Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005912                                                              18    1482
XP_005248577                                                           18    1482
XP_005248576                                                           18    1482
NP_570629                                                              17    3301
NP_001034439                                                           17    3301
NP_001927                                                              17    3301
NP_001277181                                                           17    3301
XP_006715935                                                           17    3301
XP_006715934                                                           17    3301
XP_005263378                                                           17    3301
NP_003719                                                              17    3301
NP_060064                                                              17    3301
NP_055747                                                              16    5631
XP_006716351                                                           16    5631
XP_005247294                                                           16    5631
XP_005247293                                                           16    5631
XP_005247292                                                           16    5631
XP_005247291                                                           16    5631
XP_005247290                                                           16    5631
XP_006713603                                                           16    5631
XP_005247289                                                           16    5631
NP_543148                                                              16    5631
NP_001136105                                                           16    7355
NP_000704                                                              16    7355
NP_055123                                                              16    7355
NP_001077059                                                           16    7355
NP_003326                                                              16    7355
NP_001238784                                                           16    7355
NP_001238780                                                           16    7355
NP_001238781                                                           16    7355
NP_001238782                                                           16    7355
XP_005256637                                                           16    7355
XP_005256636                                                           16    7355
XP_005265487                                                           16    7355
XP_006713384                                                           16    7355
XP_006712099                                                           16    7355
XP_005264439                                                           16    7355
XP_005264438                                                           16    7355
NP_060197                                                              16    7355
NP_001258825                                                           15    9605
NP_001258824                                                           15    9605
NP_079426                                                              15    9605
NP_056355                                                              15    9605
NP_703143                                                              15    9605
NP_057340                                                              15    9605
XP_006720533                                                           15    9605
XP_006720532                                                           15    9605
XP_005254354                                                           15    9605
XP_006711619                                                           15    9605
XP_006711618                                                           15    9605
NP_005584                                                              15    9605
>NP_005912
          Length = 1512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLRIAVFGA 9
            RLRIA FGA
Sbjct: 1383 RLRIADFGA 1391
>XP_005248577
          Length = 1349

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLRIAVFGA 9
            RLRIA FGA
Sbjct: 1220 RLRIADFGA 1228
>XP_005248576
          Length = 1375

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLRIAVFGA 9
            RLRIA FGA
Sbjct: 1246 RLRIADFGA 1254
>NP_570629
          Length = 865

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLRIAVFG 8
           R R+AVFG
Sbjct: 703 RTRVAVFG 710
>NP_001034439
          Length = 801

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLRIAVFG 8
           R R+AVFG
Sbjct: 639 RTRVAVFG 646
>NP_001927
          Length = 803

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLRIAVFG 8
           R R+AVFG
Sbjct: 641 RTRVAVFG 648
>NP_001277181
          Length = 758

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLRIAVFG 8
           R R+AVFG
Sbjct: 596 RTRVAVFG 603
>XP_006715935
          Length = 804

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLRIAVFG 8
           R R+AVFG
Sbjct: 642 RTRVAVFG 649
>XP_006715934
          Length = 804

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLRIAVFG 8
           R R+AVFG
Sbjct: 642 RTRVAVFG 649
>XP_005263378
          Length = 950

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLRIAVFG 8
           RL++A+FG
Sbjct: 700 RLKLAIFG 707
>NP_003719
          Length = 931

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLRIAVFG 8
           RL++A+FG
Sbjct: 681 RLKLAIFG 688
>NP_060064
          Length = 199

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  RIAVFGA 9
          R+AVFGA
Sbjct: 9  RVAVFGA 15
>NP_055747
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_006716351
          Length = 865

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLRIAVFG 8
           +L++AVFG
Sbjct: 602 QLKVAVFG 609
>XP_005247294
          Length = 671

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 101 LRITVFGS 108
>XP_005247293
          Length = 814

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247292
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247291
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 253 LRITVFGS 260
>XP_005247290
          Length = 834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 273 LRITVFGS 280
>XP_006713603
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 273 LRITVFGS 280
>XP_005247289
          Length = 843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LRI VFG+
Sbjct: 273 LRITVFGS 280
>NP_543148
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLRIAVFG 8
           +L++AVFG
Sbjct: 690 QLKVAVFG 697
>NP_001136105
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>NP_000704
          Length = 206

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RIAVFGA 9
          +IA+FGA
Sbjct: 5  KIAIFGA 11
>NP_055123
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>NP_001077059
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLRIAVFGA 9
           RL++  FGA
Sbjct: 303 RLKVLAFGA 311
>NP_003326
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RIAVFGA 9
           +IAVFGA
Sbjct: 418 QIAVFGA 424
>NP_001238784
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>NP_001238780
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>NP_001238781
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>NP_001238782
          Length = 494

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 131 LRVVVFGS 138
>XP_005256637
          Length = 879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>XP_005256636
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+ VFG+
Sbjct: 517 LRVVVFGS 524
>XP_005265487
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RIAVFGA 9
           +IAVFGA
Sbjct: 418 QIAVFGA 424
>XP_006713384
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RIAVFGA 9
           +IAVFGA
Sbjct: 418 QIAVFGA 424
>XP_006712099
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLRIAVFGA 9
           RL++  FGA
Sbjct: 303 RLKVLAFGA 311
>XP_005264439
          Length = 715

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLRIAVFGA 9
           RL++  FGA
Sbjct: 348 RLKVLAFGA 356
>XP_005264438
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLRIAVFGA 9
           RL++  FGA
Sbjct: 348 RLKVLAFGA 356
>NP_060197
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RLRIAVFGA 9
           RL++  FGA
Sbjct: 348 RLKVLAFGA 356
>NP_001258825
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+A FGA
Sbjct: 298 LRLADFGA 305
>NP_001258824
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+A FGA
Sbjct: 346 LRLADFGA 353
>NP_079426
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+A FGA
Sbjct: 428 LRLADFGA 435
>NP_056355
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LRIAVFG 8
            LR+A+FG
Sbjct: 1244 LRLALFG 1250
>NP_703143
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RLRIAVF 7
           RLR AVF
Sbjct: 166 RLRFAVF 172
>NP_057340
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  LRIAVFG 8
          LR+A+FG
Sbjct: 11 LRLALFG 17
>XP_006720533
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LRIAVFG 8
           LR+A+FG
Sbjct: 949 LRLALFG 955
>XP_006720532
          Length = 1333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LRIAVFG 8
            LR+A+FG
Sbjct: 1184 LRLALFG 1190
>XP_005254354
          Length = 1393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LRIAVFG 8
            LR+A+FG
Sbjct: 1244 LRLALFG 1250
>XP_006711619
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+A FGA
Sbjct: 379 LRLADFGA 386
>XP_006711618
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRIAVFGA 9
           LR+A FGA
Sbjct: 428 LRLADFGA 435
>NP_005584
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  RIAVFGA 9
          R+A FGA
Sbjct: 35 RVAAFGA 41
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.157    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 350,482
Number of extensions: 504
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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