Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055668                                                              17    3301
XP_006721677                                                           17    3301
XP_006721676                                                           17    3301
NP_001091979                                                           17    3301
NP_056475                                                              17    4312
NP_079239                                                              17    4312
NP_001128523                                                           17    4312
NP_065991                                                              17    4312
NP_001139681                                                           17    4312
NP_001230713                                                           17    4312
NP_001137311                                                           17    4312
NP_002590                                                              17    4312
NP_001243496                                                           17    4312
NP_000691                                                              17    4312
NP_005679                                                              17    4312
NP_000741                                                              17    4312
NP_001138740                                                           17    4312
NP_542141                                                              17    4312
NP_112598                                                              17    4312
XP_005260338                                                           17    4312
XP_005274097                                                           17    4312
XP_006715959                                                           17    4312
XP_005249911                                                           17    4312
XP_005249910                                                           17    4312
XP_005247116                                                           17    4312
XP_005247115                                                           17    4312
NP_570115                                                              16    5631
NP_061738                                                              16    5631
NP_114398                                                              16    5631
NP_001253981                                                           16    5631
XP_005258187                                                           16    5631
XP_005257983                                                           16    5631
NP_001073678                                                           16    5631
NP_775259                                                              16    5631
NP_001028748                                                           16    5631
NP_620598                                                              16    7355
NP_620599                                                              16    7355
NP_004348                                                              16    7355
NP_001034579                                                           16    7355
NP_037365                                                              16    7355
NP_005100                                                              16    7355
NP_689607                                                              16    7355
NP_002449                                                              16    7355
NP_891992                                                              16    7355
XP_005247176                                                           16    7355
XP_006713561                                                           16    7355
XP_005265695                                                           16    7355
XP_005246523                                                           16    7355
XP_005246522                                                           16    7355
NP_001004745                                                           16    7355
NP_001004746                                                           16    7355
NP_060661                                                              15    9605
NP_001123989                                                           15    9605
NP_001013454                                                           15    9605
NP_066949                                                              15    9605
NP_005754                                                              15    9605
NP_004362                                                              15    9605
NP_001091868                                                           15    9605
NP_001009905                                                           15    9605
NP_002423                                                              15    9605
XP_006726603                                                           15    9605
XP_006725352                                                           15    9605
XP_006725215                                                           15    9605
XP_005261667                                                           15    9605
XP_006722336                                                           15    9605
XP_006722335                                                           15    9605
XP_005256248                                                           15    9605
XP_005266498                                                           15    9605
XP_006719237                                                           15    9605
NP_113678                                                              15    9605
>NP_055668
          Length = 1051

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LVALCGA 9
          ++ALCGA
Sbjct: 40 IIALCGA 46
>XP_006721677
          Length = 1028

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LVALCGA 9
          ++ALCGA
Sbjct: 40 IIALCGA 46
>XP_006721676
          Length = 1073

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LVALCGA 9
          ++ALCGA
Sbjct: 40 IIALCGA 46
>NP_001091979
          Length = 1006

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LVALCGA 9
          ++ALCGA
Sbjct: 40 IIALCGA 46
>NP_056475
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   KLVALCG 8
           KLVA CG
Sbjct: 170 KLVAACG 176
>NP_079239
          Length = 718

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RKLVALC 7
          RKL ALC
Sbjct: 57 RKLAALC 63
>NP_001128523
          Length = 738

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           +KL+ LCG
Sbjct: 133 QKLIRLCG 140
>NP_065991
          Length = 765

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           +KL+ LCG
Sbjct: 133 QKLIRLCG 140
>NP_001139681
          Length = 932

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           RK++ LCG
Sbjct: 219 RKILQLCG 226
>NP_001230713
          Length = 920

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           RK++ LCG
Sbjct: 207 RKILQLCG 214
>NP_001137311
          Length = 934

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           RK++ LCG
Sbjct: 221 RKILQLCG 228
>NP_002590
          Length = 941

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           RK++ LCG
Sbjct: 228 RKILQLCG 235
>NP_001243496
          Length = 231

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LVALCG 8
          LVALCG
Sbjct: 12 LVALCG 17
>NP_000691
          Length = 346

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LVALCG 8
           LVALCG
Sbjct: 339 LVALCG 344
>NP_005679
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLVALCGA 9
           KLV +CG+
Sbjct: 589 KLVGICGS 596
>NP_000741
          Length = 498

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LVALCG 8
          LVALCG
Sbjct: 12 LVALCG 17
>NP_001138740
          Length = 392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           R LVA+CG
Sbjct: 100 RVLVAVCG 107
>NP_542141
          Length = 249

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KLVALCG 8
          KLV LCG
Sbjct: 6  KLVLLCG 12
>NP_112598
          Length = 5088

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RKLVALC 7
            R+LVALC
Sbjct: 1484 RELVALC 1490
>XP_005260338
          Length = 249

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  KLVALCG 8
          KLV LCG
Sbjct: 6  KLVLLCG 12
>XP_005274097
          Length = 940

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           RK++ LCG
Sbjct: 227 RKILQLCG 234
>XP_006715959
          Length = 385

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           R LVA+CG
Sbjct: 100 RVLVAVCG 107
>XP_005249911
          Length = 672

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RKLVALC 7
          RKL ALC
Sbjct: 57 RKLAALC 63
>XP_005249910
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RKLVALC 7
          RKL ALC
Sbjct: 57 RKLAALC 63
>XP_005247116
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLVALCGA 9
           KLV +CG+
Sbjct: 589 KLVGICGS 596
>XP_005247115
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KLVALCGA 9
           KLV +CG+
Sbjct: 589 KLVGICGS 596
>NP_570115
          Length = 306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           R+LVA CG
Sbjct: 175 RELVAECG 182
>NP_061738
          Length = 932

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RKLVALC 7
          RKLV LC
Sbjct: 11 RKLVLLC 17
>NP_114398
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RKLVALC 7
          RKLV LC
Sbjct: 11 RKLVLLC 17
>NP_001253981
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVALCGA 9
           +VALCG+
Sbjct: 426 MVALCGS 432
>XP_005258187
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LVALCG 8
          L+ALCG
Sbjct: 54 LIALCG 59
>XP_005257983
          Length = 850

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVALCGA 9
           +VALCG+
Sbjct: 426 MVALCGS 432
>NP_001073678
          Length = 621

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LVALCG 8
          L+ALCG
Sbjct: 54 LIALCG 59
>NP_775259
          Length = 931

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVALCGA 9
           +VALCG+
Sbjct: 426 MVALCGS 432
>NP_001028748
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LVALCGA 9
           +VALCG+
Sbjct: 426 MVALCGS 432
>NP_620598
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           + +VALCG
Sbjct: 186 KTVVALCG 193
>NP_620599
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           + +VALCG
Sbjct: 186 KTVVALCG 193
>NP_004348
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           + +VALCG
Sbjct: 186 KTVVALCG 193
>NP_001034579
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RKLVALCG 8
           + +VALCG
Sbjct: 186 KTVVALCG 193
>NP_037365
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RKLVALC 7
           RKL++LC
Sbjct: 311 RKLLSLC 317
>NP_005100
          Length = 527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   RKLVALC 7
           RK+++LC
Sbjct: 265 RKMISLC 271
>NP_689607
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KLVALC 7
           KL+ALC
Sbjct: 637 KLIALC 642
>NP_002449
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    LVALCGA 9
            L+A+CG+
Sbjct: 1285 LIAICGS 1291
>NP_891992
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RKLVALCG 8
          RK++A CG
Sbjct: 17 RKVLAKCG 24
>XP_005247176
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KLVALC 7
           KL+ALC
Sbjct: 491 KLIALC 496
>XP_006713561
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KLVALC 7
           KL+ALC
Sbjct: 590 KLIALC 595
>XP_005265695
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   RKLVALC 7
           RK+++LC
Sbjct: 198 RKMISLC 204
>XP_005246523
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RKLVALC 7
           RKL++LC
Sbjct: 147 RKLLSLC 153
>XP_005246522
          Length = 524

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RKLVALC 7
           RKL++LC
Sbjct: 311 RKLLSLC 317
>NP_001004745
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           RK+ + CGA
Sbjct: 247 RKVFSTCGA 255
>NP_001004746
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           RK+ + CGA
Sbjct: 274 RKVFSTCGA 282
>NP_060661
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  RKLVALCG 8
          +KL  LCG
Sbjct: 66 KKLEGLCG 73
>NP_001123989
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           + LVA CG+
Sbjct: 242 KPLVATCGS 250
>NP_001013454
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           + LVA CG+
Sbjct: 242 KPLVATCGS 250
>NP_066949
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           + LVA CG+
Sbjct: 262 KPLVATCGS 270
>NP_005754
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KLVALC 7
           KLVA+C
Sbjct: 348 KLVAIC 353
>NP_004362
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RKLVALC 7
           RKL ALC
Sbjct: 516 RKLDALC 522
>NP_001091868
          Length = 1233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RKLVALC 7
           RKL ALC
Sbjct: 525 RKLDALC 531
>NP_001009905
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RKLVALC 7
           RK+VA C
Sbjct: 286 RKVVAFC 292
>NP_002423
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           RKL  +CG+
Sbjct: 379 RKLKLVCGS 387
>XP_006726603
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    LVALCG 8
            L+A+CG
Sbjct: 1059 LIAICG 1064
>XP_006725352
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RKLVALC 7
           RK+VA C
Sbjct: 271 RKVVAFC 277
>XP_006725215
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    LVALCG 8
            L+A+CG
Sbjct: 1059 LIAICG 1064
>XP_005261667
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           + LVA CG+
Sbjct: 242 KPLVATCGS 250
>XP_006722336
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RKLVALC 7
           RK+VA C
Sbjct: 271 RKVVAFC 277
>XP_006722335
          Length = 361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RKLVALC 7
           RK+VA C
Sbjct: 286 RKVVAFC 292
>XP_005256248
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           RKL A+C A
Sbjct: 522 RKLGAICRA 530
>XP_005266498
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  RKLVALCG 8
          +KL  LCG
Sbjct: 66 KKLEGLCG 73
>XP_006719237
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3    LVALCG 8
            L+A+CG
Sbjct: 1059 LIAICG 1064
>NP_113678
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RKLVALCGA 9
           RKL A+C A
Sbjct: 566 RKLGAICRA 574
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.143    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 601,269
Number of extensions: 683
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package