Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_839943                                                              16    5631
NP_003354                                                              16    7355
NP_060052                                                              16    7355
NP_955475                                                              16    7355
XP_005245372                                                           16    7355
NP_000262                                                              15    9605
NP_001268669                                                           15    9605
NP_001702                                                              15    9605
NP_001165882                                                           15    9605
NP_573403                                                              15    9605
NP_001165883                                                           15    9605
NP_001244897                                                           15    9605
NP_079411                                                              15    9605
NP_001268668                                                           15    9605
NP_620409                                                              15    9605
NP_060217                                                              15    9605
NP_877496                                                              15    9605
NP_065741                                                              15    9605
XP_005260559                                                           15    9605
XP_005260558                                                           15    9605
XP_006723918                                                           15    9605
XP_005260557                                                           15    9605
XP_005260556                                                           15    9605
XP_005260555                                                           15    9605
XP_005260554                                                           15    9605
XP_006723917                                                           15    9605
XP_005260553                                                           15    9605
XP_006722614                                                           15    9605
XP_005258412                                                           15    9605
XP_005258411                                                           15    9605
XP_005258409                                                           15    9605
XP_005258408                                                           15    9605
XP_006722613                                                           15    9605
XP_005258407                                                           15    9605
XP_005258406                                                           15    9605
XP_005258405                                                           15    9605
XP_005258404                                                           15    9605
XP_005258403                                                           15    9605
XP_006722542                                                           15    9605
XP_005258336                                                           15    9605
XP_005258335                                                           15    9605
XP_005258334                                                           15    9605
XP_006710999                                                           15    9605
XP_006710998                                                           15    9605
>NP_839943
          Length = 1631

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLYAVSLVN 9
           R+ AVSL+N
Sbjct: 524 RVLAVSLIN 532
>NP_003354
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RLYAVSLVN 9
           RL+  SLVN
Sbjct: 705 RLFTFSLVN 713
>NP_060052
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YAVSLVN 9
           YAV LVN
Sbjct: 274 YAVELVN 280
>NP_955475
          Length = 916

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RLYAVSLVN 9
           RL+  SLVN
Sbjct: 658 RLFTFSLVN 666
>XP_005245372
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YAVSLVN 9
           YAV LVN
Sbjct: 274 YAVELVN 280
>NP_000262
          Length = 1278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LYAVSLVN 9
            L AVSLVN
Sbjct: 1149 LNAVSLVN 1156
>NP_001268669
          Length = 1622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>NP_001702
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LYAVSLVN 9
           LYA+ LVN
Sbjct: 116 LYALVLVN 123
>NP_001165882
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YAVSLV+
Sbjct: 220 YAVSLVD 226
>NP_573403
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 234 YAIALIN 240
>NP_001165883
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YAVSLV+
Sbjct: 222 YAVSLVD 228
>NP_001244897
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LYAVSLVN 9
          LY+VSL N
Sbjct: 16 LYSVSLQN 23
>NP_079411
          Length = 1439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>NP_001268668
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>NP_620409
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YAVSLV+
Sbjct: 222 YAVSLVD 228
>NP_060217
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    YAVSLVN 9
            YAV L+N
Sbjct: 1754 YAVQLIN 1760
>NP_877496
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 234 YAIALIN 240
>NP_065741
          Length = 2617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    YAVSLVN 9
            YAV L+N
Sbjct: 1754 YAVQLIN 1760
>XP_005260559
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  YAVSLVN 9
          YA++L+N
Sbjct: 51 YAIALIN 57
>XP_005260558
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  YAVSLVN 9
          YA++L+N
Sbjct: 51 YAIALIN 57
>XP_006723918
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 146 YAIALIN 152
>XP_005260557
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 146 YAIALIN 152
>XP_005260556
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 146 YAIALIN 152
>XP_005260555
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 146 YAIALIN 152
>XP_005260554
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 146 YAIALIN 152
>XP_006723917
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 234 YAIALIN 240
>XP_005260553
          Length = 720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YA++L+N
Sbjct: 234 YAIALIN 240
>XP_006722614
          Length = 1589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258412
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258411
          Length = 1409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258409
          Length = 1430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258408
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_006722613
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258407
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258406
          Length = 1559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258405
          Length = 1597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258404
          Length = 1605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_005258403
          Length = 1614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LYAVSLVN 9
           +YA++LVN
Sbjct: 263 VYAMTLVN 270
>XP_006722542
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LYAVSLVN 9
            L AVSLVN
Sbjct: 1166 LNAVSLVN 1173
>XP_005258336
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LYAVSLVN 9
            L AVSLVN
Sbjct: 1149 LNAVSLVN 1156
>XP_005258335
          Length = 1295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LYAVSLVN 9
            L AVSLVN
Sbjct: 1166 LNAVSLVN 1173
>XP_005258334
          Length = 1303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LYAVSLVN 9
            L AVSLVN
Sbjct: 1166 LNAVSLVN 1173
>XP_006710999
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YAVSLV+
Sbjct: 161 YAVSLVD 167
>XP_006710998
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   YAVSLVN 9
           YAVSLV+
Sbjct: 222 YAVSLVD 228
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.138    0.357 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 344,932
Number of extensions: 584
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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