Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001155973                                                           20     390
NP_055903                                                              20     390
NP_001073896                                                           17    4312
NP_001162593                                                           17    4312
NP_002016                                                              17    4312
NP_001162594                                                           17    4312
NP_001162595                                                           17    4312
NP_001162596                                                           17    4312
NP_001164099                                                           17    4312
XP_005263859                                                           17    4312
NP_001157032                                                           16    5631
NP_689977                                                              16    5631
NP_001007227                                                           16    5631
NP_003554                                                              16    5631
NP_001007230                                                           16    5631
NP_001007228                                                           16    5631
NP_001007231                                                           16    5631
NP_001007229                                                           16    5631
NP_997002                                                              16    5631
NP_001137307                                                           16    5631
NP_006156                                                              16    5631
NP_001265141                                                           16    5631
NP_001265140                                                           16    5631
NP_060675                                                              16    5631
XP_005257781                                                           16    5631
XP_005257780                                                           16    5631
XP_005271626                                                           16    5631
XP_005271625                                                           16    5631
XP_005271624                                                           16    5631
XP_005271623                                                           16    5631
XP_005271622                                                           16    5631
NP_001265381                                                           15    9605
NP_001265380                                                           15    9605
NP_001265382                                                           15    9605
NP_009124                                                              15    9605
NP_009168                                                              15    9605
NP_001005176                                                           15    9605
NP_001007254                                                           15    9605
NP_663782                                                              15    9605
NP_036260                                                              15    9605
NP_006724                                                              15    9605
NP_001118                                                              15    9605
NP_001163801                                                           15    9605
XP_005262168                                                           15    9605
XP_005257995                                                           15    9605
XP_005257994                                                           15    9605
XP_006714136                                                           15    9605
XP_005246315                                                           15    9605
XP_006712289                                                           15    9605
XP_005246314                                                           15    9605
XP_005246313                                                           15    9605
XP_005246312                                                           15    9605
XP_005246311                                                           15    9605
XP_005246310                                                           15    9605
XP_006712288                                                           15    9605
XP_006712287                                                           15    9605
XP_005246309                                                           15    9605
XP_006712286                                                           15    9605
XP_006710516                                                           15    9605
NP_001159491                                                           15    9605
NP_001273                                                              15    9605
NP_001025177                                                           15    9605
>NP_001155973
          Length = 1833

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RNVSGQNRI 9
           RNVSGQ+RI
Sbjct: 285 RNVSGQDRI 293
>NP_055903
          Length = 1723

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RNVSGQNRI 9
           RNVSGQ+RI
Sbjct: 285 RNVSGQDRI 293
>NP_001073896
          Length = 1577

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNVSGQNR 8
            +N+SG+NR
Sbjct: 1494 KNLSGKNR 1501
>NP_001162593
          Length = 1276

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNVSGQN 7
           RNVSG N
Sbjct: 895 RNVSGNN 901
>NP_002016
          Length = 1311

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNVSGQN 7
           RNVSG N
Sbjct: 928 RNVSGNN 934
>NP_001162594
          Length = 1301

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNVSGQN 7
           RNVSG N
Sbjct: 918 RNVSGNN 924
>NP_001162595
          Length = 1276

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNVSGQN 7
           RNVSG N
Sbjct: 893 RNVSGNN 899
>NP_001162596
          Length = 1272

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNVSGQN 7
           RNVSG N
Sbjct: 889 RNVSGNN 895
>NP_001164099
          Length = 952

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNVSGQN 7
           RNVSG N
Sbjct: 569 RNVSGNN 575
>XP_005263859
          Length = 1606

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNVSGQNR 8
            +N+SG+NR
Sbjct: 1523 KNLSGKNR 1530
>NP_001157032
          Length = 471

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RN+SGQ  +
Sbjct: 463 RNLSGQKHV 471
>NP_689977
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RN+SGQ  +
Sbjct: 434 RNLSGQKHV 442
>NP_001007227
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_003554
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007230
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007228
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007231
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_001007229
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>NP_997002
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RNVSGQ 6
          RNVSGQ
Sbjct: 46 RNVSGQ 51
>NP_001137307
          Length = 1299

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +NV+GQN I
Sbjct: 911 QNVTGQNII 919
>NP_006156
          Length = 1324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +NV+GQN I
Sbjct: 936 QNVTGQNII 944
>NP_001265141
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RNVSGQ 6
          RNVSGQ
Sbjct: 46 RNVSGQ 51
>NP_001265140
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RNVSGQ 6
          RNVSGQ
Sbjct: 46 RNVSGQ 51
>NP_060675
          Length = 128

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RNVSGQ 6
          RNVSGQ
Sbjct: 46 RNVSGQ 51
>XP_005257781
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>XP_005257780
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   NVSGQN 7
           N+SGQN
Sbjct: 169 NISGQN 174
>XP_005271626
          Length = 1294

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RNVSGQNRI 9
            +NV+GQN I
Sbjct: 995  QNVTGQNII 1003
>XP_005271625
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +NV+GQN I
Sbjct: 923 QNVTGQNII 931
>XP_005271624
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +NV+GQN I
Sbjct: 923 QNVTGQNII 931
>XP_005271623
          Length = 1371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +NV+GQN I
Sbjct: 983 QNVTGQNII 991
>XP_005271622
          Length = 1383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RNVSGQNRI 9
            +NV+GQN I
Sbjct: 995  QNVTGQNII 1003
>NP_001265381
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>NP_001265380
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>NP_001265382
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>NP_009124
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +N+SGQ+ +
Sbjct: 215 QNISGQDMV 223
>NP_009168
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>NP_001005176
          Length = 172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>NP_001007254
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV  QNR+
Sbjct: 544 RNVIYQNRL 552
>NP_663782
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 881 RNVEGQDML 889
>NP_036260
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VSGQNRI 9
           +SG+NR+
Sbjct: 191 ISGRNRV 197
>NP_006724
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  RNVSGQNR 8
          +NV  QNR
Sbjct: 8  KNVQAQNR 15
>NP_001118
          Length = 949

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 888 RNVEGQDML 896
>NP_001163801
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  RNVSGQNR 8
          +NV G NR
Sbjct: 15 QNVEGNNR 22
>XP_005262168
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  RNVSGQNR 8
          +NV  QNR
Sbjct: 8  KNVQAQNR 15
>XP_005257995
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 893 RNVEGQDML 901
>XP_005257994
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 893 RNVEGQDML 901
>XP_006714136
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNVSGQNRI 9
           +N+SGQ+ +
Sbjct: 238 QNISGQDMV 246
>XP_005246315
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_006712289
          Length = 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_005246314
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_005246313
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_005246312
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_005246311
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_005246310
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_006712288
          Length = 845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_006712287
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 6  QNVEGQN 12
>XP_005246309
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_006712286
          Length = 867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  RNVSGQN 7
          +NV GQN
Sbjct: 26 QNVEGQN 32
>XP_006710516
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   VSGQNRI 9
           +SG+NR+
Sbjct: 191 ISGRNRV 197
>NP_001159491
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 861 RNVEGQDML 869
>NP_001273
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 879 RNVEGQDML 887
>NP_001025177
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNVSGQNRI 9
           RNV GQ+ +
Sbjct: 893 RNVEGQDML 901
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.130    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 570,801
Number of extensions: 871
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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