Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005624                                                              17    3301
XP_005264572                                                           17    3301
NP_659410                                                              17    4312
NP_114141                                                              17    4312
XP_005253387                                                           17    4312
XP_006719103                                                           17    4312
XP_005253384                                                           17    4312
XP_005253383                                                           17    4312
NP_006280                                                              16    5631
NP_055874                                                              16    5631
XP_006720784                                                           16    5631
XP_006720783                                                           16    5631
XP_006720782                                                           16    5631
XP_006720781                                                           16    5631
XP_005254772                                                           16    5631
XP_005254771                                                           16    5631
XP_006720780                                                           16    5631
XP_005254769                                                           16    5631
XP_005254770                                                           16    5631
XP_005254765                                                           16    5631
XP_005254767                                                           16    5631
XP_006720779                                                           16    5631
XP_005254768                                                           16    5631
XP_005254764                                                           16    5631
XP_006716915                                                           16    5631
XP_005251621                                                           16    5631
NP_001012425                                                           16    7355
NP_001153889                                                           16    7355
NP_110403                                                              16    7355
NP_001153890                                                           16    7355
NP_001153891                                                           16    7355
NP_001276062                                                           16    7355
NP_001189788                                                           16    7355
NP_001123513                                                           16    7355
NP_003020                                                              16    7355
NP_001123512                                                           16    7355
NP_892113                                                              16    7355
NP_001002860                                                           16    7355
NP_060612                                                              16    7355
XP_006725229                                                           16    7355
XP_006723941                                                           16    7355
XP_006720258                                                           16    7355
XP_006719928                                                           16    7355
XP_005273615                                                           16    7355
XP_006716418                                                           16    7355
XP_005273614                                                           16    7355
XP_005273613                                                           16    7355
XP_005273612                                                           16    7355
XP_005245509                                                           16    7355
XP_005245508                                                           16    7355
XP_005245507                                                           16    7355
XP_005245506                                                           16    7355
NP_078822                                                              16    7355
NP_006341                                                              15    9605
NP_037541                                                              15    9605
NP_001269676                                                           15    9605
NP_001269675                                                           15    9605
NP_001269674                                                           15    9605
NP_001104740                                                           15    9605
NP_775104                                                              15    9605
NP_009145                                                              15    9605
NP_891992                                                              15    9605
NP_036265                                                              15    9605
NP_001276962                                                           15    9605
XP_005252438                                                           15    9605
XP_005252437                                                           15    9605
XP_005248460                                                           15    9605
XP_005248459                                                           15    9605
XP_005248458                                                           15    9605
XP_005248457                                                           15    9605
NP_057212                                                              15    9605
>NP_005624
          Length = 1333

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QAVNMMCQ 9
          Q +NM+CQ
Sbjct: 54 QLLNMLCQ 61
>XP_005264572
          Length = 1318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QAVNMMCQ 9
          Q +NM+CQ
Sbjct: 54 QLLNMLCQ 61
>NP_659410
          Length = 1274

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RQAVNMMC 8
          + AVNM+C
Sbjct: 74 QDAVNMLC 81
>NP_114141
          Length = 5635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QAVNMMCQ 9
            QAV ++CQ
Sbjct: 2119 QAVELLCQ 2126
>XP_005253387
          Length = 1156

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQAVNMMC 8
           + AVNM+C
Sbjct: 96  QDAVNMLC 103
>XP_006719103
          Length = 1296

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQAVNMMC 8
           + AVNM+C
Sbjct: 96  QDAVNMLC 103
>XP_005253384
          Length = 1311

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RQAVNMMC 8
          + AVNM+C
Sbjct: 74 QDAVNMLC 81
>XP_005253383
          Length = 1333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQAVNMMC 8
           + AVNM+C
Sbjct: 96  QDAVNMLC 103
>NP_006280
          Length = 2541

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1472 QAIQMACQ 1479
>NP_055874
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_006720784
          Length = 2502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_006720783
          Length = 2512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1429 QAIQMACQ 1436
>XP_006720782
          Length = 2517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_006720781
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254772
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254771
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_006720780
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254769
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254770
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254765
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254767
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_006720779
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254768
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_005254764
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1474 QAIQMACQ 1481
>XP_006716915
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1472 QAIQMACQ 1479
>XP_005251621
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    QAVNMMCQ 9
            QA+ M CQ
Sbjct: 1472 QAIQMACQ 1479
>NP_001012425
          Length = 180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3   AVNMMC 8
           A+N+MC
Sbjct: 127 AINLMC 132
>NP_001153889
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   VNMMCQ 9
           +NM+CQ
Sbjct: 185 INMICQ 190
>NP_110403
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   VNMMCQ 9
           +NM+CQ
Sbjct: 186 INMICQ 191
>NP_001153890
          Length = 354

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   VNMMCQ 9
           +NM+CQ
Sbjct: 111 INMICQ 116
>NP_001153891
          Length = 248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   VNMMCQ 9
           +NM+CQ
Sbjct: 186 INMICQ 191
>NP_001276062
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  RQAVNMMCQ 9
          RQA++ +C+
Sbjct: 69 RQALHFLCE 77
>NP_001189788
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1  RQAVNMMCQ 9
          R+A++++C+
Sbjct: 34 REAISLVCE 42
>NP_001123513
          Length = 473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1  RQAVNMMCQ 9
          R+A++++C+
Sbjct: 79 REAISLVCE 87
>NP_003020
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1  RQAVNMMCQ 9
          R+A++++C+
Sbjct: 79 REAISLVCE 87
>NP_001123512
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1   RQAVNMMCQ 9
           R+A++++C+
Sbjct: 189 REAISLVCE 197
>NP_892113
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1   RQAVNMMCQ 9
           R+A++++C+
Sbjct: 189 REAISLVCE 197
>NP_001002860
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RQAVNMMCQ 9
           RQA++ +C+
Sbjct: 420 RQALHFLCE 428
>NP_060612
          Length = 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           +AVN +CQ
Sbjct: 606 KAVNKICQ 613
>XP_006725229
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RQAVNMMCQ 9
           RQA++ +C+
Sbjct: 420 RQALHFLCE 428
>XP_006723941
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   VNMMCQ 9
           +NM+CQ
Sbjct: 135 INMICQ 140
>XP_006720258
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RQAVNMMCQ 9
           RQA++ +C+
Sbjct: 420 RQALHFLCE 428
>XP_006719928
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RQAVNMMCQ 9
           ++A+N +CQ
Sbjct: 187 KEAMNSICQ 195
>XP_005273615
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           +AVN +CQ
Sbjct: 378 KAVNKICQ 385
>XP_006716418
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           +AVN +CQ
Sbjct: 494 KAVNKICQ 501
>XP_005273614
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           +AVN +CQ
Sbjct: 607 KAVNKICQ 614
>XP_005273613
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           +AVN +CQ
Sbjct: 606 KAVNKICQ 613
>XP_005273612
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           +AVN +CQ
Sbjct: 607 KAVNKICQ 614
>XP_005245509
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1  RQAVNMMCQ 9
          R+A++++C+
Sbjct: 79 REAISLVCE 87
>XP_005245508
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1  RQAVNMMCQ 9
          R+A++++C+
Sbjct: 79 REAISLVCE 87
>XP_005245507
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1   RQAVNMMCQ 9
           R+A++++C+
Sbjct: 189 REAISLVCE 197
>XP_005245506
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1   RQAVNMMCQ 9
           R+A++++C+
Sbjct: 189 REAISLVCE 197
>NP_078822
          Length = 726

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RQAVNMMCQ 9
           ++A+N +CQ
Sbjct: 264 KEAMNSICQ 272
>NP_006341
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RQAVNMMCQ 9
          RQA N  CQ
Sbjct: 35 RQAKNGRCQ 43
>NP_037541
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RQAVNMMCQ 9
          RQA N  CQ
Sbjct: 35 RQAKNGRCQ 43
>NP_001269676
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  QAVNMMCQ 9
          QA++ MC+
Sbjct: 75 QAISAMCE 82
>NP_001269675
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ MC+
Sbjct: 338 QAISAMCE 345
>NP_001269674
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ MC+
Sbjct: 338 QAISAMCE 345
>NP_001104740
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QAVNMMC 8
           QAV +MC
Sbjct: 360 QAVEVMC 366
>NP_775104
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ MC+
Sbjct: 338 QAISAMCE 345
>NP_009145
          Length = 760

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RQAVNMMCQ 9
           ++ VN++CQ
Sbjct: 334 QEMVNVICQ 342
>NP_891992
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QAVNMMC 8
           QAV +MC
Sbjct: 321 QAVEVMC 327
>NP_036265
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ +CQ
Sbjct: 381 QAISALCQ 388
>NP_001276962
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ +CQ
Sbjct: 381 QAISALCQ 388
>XP_005252438
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ MC+
Sbjct: 250 QAISAMCE 257
>XP_005252437
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ MC+
Sbjct: 273 QAISAMCE 280
>XP_005248460
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RQAVNMMCQ 9
          RQA N  CQ
Sbjct: 35 RQAKNGRCQ 43
>XP_005248459
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RQAVNMMCQ 9
          RQA N  CQ
Sbjct: 35 RQAKNGRCQ 43
>XP_005248458
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RQAVNMMCQ 9
          RQA N  CQ
Sbjct: 35 RQAKNGRCQ 43
>XP_005248457
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RQAVNMMCQ 9
          RQA N  CQ
Sbjct: 35 RQAKNGRCQ 43
>NP_057212
          Length = 874

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   QAVNMMCQ 9
           QA++ +CQ
Sbjct: 381 QAISALCQ 388
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.123    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 378,102
Number of extensions: 425
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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