720085
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NVGIMQP 9
           N+G++QP
Sbjct: 692 NLGLLQP 698
>XP_006720084
          Length = 730

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   NVGIMQP 9
           N+G++QP
Sbjct: 718 NLGLLQP 724
>XP_006718833
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RRNVGIMQP 9
          RRN  I QP
Sbjct: 12 RRNKAIAQP 20
>XP_006714784
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  RNVGIM 7
          RN+GIM
Sbjct: 71 RNIGIM 76
>NP_000159
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RRNVGIMQP 9
          RRN   MQP
Sbjct: 54 RRNAITMQP 62
>NP_002825
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NVGIMQ 8
           NVG+MQ
Sbjct: 582 NVGLMQ 587
>NP_001003703
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  RRNVGI 6
          RRN+G+
Sbjct: 22 RRNIGV 27
>NP_001003697
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  RRNVGI 6
          RRN+G+
Sbjct: 22 RRNIGV 27
>NP_001676
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  RRNVGI 6
          RRN+G+
Sbjct: 22 RRNIGV 27
>NP_001003696
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  RRNVGI 6
          RRN+G+
Sbjct: 22 RRNIGV 27
>NP_001003701
          Length = 116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  RRNVGI 6
          RRN+G+
Sbjct: 30 RRNIGV 35
>NP_001186804
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          ++ VG+ QP
Sbjct: 37 KQRVGVQQP 45
>NP_542376
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RRNVGIMQP 9
           RRN  I+QP
Sbjct: 912 RRNNVILQP 920
>NP_004361
          Length = 3063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RRNVGIMQP 9
            RRN  I+QP
Sbjct: 2076 RRNNVILQP 2084
>NP_001265253
          Length = 126

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          +R VGI QP
Sbjct: 80 QRLVGISQP 88
>XP_005261049
          Length = 108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1  RRNVGI 6
          RRN+G+
Sbjct: 22 RRNIGV 27
>XP_006719590
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NVGIMQ 8
           NVG+MQ
Sbjct: 548 NVGLMQ 553
>XP_006719589
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   NVGIMQ 8
           NVG+MQ
Sbjct: 586 NVGLMQ 591
>XP_005268685
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   RRNVGIMQP 9
           R N+G M P
Sbjct: 451 RENIGNMPP 459
>XP_006719245
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          +R VGI QP
Sbjct: 80 QRLVGISQP 88
>XP_006719244
          Length = 868

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          +R VGI QP
Sbjct: 80 QRLVGISQP 88
>XP_005249761
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RRNVGIMQP 9
          RRN   MQP
Sbjct: 54 RRNAITMQP 62
>XP_005249760
          Length = 1580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RRNVGIMQP 9
          RRN   MQP
Sbjct: 54 RRNAITMQP 62
>XP_006715397
          Length = 2972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RRNVGIMQP 9
            RRN  I+QP
Sbjct: 1985 RRNNVILQP 1993
>NP_001094090
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          +R VGI QP
Sbjct: 80 QRLVGISQP 88
>NP_005471
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RRNVGIMQP 9
          +R VGI QP
Sbjct: 80 QRLVGISQP 88
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.144    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 489,011
Number of extensions: 928
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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