Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056247                                                              16    5631
NP_695001                                                              16    5631
NP_001123203                                                           16    5631
NP_001098714                                                           16    5631
NP_542138                                                              16    5631
XP_005260723                                                           16    5631
XP_006723606                                                           16    5631
XP_006722401                                                           16    5631
XP_006722400                                                           16    5631
XP_006722399                                                           16    5631
XP_006722398                                                           16    5631
NP_001123199                                                           16    5631
NP_001123200                                                           16    5631
NP_001123201                                                           16    5631
NP_002836                                                              16    5631
NP_036346                                                              16    7355
NP_055625                                                              16    7355
NP_036395                                                              16    7355
NP_036392                                                              16    7355
NP_001271342                                                           16    7355
NP_001271345                                                           16    7355
XP_006724288                                                           16    7355
XP_006711734                                                           16    7355
XP_006711733                                                           16    7355
XP_006711732                                                           16    7355
XP_006711731                                                           16    7355
XP_006711730                                                           16    7355
XP_006711729                                                           16    7355
XP_005245695                                                           16    7355
NP_005393                                                              15    9605
NP_006333                                                              15    9605
NP_001171826                                                           15    9605
NP_001135919                                                           15    9605
NP_055922                                                              15    9605
NP_001171825                                                           15    9605
NP_036201                                                              15    9605
NP_001129502                                                           15    9605
NP_001092285                                                           15    9605
NP_001248773                                                           15    9605
NP_055611                                                              15    9605
NP_001171827                                                           15    9605
NP_112557                                                              15    9605
NP_003709                                                              15    9605
XP_006724648                                                           15    9605
XP_005262057                                                           15    9605
XP_005262055                                                           15    9605
XP_005262056                                                           15    9605
XP_005262054                                                           15    9605
XP_005262053                                                           15    9605
XP_005269304                                                           15    9605
XP_006719779                                                           15    9605
XP_005269303                                                           15    9605
XP_006719778                                                           15    9605
XP_005269302                                                           15    9605
XP_005269301                                                           15    9605
XP_005269300                                                           15    9605
XP_006715826                                                           15    9605
XP_006715825                                                           15    9605
XP_005247987                                                           15    9605
XP_006713918                                                           15    9605
XP_005247986                                                           15    9605
>NP_056247
          Length = 1191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RELRSRKSL 9
            RE+RSR S+
Sbjct: 1073 REVRSRASI 1081
>NP_695001
          Length = 363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RELRSRKS 8
           RELRSR++
Sbjct: 113 RELRSREN 120
>NP_001123203
          Length = 1110

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RELRSRKSL 9
            RE+RSR S+
Sbjct: 992  REVRSRASI 1000
>NP_001098714
          Length = 1465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RELRSRK 7
            RELRSR+
Sbjct: 1141 RELRSRR 1147
>NP_542138
          Length = 362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RELRSRKS 8
           RELRSR++
Sbjct: 112 RELRSREN 119
>XP_005260723
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  RELRSRKS 8
          RELRSR++
Sbjct: 78 RELRSREN 85
>XP_006723606
          Length = 310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  RELRSRKS 8
          RELRSR++
Sbjct: 60 RELRSREN 67
>XP_006722401
          Length = 1432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RELRSRK 7
            RELRSR+
Sbjct: 1108 RELRSRR 1114
>XP_006722400
          Length = 1469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RELRSRK 7
            RELRSR+
Sbjct: 1145 RELRSRR 1151
>XP_006722399
          Length = 1477

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RELRSRK 7
            RELRSR+
Sbjct: 1153 RELRSRR 1159
>XP_006722398
          Length = 1494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RELRSRK 7
            RELRSR+
Sbjct: 1170 RELRSRR 1176
>NP_001123199
          Length = 1191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RELRSRKSL 9
            RE+RSR S+
Sbjct: 1073 REVRSRASI 1081
>NP_001123200
          Length = 1191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RELRSRKSL 9
            RE+RSR S+
Sbjct: 1073 REVRSRASI 1081
>NP_001123201
          Length = 1191

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RELRSRKSL 9
            RE+RSR S+
Sbjct: 1073 REVRSRASI 1081
>NP_002836
          Length = 1452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RELRSRK 7
            RELRSR+
Sbjct: 1128 RELRSRR 1134
>NP_036346
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           +EL S+KSL
Sbjct: 95  KELTSKKSL 103
>NP_055625
          Length = 3117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2060 ELRKRKSV 2067
>NP_036395
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RELRSRK 7
           RELRSR+
Sbjct: 394 RELRSRQ 400
>NP_036392
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           +EL S+KSL
Sbjct: 365 KELASKKSL 373
>NP_001271342
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           +EL S+KSL
Sbjct: 338 KELASKKSL 346
>NP_001271345
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           +EL S+KSL
Sbjct: 283 KELASKKSL 291
>XP_006724288
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RELRSRK 7
           RELRSR+
Sbjct: 297 RELRSRQ 303
>XP_006711734
          Length = 3136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2079 ELRKRKSV 2086
>XP_006711733
          Length = 3137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2080 ELRKRKSV 2087
>XP_006711732
          Length = 3154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2097 ELRKRKSV 2104
>XP_006711731
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2100 ELRKRKSV 2107
>XP_006711730
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2100 ELRKRKSV 2107
>XP_006711729
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2101 ELRKRKSV 2108
>XP_005245695
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ELRSRKSL 9
            ELR RKS+
Sbjct: 2101 ELRKRKSV 2108
>NP_005393
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RELRSRK 7
           RE+R+RK
Sbjct: 173 REIRARK 179
>NP_006333
          Length = 838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 656 RELRSR 661
>NP_001171826
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RELRSR 6
          RELRSR
Sbjct: 89 RELRSR 94
>NP_001135919
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RELRSRKS 8
          R+LRSR++
Sbjct: 3  RQLRSRRA 10
>NP_055922
          Length = 1024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RELRSR 6
          RELRSR
Sbjct: 89 RELRSR 94
>NP_001171825
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 125 RELRSR 130
>NP_036201
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  RELRSRKS 8
          R+LRSR++
Sbjct: 3  RQLRSRRA 10
>NP_001129502
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>NP_001092285
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>NP_001248773
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 296 RKSRARKSL 304
>NP_055611
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 296 RKSRARKSL 304
>NP_001171827
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RELRSR 6
          RELRSR
Sbjct: 89 RELRSR 94
>NP_112557
          Length = 1452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RELRSRKS 8
           + LRSRKS
Sbjct: 333 QSLRSRKS 340
>NP_003709
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RELRSRKS 8
           + LRSRKS
Sbjct: 333 QSLRSRKS 340
>XP_006724648
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 125 RELRSR 130
>XP_005262057
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 125 RELRSR 130
>XP_005262055
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RELRSR 6
          RELRSR
Sbjct: 89 RELRSR 94
>XP_005262056
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RELRSR 6
          RELRSR
Sbjct: 89 RELRSR 94
>XP_005262054
          Length = 1049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  RELRSR 6
          RELRSR
Sbjct: 89 RELRSR 94
>XP_005262053
          Length = 1085

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 125 RELRSR 130
>XP_005269304
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 296 RKSRARKSL 304
>XP_006719779
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>XP_005269303
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>XP_006719778
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>XP_005269302
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>XP_005269301
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>XP_005269300
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RELRSRKSL 9
           R+ R+RKSL
Sbjct: 434 RKSRARKSL 442
>XP_006715826
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RELRSRK 7
           RE+R+RK
Sbjct: 173 REIRARK 179
>XP_006715825
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RELRSRK 7
           RE+R+RK
Sbjct: 173 REIRARK 179
>XP_005247987
          Length = 482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 300 RELRSR 305
>XP_006713918
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 648 RELRSR 653
>XP_005247986
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RELRSR 6
           RELRSR
Sbjct: 660 RELRSR 665
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.129    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 449,284
Number of extensions: 740
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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