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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001099129                                                           18    1482
XP_005270510                                                           18    1482
XP_005270509                                                           18    1482
XP_005270508                                                           18    1482
NP_055068                                                              17    3301
NP_001156750                                                           17    3301
NP_001156751                                                           17    3301
NP_004629                                                              16    7355
NP_542417                                                              16    7355
NP_005052                                                              16    7355
XP_006726175                                                           16    7355
XP_006726174                                                           16    7355
XP_006726087                                                           16    7355
XP_006726086                                                           16    7355
XP_006725985                                                           16    7355
XP_006725897                                                           16    7355
XP_006725896                                                           16    7355
XP_006725787                                                           16    7355
XP_006725786                                                           16    7355
XP_006725571                                                           16    7355
XP_006725570                                                           16    7355
XP_006715254                                                           16    7355
XP_005247017                                                           16    7355
XP_006710416                                                           16    7355
XP_006710415                                                           16    7355
XP_005270511                                                           16    7355
NP_001010860                                                           16    7355
NP_005783                                                              15    9605
XP_005258913                                                           15    9605

>NP_001099129
          Length = 624

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   GMKSETSR 9
           GMKS+TSR
Sbjct: 320 GMKSKTSR 327



>XP_005270510
          Length = 335

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   GMKSETSR 9
           GMKS+TSR
Sbjct: 320 GMKSKTSR 327



>XP_005270509
          Length = 349

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   GMKSETSR 9
           GMKS+TSR
Sbjct: 320 GMKSKTSR 327



>XP_005270508
          Length = 430

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   GMKSETSR 9
           GMKS+TSR
Sbjct: 320 GMKSKTSR 327



>NP_055068
          Length = 2725

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RGMKSETS 8
           RGMKSE S
Sbjct: 126 RGMKSEHS 133



>NP_001156750
          Length = 2732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RGMKSETS 8
           RGMKSE S
Sbjct: 126 RGMKSEHS 133



>NP_001156751
          Length = 2731

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RGMKSETS 8
           RGMKSE S
Sbjct: 126 RGMKSEHS 133



>NP_004629
          Length = 2157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>NP_542417
          Length = 2157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>NP_005052
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RGMKSETSR 9
           RG+K  TSR
Sbjct: 226 RGVKGVTSR 234



>XP_006726175
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>XP_006726174
          Length = 2156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 818 KGMRSET 824



>XP_006726087
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>XP_006726086
          Length = 2156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 818 KGMRSET 824



>XP_006725985
          Length = 2156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 818 KGMRSET 824



>XP_006725897
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>XP_006725896
          Length = 2156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 818 KGMRSET 824



>XP_006725787
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>XP_006725786
          Length = 2156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 818 KGMRSET 824



>XP_006725571
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>XP_006725570
          Length = 2156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 818 KGMRSET 824



>XP_006715254
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGMKSET 7
           +GM+SET
Sbjct: 819 KGMRSET 825



>XP_005247017
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RGMKSETSR 9
           R  KSETS+
Sbjct: 294 RSSKSETSK 302



>XP_006710416
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3 MKSETSR 9
         MKS+TSR
Sbjct: 1 MKSKTSR 7



>XP_006710415
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3 MKSETSR 9
         MKS+TSR
Sbjct: 1 MKSKTSR 7



>XP_005270511
          Length = 304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3 MKSETSR 9
         MKS+TSR
Sbjct: 1 MKSKTSR 7



>NP_001010860
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MKSETSR 9
           +KSETSR
Sbjct: 107 VKSETSR 113



>NP_005783
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RGMKSETSR 9
          RG+ SET +
Sbjct: 21 RGLDSETKK 29



>XP_005258913
          Length = 197

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RGMKSETSR 9
          RG+ SET R
Sbjct: 6  RGLGSETVR 14



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.302    0.112    0.275 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,755
Number of extensions: 479
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)