Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           19     665
NP_001138390                                                           19     665
NP_001138386                                                           19     665
NP_001138387                                                           19     665
NP_000132                                                              19     665
NP_075259                                                              19     665
NP_001138388                                                           19     665
NP_001138391                                                           19     665
NP_001138385                                                           19     665
NP_075418                                                              19     665
XP_006717776                                                           19     665
XP_006717775                                                           19     665
XP_006717774                                                           19     665
XP_006717773                                                           19     665
XP_006717772                                                           19     665
XP_006717771                                                           19     665
NP_001121631                                                           17    3301
XP_006721617                                                           17    3301
XP_005256773                                                           17    3301
XP_005256772                                                           17    3301
NP_001068567                                                           17    4312
NP_003717                                                              17    4312
XP_006726671                                                           17    4312
XP_005257812                                                           17    4312
NP_071397                                                              16    5631
NP_003039                                                              16    5631
XP_005276458                                                           16    5631
XP_006710877                                                           16    5631
XP_005244829                                                           16    5631
XP_005275762                                                           16    5631
NP_054859                                                              16    7355
NP_001120679                                                           16    7355
NP_065871                                                              16    7355
NP_056073                                                              16    7355
XP_006726572                                                           16    7355
XP_006726571                                                           16    7355
XP_006726570                                                           16    7355
XP_003960511                                                           16    7355
XP_005260528                                                           16    7355
XP_006717414                                                           16    7355
XP_006717082                                                           16    7355
XP_006717081                                                           16    7355
XP_006714294                                                           16    7355
XP_006712620                                                           16    7355
XP_005246688                                                           16    7355
XP_005246689                                                           16    7355
XP_001718723                                                           16    7355
XP_006710283                                                           16    7355
XP_006710282                                                           16    7355
NP_001007103                                                           15    9605
NP_115814                                                              15    9605
NP_055090                                                              15    9605
NP_463459                                                              15    9605
NP_001271236                                                           15    9605
NP_001271235                                                           15    9605
NP_001015055                                                           15    9605
NP_071918                                                              15    9605
XP_005254648                                                           15    9605
XP_005267218                                                           15    9605
XP_006715641                                                           15    9605
XP_006715640                                                           15    9605
XP_006715639                                                           15    9605
XP_005264536                                                           15    9605
XP_005264535                                                           15    9605
>NP_001138389
          Length = 705

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 334 RLSSTADTP 342
>NP_001138390
          Length = 704

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 333 RLSSTADTP 341
>NP_001138386
          Length = 709

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 338 RLSSTADTP 346
>NP_001138387
          Length = 707

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 361 RLSSTADTP 369
>NP_000132
          Length = 821

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 450 RLSSTADTP 458
>NP_075259
          Length = 822

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 451 RLSSTADTP 459
>NP_001138388
          Length = 706

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 335 RLSSTADTP 343
>NP_001138391
          Length = 680

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 362 RLSSTADTP 370
>NP_001138385
          Length = 769

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 451 RLSSTADTP 459
>NP_075418
          Length = 732

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 361 RLSSTADTP 369
>XP_006717776
          Length = 806

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 469 RLSSTADTP 477
>XP_006717775
          Length = 726

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 355 RLSSTADTP 363
>XP_006717774
          Length = 752

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 381 RLSSTADTP 389
>XP_006717773
          Length = 807

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 470 RLSSTADTP 478
>XP_006717772
          Length = 838

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 467 RLSSTADTP 475
>XP_006717771
          Length = 839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLSLTADTP 9
           RLS TADTP
Sbjct: 468 RLSSTADTP 476
>NP_001121631
          Length = 832

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           LSLTA TP
Sbjct: 807 LSLTAPTP 814
>XP_006721617
          Length = 641

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           LSLTA TP
Sbjct: 616 LSLTAPTP 623
>XP_005256773
          Length = 641

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           LSLTA TP
Sbjct: 616 LSLTAPTP 623
>XP_005256772
          Length = 803

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           LSLTA TP
Sbjct: 778 LSLTAPTP 785
>NP_001068567
          Length = 358

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSLTADTP 9
          LSLT+D P
Sbjct: 78 LSLTSDAP 85
>NP_003717
          Length = 359

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSLTADTP 9
          LSLT+D P
Sbjct: 78 LSLTSDAP 85
>XP_006726671
          Length = 353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLSLTA  P
Sbjct: 249 RLSLTAPLP 257
>XP_005257812
          Length = 341

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LSLTADTP 9
          LSLT+D P
Sbjct: 78 LSLTSDAP 85
>NP_071397
          Length = 1276

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            LSL+ DTP
Sbjct: 1238 LSLSEDTP 1245
>NP_003039
          Length = 812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           R SLTADT
Sbjct: 621 RHSLTADT 628
>XP_005276458
          Length = 263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           L LTAD+P
Sbjct: 166 LCLTADSP 173
>XP_006710877
          Length = 1276

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            LSL+ DTP
Sbjct: 1238 LSLSEDTP 1245
>XP_005244829
          Length = 1277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            LSL+ DTP
Sbjct: 1239 LSLSEDTP 1246
>XP_005275762
          Length = 263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           L LTAD+P
Sbjct: 166 LCLTADSP 173
>NP_054859
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LSLTADTP 9
           LSLT D P
Sbjct: 414 LSLTPDVP 421
>NP_001120679
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LSLTADTP 9
           LSLT D P
Sbjct: 414 LSLTPDVP 421
>NP_065871
          Length = 1659

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLSL  D+P
Sbjct: 832 RLSLCEDSP 840
>NP_056073
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RLSLTAD 7
            RLSLT+D
Sbjct: 1095 RLSLTSD 1101
>XP_006726572
          Length = 2066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           L+LTA TP
Sbjct: 774 LTLTAHTP 781
>XP_006726571
          Length = 3681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            L+LTA TP
Sbjct: 2430 LTLTAHTP 2437
>XP_006726570
          Length = 3722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            L+LTA TP
Sbjct: 2430 LTLTAHTP 2437
>XP_003960511
          Length = 3722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            L+LTA TP
Sbjct: 2430 LTLTAHTP 2437
>XP_005260528
          Length = 956

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLSL  D+P
Sbjct: 129 RLSLCEDSP 137
>XP_006717414
          Length = 5100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            L+LTA TP
Sbjct: 3808 LTLTAHTP 3815
>XP_006717082
          Length = 1151

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RLSLTAD 7
            RLSLT+D
Sbjct: 1027 RLSLTSD 1033
>XP_006717081
          Length = 1209

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RLSLTAD 7
            RLSLT+D
Sbjct: 1085 RLSLTSD 1091
>XP_006714294
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RLSLTADTP 9
          R+SLT D P
Sbjct: 17 RVSLTKDGP 25
>XP_006712620
          Length = 932

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LSLTADTP 9
           LSLT D P
Sbjct: 414 LSLTPDVP 421
>XP_005246688
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LSLTADTP 9
           LSLT D P
Sbjct: 414 LSLTPDVP 421
>XP_005246689
          Length = 954

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LSLTADTP 9
           LSLT D P
Sbjct: 414 LSLTPDVP 421
>XP_001718723
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    SLTADTP 9
            SLTAD P
Sbjct: 1078 SLTADIP 1084
>XP_006710283
          Length = 2066

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LSLTADTP 9
           L+LTA TP
Sbjct: 774 LTLTAHTP 781
>XP_006710282
          Length = 2621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LSLTADTP 9
            L+LTA TP
Sbjct: 1329 LTLTAHTP 1336
>NP_001007103
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           +LSL ADT
Sbjct: 151 KLSLKADT 158
>NP_115814
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           +LSL ADT
Sbjct: 176 KLSLKADT 183
>NP_055090
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLS+  D+P
Sbjct: 526 RLSIQTDSP 534
>NP_463459
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLS+  D+P
Sbjct: 541 RLSIQTDSP 549
>NP_001271236
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLS  ++TP
Sbjct: 541 RLSFASETP 549
>NP_001271235
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLSLTADTP 9
           RLS  ++TP
Sbjct: 498 RLSFASETP 506
>NP_001015055
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RLSLTADTP 9
          RLSL +D P
Sbjct: 28 RLSLFSDLP 36
>NP_071918
          Length = 1883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RLSLTADTP 9
            RLS  ++TP
Sbjct: 1313 RLSFASETP 1321
>XP_005254648
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    RLSLTADTP 9
            RLS  ++TP
Sbjct: 1336 RLSFASETP 1344
>XP_005267218
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           +LSL ADT
Sbjct: 176 KLSLKADT 183
>XP_006715641
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           +LSL ADT
Sbjct: 176 KLSLKADT 183
>XP_006715640
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           +LSL ADT
Sbjct: 176 KLSLKADT 183
>XP_006715639
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLSLTADT 8
           +LSL ADT
Sbjct: 211 KLSLKADT 218
>XP_005264536
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RLSLTADTP 9
          RLSL +D P
Sbjct: 28 RLSLFSDLP 36
>XP_005264535
          Length = 490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RLSLTADTP 9
          RLSL +D P
Sbjct: 28 RLSLFSDLP 36
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.125    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 473,048
Number of extensions: 887
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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