Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443161                                                              17    3301
XP_006710380                                                           17    3301
XP_005245788                                                           17    3301
XP_006710379                                                           17    3301
XP_006710378                                                           17    3301
NP_001264282                                                           17    4312
NP_115766                                                              16    5631
NP_000042                                                              16    7355
NP_065935                                                              16    7355
NP_055654                                                              16    7355
NP_115558                                                              16    7355
NP_003794                                                              16    7355
NP_062830                                                              16    7355
XP_006723903                                                           16    7355
XP_006723902                                                           16    7355
XP_006718908                                                           16    7355
XP_005271621                                                           16    7355
XP_006718907                                                           16    7355
XP_006718906                                                           16    7355
XP_005271619                                                           16    7355
XP_005271618                                                           16    7355
NP_002871                                                              15    9605
NP_620059                                                              15    9605
NP_001186329                                                           15    9605
NP_001186327                                                           15    9605
NP_001186326                                                           15    9605
NP_001186328                                                           15    9605
NP_001032519                                                           15    9605
NP_036356                                                              15    9605
NP_001182226                                                           15    9605
NP_001182225                                                           15    9605
NP_008905                                                              15    9605
NP_005489                                                              15    9605
NP_001265108                                                           15    9605
NP_001265106                                                           15    9605
NP_001265105                                                           15    9605
NP_001265103                                                           15    9605
NP_001265102                                                           15    9605
NP_001265100                                                           15    9605
NP_001265099                                                           15    9605
NP_006707                                                              15    9605
NP_001265104                                                           15    9605
NP_001265107                                                           15    9605
XP_005259758                                                           15    9605
XP_005267409                                                           15    9605
XP_006720108                                                           15    9605
XP_006715906                                                           15    9605
XP_005250178                                                           15    9605
XP_005250177                                                           15    9605
XP_006714291                                                           15    9605
XP_006714290                                                           15    9605
XP_006714213                                                           15    9605
XP_006714212                                                           15    9605
XP_005265715                                                           15    9605
XP_005265714                                                           15    9605
XP_006714211                                                           15    9605
XP_005265713                                                           15    9605
XP_005265417                                                           15    9605
XP_005265416                                                           15    9605
XP_005265415                                                           15    9605
XP_005265414                                                           15    9605
XP_005265412                                                           15    9605
NP_008885                                                              15    9605
>NP_443161
          Length = 1412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RITQQKNQI 9
            +ITQ KNQ+
Sbjct: 1293 KITQLKNQL 1301

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ+KN++
Sbjct: 730 ITQEKNRV 737
>XP_006710380
          Length = 1398

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RITQQKNQI 9
            +ITQ KNQ+
Sbjct: 1279 KITQLKNQL 1287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ+KN++
Sbjct: 752 ITQEKNRV 759
>XP_005245788
          Length = 1434

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RITQQKNQI 9
            +ITQ KNQ+
Sbjct: 1315 KITQLKNQL 1323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ+KN++
Sbjct: 752 ITQEKNRV 759
>XP_006710379
          Length = 1452

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RITQQKNQI 9
            +ITQ KNQ+
Sbjct: 1315 KITQLKNQL 1323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ+KN++
Sbjct: 752 ITQEKNRV 759
>XP_006710378
          Length = 1478

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RITQQKNQI 9
            +ITQ KNQ+
Sbjct: 1314 KITQLKNQL 1322

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ+KN++
Sbjct: 752 ITQEKNRV 759
>NP_001264282
          Length = 374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RITQQKNQI 9
          RITQ  NQ+
Sbjct: 27 RITQTNNQL 35
>NP_115766
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RITQQKNQ 8
          RITQ+K Q
Sbjct: 32 RITQRKKQ 39
>NP_000042
          Length = 3056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RITQQK 6
            RITQQK
Sbjct: 1575 RITQQK 1580
>NP_065935
          Length = 1983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITQQKNQI 9
           ITQ+KN +
Sbjct: 929 ITQEKNDL 936
>NP_055654
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RITQQKN 7
           RITQ KN
Sbjct: 297 RITQYKN 303
>NP_115558
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RITQQKNQ 8
           +ITQ+KN+
Sbjct: 247 QITQRKNE 254
>NP_003794
          Length = 1685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RITQQKNQI 9
           R+T  KNQ+
Sbjct: 307 RVTWYKNQV 315
>NP_062830
          Length = 1589

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RITQQKNQI 9
           R+T  KNQ+
Sbjct: 307 RVTWYKNQV 315
>XP_006723903
          Length = 1989

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITQQKNQI 9
           ITQ+KN +
Sbjct: 929 ITQEKNDL 936
>XP_006723902
          Length = 1787

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITQQKNQI 9
           ITQ+KN +
Sbjct: 727 ITQEKNDL 734
>XP_006718908
          Length = 1708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RITQQK 6
           RITQQK
Sbjct: 227 RITQQK 232
>XP_005271621
          Length = 2708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RITQQK 6
            RITQQK
Sbjct: 1227 RITQQK 1232
>XP_006718907
          Length = 3050

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RITQQK 6
            RITQQK
Sbjct: 1569 RITQQK 1574
>XP_006718906
          Length = 3056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RITQQK 6
            RITQQK
Sbjct: 1575 RITQQK 1580
>XP_005271619
          Length = 3056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RITQQK 6
            RITQQK
Sbjct: 1575 RITQQK 1580
>XP_005271618
          Length = 3056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RITQQK 6
            RITQQK
Sbjct: 1575 RITQQK 1580
>NP_002871
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN+I
Sbjct: 324 TQEKNKI 330
>NP_620059
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITQQKNQ 8
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>NP_001186329
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 894 RITIQENEV 902
>NP_001186327
          Length = 1242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 922 RITIQENEV 930
>NP_001186326
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 966 RITIQENEV 974
>NP_001186328
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 869 RITIQENEV 877
>NP_001032519
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 482 LTRQRNQL 489
>NP_036356
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 938 RITIQENEV 946
>NP_001182226
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITQQKNQ 8
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>NP_001182225
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITQQKNQ 8
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>NP_008905
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 186 TQEKNEV 192
>NP_005489
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITQQKNQI 9
           ITQQ N++
Sbjct: 135 ITQQSNKL 142
>NP_001265108
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  TQQKNQI 9
          TQ+KN++
Sbjct: 75 TQEKNEV 81
>NP_001265106
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 208 TQEKNEV 214
>NP_001265105
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 144 TQEKNEV 150
>NP_001265103
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  TQQKNQI 9
          TQ+KN++
Sbjct: 75 TQEKNEV 81
>NP_001265102
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 205 TQEKNEV 211
>NP_001265100
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  TQQKNQI 9
          TQ+KN++
Sbjct: 75 TQEKNEV 81
>NP_001265099
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 193 TQEKNEV 199
>NP_006707
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ++N+I
Sbjct: 603 ITQEENRI 610
>NP_001265104
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 109 TQEKNEV 115
>NP_001265107
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  TQQKNQI 9
          TQ+KN++
Sbjct: 75 TQEKNEV 81
>XP_005259758
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ITQQKNQI 9
           ITQQ N++
Sbjct: 135 ITQQSNKL 142
>XP_005267409
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITQQKNQ 8
           ITQQ+N+
Sbjct: 343 ITQQQNE 349
>XP_006720108
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ITQQKNQ 8
           ITQQ+N+
Sbjct: 379 ITQQQNE 385
>XP_006715906
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ++N+I
Sbjct: 379 ITQEENRI 386
>XP_005250178
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ++N+I
Sbjct: 379 ITQEENRI 386
>XP_005250177
          Length = 673

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           ITQ++N+I
Sbjct: 602 ITQEENRI 609
>XP_006714291
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 907 RITIQENEV 915
>XP_006714290
          Length = 1269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RITQQKNQI 9
           RIT Q+N++
Sbjct: 949 RITIQENEV 957
>XP_006714213
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 500 LTRQRNQL 507
>XP_006714212
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 500 LTRQRNQL 507
>XP_005265715
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 418 LTRQRNQL 425
>XP_005265714
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 429 LTRQRNQL 436
>XP_006714211
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 500 LTRQRNQL 507
>XP_005265713
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ITQQKNQI 9
           +T+Q+NQ+
Sbjct: 500 LTRQRNQL 507
>XP_005265417
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN+I
Sbjct: 324 TQEKNKI 330
>XP_005265416
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN+I
Sbjct: 210 TQEKNKI 216
>XP_005265415
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN+I
Sbjct: 243 TQEKNKI 249
>XP_005265414
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN+I
Sbjct: 291 TQEKNKI 297
>XP_005265412
          Length = 648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN+I
Sbjct: 324 TQEKNKI 330
>NP_008885
          Length = 811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TQQKNQI 9
           TQ+KN++
Sbjct: 187 TQEKNEV 193
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.125    0.305 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 463,254
Number of extensions: 598
Number of successful extensions: 68
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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