Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1935
NP_001185763                                                           18    1935
NP_055459                                                              18    1935
NP_001002811                                                           18    1935
NP_001002812                                                           18    1935
XP_006711719                                                           18    1935
XP_006711717                                                           18    1935
XP_006711716                                                           18    1935
XP_006711715                                                           18    1935
XP_006711714                                                           18    1935
XP_006711713                                                           18    1935
XP_006711712                                                           18    1935
XP_006711711                                                           18    1935
XP_006711710                                                           18    1935
XP_006711709                                                           18    1935
XP_005277503                                                           18    1935
XP_005273038                                                           18    1935
XP_006711708                                                           18    1935
XP_005277500                                                           18    1935
XP_006711707                                                           18    1935
XP_005277499                                                           18    1935
XP_006711706                                                           18    1935
XP_006711705                                                           18    1935
NP_001180197                                                           16    7355
NP_036287                                                              16    7355
NP_001180198                                                           16    7355
NP_001128244                                                           16    7355
NP_001128245                                                           16    7355
NP_003754                                                              16    7355
NP_001001433                                                           16    7355
NP_851320                                                              16    7355
XP_006723189                                                           16    7355
XP_006723188                                                           16    7355
NP_776257                                                              16    7355
NP_000470                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 895 RLTQEVLLL 903
>NP_001185763
          Length = 2362

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 829 RLTQEVLLL 837
>NP_055459
          Length = 2346

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 829 RLTQEVLLL 837
>NP_001002811
          Length = 1132

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>NP_001002812
          Length = 969

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 829 RLTQEVLLL 837
>XP_006711719
          Length = 2302

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 895 RLTQEVLLL 903
>XP_006711717
          Length = 2385

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 895 RLTQEVLLL 903
>XP_006711716
          Length = 2411

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 895 RLTQEVLLL 903
>XP_006711715
          Length = 2428

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 829 RLTQEVLLL 837
>XP_006711714
          Length = 2429

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 829 RLTQEVLLL 837
>XP_006711713
          Length = 2432

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 832 RLTQEVLLL 840
>XP_006711712
          Length = 2473

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_006711711
          Length = 2482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_006711710
          Length = 2494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 895 RLTQEVLLL 903
>XP_006711709
          Length = 2495

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           RLTQ VLLL
Sbjct: 895 RLTQEVLLL 903
>XP_005277503
          Length = 2498

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_005273038
          Length = 2509

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_006711708
          Length = 2512

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_005277500
          Length = 2525

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_006711707
          Length = 2553

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_005277499
          Length = 2561

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_006711706
          Length = 2591

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>XP_006711705
          Length = 2592

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLTQAVLLL 9
            RLTQ VLLL
Sbjct: 992  RLTQEVLLL 1000
>NP_001180197
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RLTQAVL 7
           R+TQAVL
Sbjct: 485 RITQAVL 491
>NP_036287
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RLTQAVL 7
           R+TQAVL
Sbjct: 284 RITQAVL 290
>NP_001180198
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RLTQAVL 7
           R+TQAVL
Sbjct: 431 RITQAVL 437
>NP_001128244
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  RLTQAVLLL 9
          RLT A LLL
Sbjct: 5  RLTDAFLLL 13
>NP_001128245
          Length = 308

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  RLTQAVLLL 9
          RLT A LLL
Sbjct: 5  RLTDAFLLL 13
>NP_003754
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  RLTQAVLLL 9
          RLT A LLL
Sbjct: 5  RLTDAFLLL 13
>NP_001001433
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  RLTQAVLLL 9
          RLT A LLL
Sbjct: 5  RLTDAFLLL 13
>NP_851320
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LTQAVLLL 9
           +TQ+VLLL
Sbjct: 296 MTQSVLLL 303
>XP_006723189
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RLTQAVL 7
           R+TQAVL
Sbjct: 430 RITQAVL 436
>XP_006723188
          Length = 849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RLTQAVL 7
           R+TQAVL
Sbjct: 484 RITQAVL 490
>NP_776257
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           R +QA+LLL
Sbjct: 266 RASQAILLL 274
>NP_000470
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLTQAVLLL 9
           R+T A+LLL
Sbjct: 244 RMTPALLLL 252
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.148    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 263,901
Number of extensions: 314
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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