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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
NP_001269644                                                           17    4312
NP_078789                                                              17    4312
NP_775820                                                              17    4312
NP_872293                                                              17    4312
XP_005251817                                                           17    4312
XP_005251816                                                           17    4312
XP_006717052                                                           17    4312
XP_005265541                                                           17    4312
XP_006713398                                                           17    4312
XP_006713397                                                           17    4312
XP_006713396                                                           17    4312
NP_258443                                                              16    5631
NP_005504                                                              16    5631
XP_006721637                                                           16    7355
XP_005256849                                                           16    7355
NP_055334                                                              16    7355
NP_653297                                                              15    9605
NP_775734                                                              15    9605
NP_001104595                                                           15    9605
NP_001124198                                                           15    9605
XP_006724643                                                           15    9605
XP_006724642                                                           15    9605
XP_006714048                                                           15    9605
XP_005248267                                                           15    9605
XP_006711223                                                           15    9605
XP_006711222                                                           15    9605
XP_006711221                                                           15    9605
XP_006711220                                                           15    9605

>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           REST EGTL
Sbjct: 554 RESTTEGTL 562



>NP_001269644
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RE++ EGTL
Sbjct: 177 REASCEGTL 185



>NP_078789
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RES I+G+L
Sbjct: 652 RESAIQGSL 660



>NP_775820
          Length = 374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RESTIEGTL 9
          REST++G +
Sbjct: 46 RESTVDGNV 54



>NP_872293
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RE++ EGTL
Sbjct: 391 REASCEGTL 399



>XP_005251817
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RE++ EGTL
Sbjct: 308 REASCEGTL 316



>XP_005251816
          Length = 613

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RE++ EGTL
Sbjct: 352 REASCEGTL 360



>XP_006717052
          Length = 616

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RE++ EGTL
Sbjct: 355 REASCEGTL 363



>XP_005265541
          Length = 1080

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RES I+G+L
Sbjct: 652 RESAIQGSL 660



>XP_006713398
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RES I+G+L
Sbjct: 652 RESAIQGSL 660



>XP_006713397
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RES I+G+L
Sbjct: 652 RESAIQGSL 660



>XP_006713396
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RESTIEGTL 9
           RES I+G+L
Sbjct: 652 RESAIQGSL 660



>NP_258443
          Length = 1035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   STIEGTL 9
           STI+GTL
Sbjct: 567 STIQGTL 573



>NP_005504
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RESTIEG 7
           REST++G
Sbjct: 282 RESTVQG 288



>XP_006721637
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ESTIEGTL 9
           E+T EGTL
Sbjct: 229 EATSEGTL 236



>XP_005256849
          Length = 435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ESTIEGTL 9
           E+T EGTL
Sbjct: 248 EATSEGTL 255



>NP_055334
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ESTIEGTL 9
           E+T EGTL
Sbjct: 257 EATSEGTL 264



>NP_653297
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RESTIEGTL 9
           RES  +GTL
Sbjct: 906 RESAKQGTL 914



>NP_775734
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RESTIEG 7
           RES IEG
Sbjct: 467 RESPIEG 473



>NP_001104595
          Length = 1488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ESTIEGTL 9
            +STIEG++
Sbjct: 1163 DSTIEGSV 1170



>NP_001124198
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RESTIEG 7
           RES IEG
Sbjct: 467 RESPIEG 473



>XP_006724643
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ESTIEGTL 9
           +STIEG++
Sbjct: 958 DSTIEGSV 965



>XP_006724642
          Length = 1520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ESTIEGTL 9
            +STIEG++
Sbjct: 1195 DSTIEGSV 1202



>XP_006714048
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RESTIEG 7
           RES IEG
Sbjct: 478 RESPIEG 484



>XP_005248267
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RESTIEG 7
           RES IEG
Sbjct: 478 RESPIEG 484



>XP_006711223
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RESTIEGTL 9
           RES  +GTL
Sbjct: 807 RESAKQGTL 815



>XP_006711222
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RESTIEGTL 9
           RES  +GTL
Sbjct: 864 RESAKQGTL 872



>XP_006711221
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RESTIEGTL 9
           RES  +GTL
Sbjct: 870 RESAKQGTL 878



>XP_006711220
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RESTIEGTL 9
           RES  +GTL
Sbjct: 906 RESAKQGTL 914



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.124    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 486,828
Number of extensions: 573
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)