Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              17    3301
NP_001182612                                                           17    3301
NP_001182613                                                           17    3301
NP_001139395                                                           17    4312
NP_065894                                                              17    4312
XP_005254476                                                           17    4312
XP_005254474                                                           17    4312
NP_001138502                                                           16    5631
NP_037466                                                              16    5631
NP_068806                                                              16    5631
XP_006726572                                                           16    5631
XP_006726571                                                           16    5631
XP_006726570                                                           16    5631
XP_003960511                                                           16    5631
XP_006717414                                                           16    5631
XP_006710283                                                           16    5631
XP_006710282                                                           16    5631
NP_001082                                                              16    7355
NP_001259001                                                           16    7355
NP_569056                                                              16    7355
NP_001193809                                                           16    7355
NP_001158051                                                           16    7355
XP_006726675                                                           16    7355
XP_005250024                                                           16    7355
XP_006715981                                                           16    7355
XP_006711061                                                           16    7355
XP_006711060                                                           16    7355
XP_005244868                                                           16    7355
XP_003119848                                                           16    7355
NP_001161850                                                           16    7355
NP_005520                                                              15    9605
NP_006280                                                              15    9605
NP_001269714                                                           15    9605
NP_055874                                                              15    9605
NP_001269712                                                           15    9605
NP_001269713                                                           15    9605
NP_008966                                                              15    9605
NP_444504                                                              15    9605
NP_060476                                                              15    9605
NP_079335                                                              15    9605
NP_001269711                                                           15    9605
XP_005261738                                                           15    9605
XP_005261735                                                           15    9605
XP_006721688                                                           15    9605
XP_006720784                                                           15    9605
XP_006720783                                                           15    9605
XP_006720782                                                           15    9605
XP_006720781                                                           15    9605
XP_005254772                                                           15    9605
XP_005254771                                                           15    9605
XP_006720780                                                           15    9605
XP_005254769                                                           15    9605
XP_005254770                                                           15    9605
XP_005254765                                                           15    9605
XP_005254767                                                           15    9605
XP_006720779                                                           15    9605
XP_005254768                                                           15    9605
XP_005254764                                                           15    9605
XP_006716915                                                           15    9605
XP_005251621                                                           15    9605
XP_006715631                                                           15    9605
XP_006710661                                                           15    9605
XP_005245920                                                           15    9605
XP_006710660                                                           15    9605
XP_006710659                                                           15    9605
XP_006710658                                                           15    9605
XP_006710657                                                           15    9605
XP_006710372                                                           15    9605
XP_005270458                                                           15    9605
XP_005270457                                                           15    9605
XP_006710092                                                           15    9605
NP_005005                                                              15    9605
>NP_004295
          Length = 1620

 Score = 16.9 bits (32), Expect =  3301
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1   RLENN-SVLG 9
           RLENN SVLG
Sbjct: 860 RLENNSSVLG 869
>NP_001182612
          Length = 850

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RLENNSVLG 9
           RLENN  +G
Sbjct: 354 RLENNEEMG 362
>NP_001182613
          Length = 850

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RLENNSVLG 9
           RLENN  +G
Sbjct: 354 RLENNEEMG 362
>NP_001139395
          Length = 1154

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ENNSVLG 9
           ENN++LG
Sbjct: 786 ENNTILG 792
>NP_065894
          Length = 1400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ENNSVLG 9
            ENN++LG
Sbjct: 1032 ENNTILG 1038
>XP_005254476
          Length = 1400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ENNSVLG 9
            ENN++LG
Sbjct: 1032 ENNTILG 1038
>XP_005254474
          Length = 1406

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ENNSVLG 9
            ENN++LG
Sbjct: 1038 ENNTILG 1044
>NP_001138502
          Length = 1692

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LENNSVL 8
           +ENNSVL
Sbjct: 218 VENNSVL 224
>NP_037466
          Length = 387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLENNSVLG 9
           R+EN +VLG
Sbjct: 346 RMENVTVLG 354
>NP_068806
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLENNSVLG 9
           R+EN +VLG
Sbjct: 319 RMENVTVLG 327
>XP_006726572
          Length = 2066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RLENNS 6
           RLENNS
Sbjct: 534 RLENNS 539
>XP_006726571
          Length = 3681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RLENNS 6
            RLENNS
Sbjct: 2190 RLENNS 2195
>XP_006726570
          Length = 3722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RLENNS 6
            RLENNS
Sbjct: 2190 RLENNS 2195
>XP_003960511
          Length = 3722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RLENNS 6
            RLENNS
Sbjct: 2190 RLENNS 2195
>XP_006717414
          Length = 5100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RLENNS 6
            RLENNS
Sbjct: 3568 RLENNS 3573
>XP_006710283
          Length = 2066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RLENNS 6
           RLENNS
Sbjct: 534 RLENNS 539
>XP_006710282
          Length = 2621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RLENNS 6
            RLENNS
Sbjct: 1089 RLENNS 1094
>NP_001082
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLENNSVL 8
           RLE N+VL
Sbjct: 311 RLEGNAVL 318
>NP_001259001
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLENNSVL 8
           RLE N+VL
Sbjct: 311 RLEGNAVL 318
>NP_569056
          Length = 912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  ENNSVL 8
          ENNSVL
Sbjct: 17 ENNSVL 22
>NP_001193809
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  ENNSVL 8
          ENNSVL
Sbjct: 17 ENNSVL 22
>NP_001158051
          Length = 167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RLENNSVLG 9
           +L NN+V+G
Sbjct: 132 KLPNNTVVG 140
>XP_006726675
          Length = 167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RLENNSVLG 9
           +L NN+V+G
Sbjct: 132 KLPNNTVVG 140
>XP_005250024
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLENNSVL 8
           RLE N+VL
Sbjct: 311 RLEGNAVL 318
>XP_006715981
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RLENNSVL 8
           RLE N+VL
Sbjct: 311 RLEGNAVL 318
>XP_006711061
          Length = 1553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RLENNSVL 8
            +L+NNS+L
Sbjct: 1282 KLQNNSLL 1289
>XP_006711060
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RLENNSVL 8
            +L+NNS+L
Sbjct: 1324 KLQNNSLL 1331
>XP_005244868
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RLENNSVL 8
            +L+NNS+L
Sbjct: 1368 KLQNNSLL 1375
>XP_003119848
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           +L+NNS+L
Sbjct: 244 KLQNNSLL 251
>NP_001161850
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RLENNSVL 8
          R+ENN+ L
Sbjct: 35 RIENNNTL 42
>NP_005520
          Length = 4391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3620 RLENNMLM 3627
>NP_006280
          Length = 2541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1397 MENSKVLG 1404
>NP_001269714
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 247 IEDNKVLG 254
>NP_055874
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>NP_001269712
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 107 IEDNKVLG 114
>NP_001269713
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 107 IEDNKVLG 114
>NP_008966
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           L+NNS+ G
Sbjct: 220 LDNNSIEG 227
>NP_444504
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           R+E+NS+L
Sbjct: 345 RIEDNSLL 352
>NP_060476
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 247 IEDNKVLG 254
>NP_079335
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           RLE+N+V+
Sbjct: 470 RLESNAVI 477
>NP_001269711
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 133 IEDNKVLG 140
>XP_005261738
          Length = 244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 115 IEDNKVLG 122
>XP_005261735
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LENNSVLG 9
           +E+N VLG
Sbjct: 115 IEDNKVLG 122
>XP_006721688
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LENNSVL 8
           LE+NSVL
Sbjct: 116 LEDNSVL 122
>XP_006720784
          Length = 2502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_006720783
          Length = 2512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1354 MENSKVLG 1361
>XP_006720782
          Length = 2517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_006720781
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254772
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254771
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_006720780
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254769
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254770
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254765
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254767
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_006720779
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254768
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_005254764
          Length = 2557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1399 MENSKVLG 1406
>XP_006716915
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1397 MENSKVLG 1404
>XP_005251621
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LENNSVLG 9
            +EN+ VLG
Sbjct: 1397 MENSKVLG 1404
>XP_006715631
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           RLE+N+V+
Sbjct: 403 RLESNAVI 410
>XP_006710661
          Length = 4057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3803 RLENNMLM 3810
>XP_005245920
          Length = 4392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3621 RLENNMLM 3628
>XP_006710660
          Length = 4397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3620 RLENNMLM 3627
>XP_006710659
          Length = 4556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3779 RLENNMLM 3786
>XP_006710658
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3786 RLENNMLM 3793
>XP_006710657
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    RLENNSVL 8
            RLENN ++
Sbjct: 3802 RLENNMLM 3809
>XP_006710372
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           R+E+NS+L
Sbjct: 178 RIEDNSLL 185
>XP_005270458
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           R+E+NS+L
Sbjct: 303 RIEDNSLL 310
>XP_005270457
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RLENNSVL 8
           R+E+NS+L
Sbjct: 345 RIEDNSLL 352
>XP_006710092
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LENNSVL 8
           LE+NSVL
Sbjct: 116 LEDNSVL 122
>NP_005005
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LENNSV 7
           LENNS+
Sbjct: 240 LENNSI 245
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.132    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 609,417
Number of extensions: 1290
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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