Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     665
NP_001035957                                                           19     665
XP_006721990                                                           19     665
XP_006721989                                                           19     665
XP_005258041                                                           19     665
XP_006721988                                                           19     665
XP_006721987                                                           19     665
XP_006721986                                                           19     665
XP_005258040                                                           19     665
XP_006721985                                                           19     665
NP_001271175                                                           17    2528
NP_056371                                                              17    2528
NP_001271176                                                           17    2528
NP_001271174                                                           17    2528
XP_005267576                                                           17    2528
XP_006720175                                                           17    2528
XP_006720174                                                           17    2528
XP_005267573                                                           17    2528
XP_006720173                                                           17    2528
XP_006720172                                                           17    2528
XP_005267571                                                           17    2528
XP_005256857                                                           17    4312
NP_079222                                                              16    7355
XP_005256222                                                           16    7355
XP_005256221                                                           16    7355
XP_005256220                                                           16    7355
XP_005256217                                                           16    7355
XP_005256219                                                           16    7355
XP_005256218                                                           16    7355
XP_005256216                                                           16    7355
XP_006721339                                                           16    7355
XP_005256215                                                           16    7355
XP_005256214                                                           16    7355
XP_006721338                                                           16    7355
XP_005256213                                                           16    7355
NP_001009899                                                           15    9605
NP_001229697                                                           15    9605
NP_001229696                                                           15    9605
NP_056255                                                              15    9605
XP_006726478                                                           15    9605
XP_005266968                                                           15    9605
XP_005266967                                                           15    9605
XP_005266964                                                           15    9605
XP_006714496                                                           15    9605
XP_005247266                                                           15    9605
XP_005247265                                                           15    9605
XP_006710224                                                           15    9605



>NP_000258
          Length = 2818

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2573 RKVSVSESN 2581





>NP_001035957
          Length = 2839

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2594 RKVSVSESN 2602





>XP_006721990
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2604 RKVSVSESN 2612





>XP_006721989
          Length = 2823

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2604 RKVSVSESN 2612





>XP_005258041
          Length = 2836

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2573 RKVSVSESN 2581





>XP_006721988
          Length = 2846

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2583 RKVSVSESN 2591





>XP_006721987
          Length = 2849

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2604 RKVSVSESN 2612





>XP_006721986
          Length = 2854

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2591 RKVSVSESN 2599





>XP_005258040
          Length = 2857

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2594 RKVSVSESN 2602





>XP_006721985
          Length = 2867

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RKVSVSQSN 9
            RKVSVS+SN
Sbjct: 2604 RKVSVSESN 2612





>NP_001271175
          Length = 1782

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>NP_056371
          Length = 1804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>NP_001271176
          Length = 1803

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>NP_001271174
          Length = 1783

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_005267576
          Length = 1782

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_006720175
          Length = 1783

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_006720174
          Length = 1803

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_005267573
          Length = 1804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_006720173
          Length = 1804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_006720172
          Length = 1804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_005267571
          Length = 1804

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   RKVSVSQSN 9
           RK+S+S+SN
Sbjct: 427 RKISLSKSN 435





>XP_005256857
          Length = 246

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   KVSVSQSN 9
           KVSV QSN
Sbjct: 236 KVSVPQSN 243





>NP_079222
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256222
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256221
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256220
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256217
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256219
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256218
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_005256216
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 120 KKVGISQEN 128





>XP_006721339
          Length = 260

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 126 KKVGISQEN 134





>XP_005256215
          Length = 260

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 126 KKVGISQEN 134





>XP_005256214
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 133 KKVGISQEN 141





>XP_006721338
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 134 KKVGISQEN 142





>XP_005256213
          Length = 300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           +KV +SQ N
Sbjct: 166 KKVGISQEN 174





>NP_001009899
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSVSQSN 9
           VSVSQ+N
Sbjct: 851 VSVSQAN 857





>NP_001229697
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           RK+++ Q N
Sbjct: 520 RKITIGQGN 528





>NP_001229696
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           RK+++ Q N
Sbjct: 586 RKITIGQGN 594





>NP_056255
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           RK+++ Q N
Sbjct: 585 RKITIGQGN 593





>XP_006726478
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RKVSVSQSN 9
           R+VS SQS+
Sbjct: 262 RRVSFSQSS 270





>XP_005266968
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           RK+++ Q N
Sbjct: 586 RKITIGQGN 594





>XP_005266967
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           RK+++ Q N
Sbjct: 586 RKITIGQGN 594





>XP_005266964
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   RKVSVSQSN 9
           RK+++ Q N
Sbjct: 585 RKITIGQGN 593





>XP_006714496
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RKVSVSQSN 9
           R+VS SQS+
Sbjct: 262 RRVSFSQSS 270





>XP_005247266
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSVSQSN 9
           VSVSQ+N
Sbjct: 795 VSVSQAN 801





>XP_005247265
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSVSQSN 9
           VSVSQ+N
Sbjct: 817 VSVSQAN 823





>XP_006710224
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RKVSVSQSN 9
           R+VS SQS+
Sbjct: 262 RRVSFSQSS 270





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.102    0.222 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 242,237
Number of extensions: 273
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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