Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     509
NP_001263689                                                           20     509
NP_001119584                                                           20     509
NP_001119586                                                           20     509
NP_001263625                                                           20     509
NP_001119590                                                           20     509
NP_001263690                                                           20     509
NP_001119585                                                           20     509
NP_001263624                                                           20     509
NP_001119588                                                           20     509
NP_001119587                                                           20     509
NP_001119589                                                           20     509
NP_001263627                                                           20     509
NP_001263628                                                           20     509
NP_001263626                                                           20     509
NP_060034                                                              17    4312
NP_653213                                                              17    4312
XP_006719539                                                           17    4312
NP_001274141                                                           16    5631
NP_001269714                                                           16    5631
NP_066928                                                              16    5631
NP_612152                                                              16    5631
NP_006368                                                              16    5631
NP_060476                                                              16    5631
NP_065867                                                              16    5631
NP_001116291                                                           16    5631
NP_001269711                                                           16    5631
XP_006716779                                                           16    5631
XP_006715715                                                           16    5631
XP_005247595                                                           16    5631
XP_005246008                                                           16    5631
XP_005246007                                                           16    5631
NP_001186907                                                           16    7355
XP_006722450                                                           16    7355
XP_006722449                                                           16    7355
XP_006722448                                                           16    7355
XP_006722447                                                           16    7355
XP_006713775                                                           16    7355
NP_001186908                                                           16    7355
NP_064551                                                              15    9605
NP_542415                                                              15    9605
NP_542416                                                              15    9605
NP_542414                                                              15    9605
NP_006255                                                              15    9605
NP_776158                                                              15    9605
NP_001107865                                                           15    9605
NP_001107866                                                           15    9605
NP_005083                                                              15    9605
XP_005248509                                                           15    9605
XP_006714626                                                           15    9605
XP_006714625                                                           15    9605
XP_005248508                                                           15    9605
XP_006714624                                                           15    9605
XP_005263224                                                           15    9605
XP_006713765                                                           15    9605
NP_056471                                                              15    9605
>NP_000537
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 267 RNSFEVRV 274
>NP_001263689
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 228 RNSFEVRV 235
>NP_001119584
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 267 RNSFEVRV 274
>NP_001119586
          Length = 341

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 267 RNSFEVRV 274
>NP_001263625
          Length = 302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 228 RNSFEVRV 235
>NP_001119590
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 228 RNSFEVRV 235
>NP_001263690
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 228 RNSFEVRV 235
>NP_001119585
          Length = 346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 267 RNSFEVRV 274
>NP_001263624
          Length = 307

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 228 RNSFEVRV 235
>NP_001119588
          Length = 209

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 135 RNSFEVRV 142
>NP_001119587
          Length = 261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 135 RNSFEVRV 142
>NP_001119589
          Length = 214

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 135 RNSFEVRV 142
>NP_001263627
          Length = 182

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 108 RNSFEVRV 115
>NP_001263628
          Length = 187

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 108 RNSFEVRV 115
>NP_001263626
          Length = 234

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNSFEVRV
Sbjct: 108 RNSFEVRV 115
>NP_060034
          Length = 2551

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RNSFEVRVY 9
          R +FEVR Y
Sbjct: 72 RYTFEVRTY 80
>NP_653213
          Length = 2211

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NSFEVRVY 9
           N +EV+VY
Sbjct: 172 NKYEVKVY 179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNSFEVRV 8
            RN++EV+V
Sbjct: 1021 RNTYEVQV 1028
>XP_006719539
          Length = 2246

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RNSFEVRVY 9
          R +FEVR Y
Sbjct: 72 RYTFEVRTY 80
>NP_001274141
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNS++VR+
Sbjct: 342 RNSYDVRL 349
>NP_001269714
          Length = 376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNSFEVR 7
           RN FEVR
Sbjct: 152 RNRFEVR 158
>NP_066928
          Length = 318

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           +NSF  RVY
Sbjct: 132 KNSFGQRVY 140
>NP_612152
          Length = 2849

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RNS E RV+
Sbjct: 874 RNSSETRVF 882
>NP_006368
          Length = 1591

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NSFEVRV 8
            NSF+VR+
Sbjct: 1224 NSFQVRI 1230
>NP_060476
          Length = 421

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RNSFEVR 7
           RN FEVR
Sbjct: 152 RNRFEVR 158
>NP_065867
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNS++VR+
Sbjct: 442 RNSYDVRL 449
>NP_001116291
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNS++VR+
Sbjct: 442 RNSYDVRL 449
>NP_001269711
          Length = 307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RNSFEVR 7
          RN FEVR
Sbjct: 38 RNRFEVR 44
>XP_006716779
          Length = 2399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    NSFEVRV 8
            NSF+VR+
Sbjct: 2032 NSFQVRI 2038
>XP_006715715
          Length = 2023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RNS E RV+
Sbjct: 826 RNSSETRVF 834
>XP_005247595
          Length = 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RNSFEVRVY 9
          +NSF  RVY
Sbjct: 51 KNSFGQRVY 59
>XP_005246008
          Length = 984

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNS++VR+
Sbjct: 442 RNSYDVRL 449
>XP_005246007
          Length = 985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RNS++VR+
Sbjct: 442 RNSYDVRL 449
>NP_001186907
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           +NSF  R+Y
Sbjct: 120 KNSFGQRIY 128
>XP_006722450
          Length = 1249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RNSFEVRV 8
          RN++EV+V
Sbjct: 52 RNTYEVQV 59
>XP_006722449
          Length = 1256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RNSFEVRV 8
          RN++EV+V
Sbjct: 52 RNTYEVQV 59
>XP_006722448
          Length = 1304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RNSFEVRV 8
          RN++EV+V
Sbjct: 52 RNTYEVQV 59
>XP_006722447
          Length = 1933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RNSFEVRV 8
           RN++EV+V
Sbjct: 743 RNTYEVQV 750
>XP_006713775
          Length = 224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RNSFEVRVY 9
          +NSF  R+Y
Sbjct: 47 KNSFGQRIY 55
>NP_001186908
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           +NSF  R+Y
Sbjct: 116 KNSFGQRIY 124
>NP_064551
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   NSFEVRVY 9
           ++FE R+Y
Sbjct: 380 HAFEARIY 387
>NP_542415
          Length = 2294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    NSFEVRVY 9
            N+FEV+++
Sbjct: 1307 NTFEVKLF 1314
>NP_542416
          Length = 2490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    NSFEVRVY 9
            N+FEV+++
Sbjct: 1503 NTFEVKLF 1510
>NP_542414
          Length = 2485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    NSFEVRVY 9
            N+FEV+++
Sbjct: 1498 NTFEVKLF 1505
>NP_006255
          Length = 2466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    NSFEVRVY 9
            N+FEV+++
Sbjct: 1479 NTFEVKLF 1486
>NP_776158
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RN+F +R Y
Sbjct: 289 RNTFLLRTY 297
>NP_001107865
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RN+F +R Y
Sbjct: 289 RNTFLLRTY 297
>NP_001107866
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RN+F +R Y
Sbjct: 289 RNTFLLRTY 297
>NP_005083
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FEVRVY 9
           FEVR+Y
Sbjct: 135 FEVRLY 140
>XP_005248509
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RNSFEVRVY 9
          RN+F +R Y
Sbjct: 60 RNTFLLRTY 68
>XP_006714626
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RNSFEVRVY 9
          RN+F +R Y
Sbjct: 66 RNTFLLRTY 74
>XP_006714625
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RN+F +R Y
Sbjct: 289 RNTFLLRTY 297
>XP_005248508
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RN+F +R Y
Sbjct: 285 RNTFLLRTY 293
>XP_006714624
          Length = 484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNSFEVRVY 9
           RN+F +R Y
Sbjct: 289 RNTFLLRTY 297
>XP_005263224
          Length = 2491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2    NSFEVRVY 9
            N+FEV+++
Sbjct: 1504 NTFEVKLF 1511
>XP_006713765
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   NSFEVRVY 9
           ++FE R+Y
Sbjct: 271 HAFEARIY 278
>NP_056471
          Length = 1882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    RNSFEVRVY 9
            +  FE++VY
Sbjct: 1743 KEPFEIKVY 1751
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.140    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 426,367
Number of extensions: 734
Number of successful extensions: 57
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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