Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     869
NP_005913                                                              19     869
XP_005267046                                                           19     869
XP_005267045                                                           19     869
NP_862820                                                              17    4312
NP_001184188                                                           17    4312
NP_036513                                                              17    4312
XP_005248763                                                           17    4312
XP_005248762                                                           17    4312
XP_005248761                                                           17    4312
NP_056121                                                              16    5631
NP_004810                                                              15    9605
XP_005259343                                                           15    9605
>NP_006715
          Length = 1558

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RIALVTNDR 9
           RIALV NDR
Sbjct: 558 RIALVKNDR 566
>NP_005913
          Length = 1608

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RIALVTNDR 9
           RIALV NDR
Sbjct: 558 RIALVKNDR 566
>XP_005267046
          Length = 1554

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RIALVTNDR 9
           RIALV NDR
Sbjct: 558 RIALVKNDR 566
>XP_005267045
          Length = 1604

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RIALVTNDR 9
           RIALV NDR
Sbjct: 558 RIALVKNDR 566
>NP_862820
          Length = 712

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RIALVTNDR 9
           ++AL+TN+R
Sbjct: 384 QVALLTNER 392
>NP_001184188
          Length = 568

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RIALVTNDR 9
           ++AL+TN+R
Sbjct: 241 QVALLTNER 249
>NP_036513
          Length = 711

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RIALVTNDR 9
           ++AL+TN+R
Sbjct: 384 QVALLTNER 392
>XP_005248763
          Length = 659

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RIALVTNDR 9
           ++AL+TN+R
Sbjct: 331 QVALLTNER 339
>XP_005248762
          Length = 659

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RIALVTNDR 9
           ++AL+TN+R
Sbjct: 331 QVALLTNER 339
>XP_005248761
          Length = 684

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RIALVTNDR 9
           ++AL+TN+R
Sbjct: 384 QVALLTNER 392
>NP_056121
          Length = 2620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IALVTNDR 9
          +AL+TN+R
Sbjct: 38 VALLTNER 45
>NP_004810
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  ALVTND 8
          AL+TND
Sbjct: 44 ALITND 49
>XP_005259343
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  ALVTND 8
          AL+TND
Sbjct: 44 ALITND 49
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.139    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 407,225
Number of extensions: 491
Number of successful extensions: 13
Number of sequences better than 10000.0: 13
Number of HSP's gapped: 13
Number of HSP's successfully gapped: 13
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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