Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001001890                                                           18    1935
NP_001745                                                              18    1935
XP_005261126                                                           18    1935
XP_005261125                                                           18    1935
NP_065386                                                              17    3301
XP_005268986                                                           17    3301
NP_776253                                                              17    4312
NP_115524                                                              17    4312
NP_001008487                                                           17    4312
NP_001008485                                                           17    4312
NP_060306                                                              17    4312
NP_001157947                                                           17    4312
XP_005269237                                                           17    4312
XP_005269236                                                           17    4312
XP_005269235                                                           17    4312
XP_006719693                                                           17    4312
XP_005269233                                                           17    4312
XP_005247622                                                           17    4312
XP_005247621                                                           17    4312
XP_006713744                                                           17    4312
XP_005247620                                                           17    4312
XP_005247619                                                           17    4312
XP_005247618                                                           17    4312
XP_005247617                                                           17    4312
XP_005247616                                                           17    4312
XP_005245126                                                           17    4312
XP_006720690                                                           16    5631
NP_116116                                                              16    7355
NP_057520                                                              16    7355
NP_776175                                                              16    7355
XP_005254368                                                           16    7355
XP_005254367                                                           16    7355
XP_006720536                                                           16    7355
XP_006726466                                                           15    9605
XP_006720284                                                           15    9605
XP_005267978                                                           15    9605
XP_005267977                                                           15    9605
XP_005267976                                                           15    9605
XP_006712969                                                           15    9605
XP_006710208                                                           15    9605
NP_001153003                                                           15    9605
NP_065887                                                              15    9605
>NP_001001890
          Length = 453

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           LSSRLSTA
Sbjct: 290 LSSRLSTA 297
>NP_001745
          Length = 480

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           LSSRLSTA
Sbjct: 317 LSSRLSTA 324
>XP_005261126
          Length = 416

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           LSSRLSTA
Sbjct: 253 LSSRLSTA 260
>XP_005261125
          Length = 468

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           LSSRLSTA
Sbjct: 305 LSSRLSTA 312
>NP_065386
          Length = 179

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   RLSSRLST 8
           RLS+RLST
Sbjct: 124 RLSNRLST 131
>XP_005268986
          Length = 179

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   RLSSRLST 8
           RLS+RLST
Sbjct: 124 RLSNRLST 131
>NP_776253
          Length = 513

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 153 LASRLSTA 160
>NP_115524
          Length = 573

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 214 LASRLSTA 221
>NP_001008487
          Length = 461

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 94  LASRLSTA 101
>NP_001008485
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>NP_060306
          Length = 487

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>NP_001157947
          Length = 370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  LSSRLSTA 9
          L+SRLSTA
Sbjct: 3  LASRLSTA 10
>XP_005269237
          Length = 527

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 214 LASRLSTA 221
>XP_005269236
          Length = 573

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 214 LASRLSTA 221
>XP_005269235
          Length = 573

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 214 LASRLSTA 221
>XP_006719693
          Length = 573

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 214 LASRLSTA 221
>XP_005269233
          Length = 573

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 214 LASRLSTA 221
>XP_005247622
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 94  LASRLSTA 101
>XP_005247621
          Length = 502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_006713744
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_005247620
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_005247619
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_005247618
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_005247617
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_005247616
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 120 LASRLSTA 127
>XP_005245126
          Length = 513

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LSSRLSTA 9
           L+SRLSTA
Sbjct: 153 LASRLSTA 160
>XP_006720690
          Length = 1245

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    LSSRLSTA 9
            LSSRLS+A
Sbjct: 1173 LSSRLSSA 1180
>NP_116116
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RLSSRLSTA 9
          RLS+RLS A
Sbjct: 24 RLSARLSGA 32
>NP_057520
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RLSSRLST 8
           R SSRLST
Sbjct: 326 RRSSRLST 333
>NP_776175
          Length = 1150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RLSSRLST 8
           RLS RLST
Sbjct: 553 RLSFRLST 560
>XP_005254368
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RLSSRLST 8
           RLS RLST
Sbjct: 553 RLSFRLST 560
>XP_005254367
          Length = 1031

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RLSSRLST 8
           RLS RLST
Sbjct: 434 RLSFRLST 441
>XP_006720536
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RLSSRLST 8
           RLS RLST
Sbjct: 475 RLSFRLST 482
>XP_006726466
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LSSRLSTA 9
            LSSRLS A
Sbjct: 1002 LSSRLSEA 1009
>XP_006720284
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 180 LSSRLSDA 187
>XP_005267978
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 195 LSSRLSDA 202
>XP_005267977
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 207 LSSRLSDA 214
>XP_005267976
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 208 LSSRLSDA 215
>XP_006712969
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    LSSRLSTA 9
            LSSRLS A
Sbjct: 1002 LSSRLSEA 1009
>XP_006710208
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 358 LSSRLSEA 365
>NP_001153003
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 195 LSSRLSDA 202
>NP_065887
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSSRLSTA 9
           LSSRLS A
Sbjct: 195 LSSRLSDA 202
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.113    0.250 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 207,667
Number of extensions: 247
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package