Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           19     665
NP_001257437                                                           19     665
NP_006281                                                              19     665
XP_005267176                                                           19     665
NP_055826                                                              16    7355
NP_001185879                                                           16    7355
NP_005449                                                              16    7355
XP_005252373                                                           16    7355
NP_003909                                                              15    9605
NP_001171632                                                           15    9605
NP_001073324                                                           15    9605
NP_001171631                                                           15    9605
NP_004749                                                              15    9605
NP_077729                                                              15    9605
NP_001248764                                                           15    9605
XP_005274679                                                           15    9605
XP_005274678                                                           15    9605
XP_006724585                                                           15    9605
XP_006724584                                                           15    9605
XP_005274676                                                           15    9605
XP_005274674                                                           15    9605
XP_005274675                                                           15    9605
XP_006722241                                                           15    9605
XP_006722240                                                           15    9605
XP_006722238                                                           15    9605
XP_005257864                                                           15    9605
XP_006722237                                                           15    9605
XP_006722236                                                           15    9605
>NP_001257436
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RKLVVLKTN 9
          RKLV LKTN
Sbjct: 90 RKLVALKTN 98
>NP_001257437
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RKLVVLKTN 9
          RKLV LKTN
Sbjct: 90 RKLVALKTN 98
>NP_006281
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RKLVVLKTN 9
          RKLV LKTN
Sbjct: 90 RKLVALKTN 98
>XP_005267176
          Length = 790

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RKLVVLKTN 9
          RKLV LKTN
Sbjct: 90 RKLVALKTN 98
>NP_055826
          Length = 1858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RKLVVLKTN 9
            +KL VL+TN
Sbjct: 1517 KKLPVLETN 1525
>NP_001185879
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RKLVVLKTN 9
            +KL VL+TN
Sbjct: 1539 KKLPVLETN 1547
>NP_005449
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLVVLKTN 9
           KL+ L+TN
Sbjct: 743 KLITLRTN 750
>XP_005252373
          Length = 683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLVVLKTN 9
           KL+ L+TN
Sbjct: 485 KLITLRTN 492
>NP_003909
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 66 RKLVVLIT 73
>NP_001171632
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 66 RKLVVLIT 73
>NP_001073324
          Length = 470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 35 RKLVVLIT 42
>NP_001171631
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 35 RKLVVLIT 42
>NP_004749
          Length = 1857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 795 RRLVVLK 801
>NP_077729
          Length = 1797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 735 RRLVVLK 741
>NP_001248764
          Length = 1848

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 795 RRLVVLK 801
>XP_005274679
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 35 RKLVVLIT 42
>XP_005274678
          Length = 489

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 35 RKLVVLIT 42
>XP_006724585
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 64 RKLVVLIT 71
>XP_006724584
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 66 RKLVVLIT 73
>XP_005274676
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 66 RKLVVLIT 73
>XP_005274674
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 66 RKLVVLIT 73
>XP_005274675
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  RKLVVLKT 8
          RKLVVL T
Sbjct: 66 RKLVVLIT 73
>XP_006722241
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 355 RRLVVLK 361
>XP_006722240
          Length = 1467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 355 RRLVVLK 361
>XP_006722238
          Length = 1847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 735 RRLVVLK 741
>XP_005257864
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 795 RRLVVLK 801
>XP_006722237
          Length = 1900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 788 RRLVVLK 794
>XP_006722236
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RKLVVLK 7
           R+LVVLK
Sbjct: 795 RRLVVLK 801
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.136    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,403
Number of extensions: 521
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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