Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_071754                                                              18    1482
NP_001185763                                                           18    1482
NP_001002810                                                           18    1482
NP_055459                                                              18    1482
NP_001182189                                                           18    1482
NP_001002812                                                           18    1482
NP_001182190                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
NP_004953                                                              17    4312
XP_006717825                                                           17    4312
NP_004841                                                              16    5631
NP_056386                                                              16    5631
NP_008893                                                              16    5631
NP_001171570                                                           16    5631
NP_001007089                                                           16    5631
XP_006715520                                                           16    5631
XP_005246247                                                           16    5631
NP_001093879                                                           16    5631
NP_005742                                                              16    7355
NP_671714                                                              16    7355
NP_001248770                                                           16    7355
XP_006723569                                                           16    7355
XP_005259486                                                           16    7355
XP_005255642                                                           16    7355
XP_006715890                                                           16    7355
XP_005250160                                                           16    7355
XP_005250159                                                           16    7355
NP_001098719                                                           16    7355
NP_001098718                                                           16    7355
NP_079056                                                              16    7355
NP_001074001                                                           16    7355
NP_001073926                                                           16    7355
NP_000811                                                              15    9605
NP_001137417                                                           15    9605
NP_001137418                                                           15    9605
NP_001120670                                                           15    9605
NP_009198                                                              15    9605
NP_001192                                                              15    9605
XP_005257055                                                           15    9605
XP_005257053                                                           15    9605
XP_005257052                                                           15    9605
XP_006714354                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 113 RNIELKVEV 121
>NP_071754
          Length = 310

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 184 RNIELKVEV 192
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 47 RNIELKVEV 55
>NP_001002810
          Length = 173

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 47 RNIELKVEV 55
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 47 RNIELKVEV 55
>NP_001182189
          Length = 141

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 15 RNIELKVEV 23
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 47 RNIELKVEV 55
>NP_001182190
          Length = 176

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 50 RNIELKVEV 58
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 113 RNIELKVEV 121
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 113 RNIELKVEV 121
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 113 RNIELKVEV 121
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 47 RNIELKVEV 55
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 47 RNIELKVEV 55
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RNIVLKVEV 9
          RNI LKVEV
Sbjct: 50 RNIELKVEV 58
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 113 RNIELKVEV 121
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RNI LKVEV
Sbjct: 113 RNIELKVEV 121
>NP_004953
          Length = 478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RNIVLKV 7
           RN+VLKV
Sbjct: 460 RNVVLKV 466
>XP_006717825
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RNIVLKV 7
           RN+VLKV
Sbjct: 459 RNVVLKV 465
>NP_004841
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RNIVLKVE 8
           RN+ LK+E
Sbjct: 790 RNLTLKIE 797
>NP_056386
          Length = 1112

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RNI+LK++
Sbjct: 1072 RNIILKLQ 1079
>NP_008893
          Length = 639

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  NIVLKVEV 9
          N++LK+EV
Sbjct: 74 NLILKLEV 81
>NP_001171570
          Length = 639

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  NIVLKVEV 9
          N++LK+EV
Sbjct: 74 NLILKLEV 81
>NP_001007089
          Length = 620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  NIVLKVEV 9
          N++LK+EV
Sbjct: 55 NLILKLEV 62
>XP_006715520
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RNI+LK++
Sbjct: 1016 RNIILKLQ 1023
>XP_005246247
          Length = 1417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RNIVLKVE 8
           RN+ LK+E
Sbjct: 790 RNLTLKIE 797
>NP_001093879
          Length = 1105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RNI+LK++
Sbjct: 1065 RNIILKLQ 1072
>NP_005742
          Length = 3907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RN+V+K+E
Sbjct: 3610 RNMVMKLE 3617
>NP_671714
          Length = 3899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RN+V+K+E
Sbjct: 3602 RNMVMKLE 3609
>NP_001248770
          Length = 1006

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNIVLKVEV 9
           RNI LK+ +
Sbjct: 697 RNIFLKISI 705
>XP_006723569
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           +N+V K+EV
Sbjct: 119 KNLVRKIEV 127
>XP_005259486
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           +N+V K+EV
Sbjct: 119 KNLVRKIEV 127
>XP_005255642
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNIVLKVEV 9
           RNI LK+ +
Sbjct: 338 RNIFLKISI 346
>XP_006715890
          Length = 3860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RN+V+K+E
Sbjct: 3563 RNMVMKLE 3570
>XP_005250160
          Length = 3939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RN+V+K+E
Sbjct: 3642 RNMVMKLE 3649
>XP_005250159
          Length = 3952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RNIVLKVE 8
            RN+V+K+E
Sbjct: 3655 RNMVMKLE 3662
>NP_001098719
          Length = 948

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNIVLKVEV 9
           RNI LK+ +
Sbjct: 697 RNIFLKISI 705
>NP_001098718
          Length = 1006

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNIVLKVEV 9
           RNI LK+ +
Sbjct: 697 RNIFLKISI 705
>NP_079056
          Length = 760

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RNIVLKVEV 9
           RNI LK+ +
Sbjct: 451 RNIFLKISI 459
>NP_001074001
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RNIVLKVE 8
          +NIVLK E
Sbjct: 82 KNIVLKFE 89
>NP_001073926
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           +N+V K+EV
Sbjct: 119 KNLVRKIEV 127
>NP_000811
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RNIVLKV 7
           RN+V+KV
Sbjct: 389 RNLVIKV 395
>NP_001137417
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RNIVLKV 7
           RN+V+KV
Sbjct: 116 RNLVIKV 122
>NP_001137418
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RNIVLKV 7
          RN+V+KV
Sbjct: 90 RNLVIKV 96
>NP_001120670
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RN++LK+ +
Sbjct: 512 RNLILKLAI 520
>NP_009198
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RN++LK+ +
Sbjct: 512 RNLILKLAI 520
>NP_001192
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RNIVLKV 7
           +N+VLKV
Sbjct: 454 KNVVLKV 460
>XP_005257055
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RN++LK+ +
Sbjct: 285 RNLILKLAI 293
>XP_005257053
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RN++LK+ +
Sbjct: 512 RNLILKLAI 520
>XP_005257052
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RNIVLKVEV 9
           RN++LK+ +
Sbjct: 512 RNLILKLAI 520
>XP_006714354
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RNIVLKV 7
           +N+VLKV
Sbjct: 421 KNVVLKV 427
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.145    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 307,934
Number of extensions: 561
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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