Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     869
NP_001185763                                                           19     869
NP_055459                                                              19     869
XP_006726436                                                           19     869
XP_006711784                                                           19     869
XP_006711719                                                           19     869
XP_006711718                                                           19     869
XP_006711717                                                           19     869
XP_006711716                                                           19     869
XP_006711715                                                           19     869
XP_006711714                                                           19     869
XP_006711713                                                           19     869
XP_006711712                                                           19     869
XP_006711711                                                           19     869
XP_006711710                                                           19     869
XP_006711709                                                           19     869
XP_005277503                                                           19     869
XP_005273038                                                           19     869
XP_006711708                                                           19     869
XP_005277500                                                           19     869
XP_006711707                                                           19     869
XP_005277499                                                           19     869
XP_006711706                                                           19     869
XP_006711705                                                           19     869
XP_006710122                                                           19     869
XP_006726410                                                           17    2528
XP_006711164                                                           17    2528
XP_005276114                                                           17    2528
NP_001095271                                                           17    4312
NP_001095270                                                           17    4312
XP_005272064                                                           17    4312
NP_001609                                                              16    5631
NP_006098                                                              16    5631
NP_057508                                                              16    5631
XP_005257512                                                           16    5631
XP_006722006                                                           16    5631
XP_005257511                                                           16    5631
XP_005257509                                                           16    5631
XP_005257508                                                           16    5631
XP_005257507                                                           16    5631
XP_005257506                                                           16    5631
XP_005257505                                                           16    5631
XP_005265253                                                           16    5631
NP_886552                                                              16    5631
NP_055461                                                              16    7355
NP_001159907                                                           16    7355
NP_001159908                                                           16    7355
NP_001159906                                                           16    7355
NP_002206                                                              16    7355
NP_443109                                                              16    7355
NP_001001653                                                           16    7355
NP_963836                                                              16    7355
XP_005258236                                                           16    7355
XP_006722431                                                           16    7355
XP_005258235                                                           16    7355
XP_005258234                                                           16    7355
NP_001490                                                              15    9605
NP_001003722                                                           15    9605
NP_851607                                                              15    9605
NP_065878                                                              15    9605
NP_065156                                                              15    9605
XP_005259257                                                           15    9605
XP_006717123                                                           15    9605
XP_005251982                                                           15    9605
XP_006717122                                                           15    9605
XP_006717121                                                           15    9605
XP_005263212                                                           15    9605
XP_005263211                                                           15    9605
XP_006711529                                                           15    9605
XP_006711528                                                           15    9605
NP_003361                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2177 RTKVSKQER 2185
>NP_001185763
          Length = 2362

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2283 RTKVSKQER 2291
>NP_055459
          Length = 2346

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2283 RTKVSKQER 2291
>XP_006726436
          Length = 178

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RIKVSKQER 9
          R KVSKQER
Sbjct: 61 RTKVSKQER 69
>XP_006711784
          Length = 178

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RIKVSKQER 9
          R KVSKQER
Sbjct: 61 RTKVSKQER 69
>XP_006711719
          Length = 2302

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2239 RTKVSKQER 2247
>XP_006711718
          Length = 1436

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 1290 RTKVSKQER 1298
>XP_006711717
          Length = 2385

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2239 RTKVSKQER 2247
>XP_006711716
          Length = 2411

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2348 RTKVSKQER 2356
>XP_006711715
          Length = 2428

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2282 RTKVSKQER 2290
>XP_006711714
          Length = 2429

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2283 RTKVSKQER 2291
>XP_006711713
          Length = 2432

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2286 RTKVSKQER 2294
>XP_006711712
          Length = 2473

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2327 RTKVSKQER 2335
>XP_006711711
          Length = 2482

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2336 RTKVSKQER 2344
>XP_006711710
          Length = 2494

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2348 RTKVSKQER 2356
>XP_006711709
          Length = 2495

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2349 RTKVSKQER 2357
>XP_005277503
          Length = 2498

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2446 RTKVSKQER 2454
>XP_005273038
          Length = 2509

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2446 RTKVSKQER 2454
>XP_006711708
          Length = 2512

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2366 RTKVSKQER 2374
>XP_005277500
          Length = 2525

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2446 RTKVSKQER 2454
>XP_006711707
          Length = 2553

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2407 RTKVSKQER 2415
>XP_005277499
          Length = 2561

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2446 RTKVSKQER 2454
>XP_006711706
          Length = 2591

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2445 RTKVSKQER 2453
>XP_006711705
          Length = 2592

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQER
Sbjct: 2446 RTKVSKQER 2454
>XP_006710122
          Length = 126

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RIKVSKQER 9
          R KVSKQER
Sbjct: 61 RTKVSKQER 69
>XP_006726410
          Length = 2087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQE+
Sbjct: 2024 RTKVSKQEQ 2032
>XP_006711164
          Length = 2087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    RIKVSKQER 9
            R KVSKQE+
Sbjct: 2024 RTKVSKQEQ 2032
>XP_005276114
          Length = 134

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RIKVSKQER 9
          R KVSKQE+
Sbjct: 31 RTKVSKQEQ 39
>NP_001095271
          Length = 791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IKVSKQER 9
           IKV+K+ER
Sbjct: 601 IKVTKEER 608
>NP_001095270
          Length = 887

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IKVSKQER 9
           IKV+K+ER
Sbjct: 697 IKVTKEER 704
>XP_005272064
          Length = 909

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IKVSKQER 9
           IKV+K+ER
Sbjct: 719 IKVTKEER 726
>NP_001609
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           ++KV KQ+R
Sbjct: 347 KLKVKKQDR 355
>NP_006098
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>NP_057508
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005257512
          Length = 387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_006722006
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 170 RLKKEKQER 178
>XP_005257511
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005257509
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005257508
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005257507
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005257506
          Length = 472

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005257505
          Length = 489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIKVSKQER 9
           R+K  KQER
Sbjct: 246 RLKKEKQER 254
>XP_005265253
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   RIKVSKQER 9
           R+K++K+E+
Sbjct: 312 RLKIAKEEK 320
>NP_886552
          Length = 434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   RIKVSKQER 9
           R+K++K+E+
Sbjct: 312 RLKIAKEEK 320
>NP_055461
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           KVSK+ER
Sbjct: 274 KVSKRER 280
>NP_001159907
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+KV ++ER
Sbjct: 290 RMKVDREER 298
>NP_001159908
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+KV ++ER
Sbjct: 290 RMKVDREER 298
>NP_001159906
          Length = 769

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+KV ++ER
Sbjct: 436 RMKVDREER 444
>NP_002206
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+KV ++ER
Sbjct: 578 RMKVDREER 586
>NP_443109
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           K+SK+ER
Sbjct: 153 KISKEER 159
>NP_001001653
          Length = 179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  KVSKQER 9
          K+SK+ER
Sbjct: 64 KISKEER 70
>NP_963836
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           K+SK+ER
Sbjct: 153 KISKEER 159
>XP_005258236
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           KVSK+ER
Sbjct: 274 KVSKRER 280
>XP_006722431
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           KVSK+ER
Sbjct: 274 KVSKRER 280
>XP_005258235
          Length = 896

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           KVSK+ER
Sbjct: 274 KVSKRER 280
>XP_005258234
          Length = 933

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KVSKQER 9
           KVSK+ER
Sbjct: 311 KVSKRER 317
>NP_001490
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+K ++QER
Sbjct: 227 RVKQAEQER 235
>NP_001003722
          Length = 698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+K ++QER
Sbjct: 227 RVKQAEQER 235
>NP_851607
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KVSKQER 9
           KVS QER
Sbjct: 639 KVSSQER 645
>NP_065878
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   RIKVSKQE 8
           ++K+ KQE
Sbjct: 278 KVKIKKQE 285
>NP_065156
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KVSKQER 9
           KVS QER
Sbjct: 585 KVSSQER 591
>XP_005259257
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KVSKQE 8
           KVSKQE
Sbjct: 237 KVSKQE 242
>XP_006717123
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+K ++QER
Sbjct: 230 RVKQAEQER 238
>XP_005251982
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+K ++QER
Sbjct: 227 RVKQAEQER 235
>XP_006717122
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+K ++QER
Sbjct: 230 RVKQAEQER 238
>XP_006717121
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RIKVSKQER 9
           R+K ++QER
Sbjct: 230 RVKQAEQER 238
>XP_005263212
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   RIKVSKQE 8
           ++K+ KQE
Sbjct: 278 KVKIKKQE 285
>XP_005263211
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   RIKVSKQE 8
           ++K+ KQE
Sbjct: 278 KVKIKKQE 285
>XP_006711529
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KVSKQER 9
           KVS QER
Sbjct: 443 KVSSQER 449
>XP_006711528
          Length = 742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   KVSKQER 9
           KVS QER
Sbjct: 639 KVSSQER 645
>NP_003361
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KVSKQE 8
           KVSKQE
Sbjct: 237 KVSKQE 242
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.125    0.291 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 421,705
Number of extensions: 815
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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