Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              19     665
NP_002230                                                              17    4312
NP_056475                                                              16    5631
NP_057336                                                              16    7355
NP_001155130                                                           16    7355
NP_001155131                                                           16    7355
NP_001155128                                                           16    7355
NP_001155129                                                           16    7355
NP_001123644                                                           16    7355
NP_001123645                                                           16    7355
NP_005366                                                              16    7355
NP_003348                                                              16    7355
NP_149037                                                              16    7355
NP_001171700                                                           16    7355
XP_006715558                                                           16    7355
XP_006712120                                                           16    7355
XP_005264512                                                           16    7355
XP_005264511                                                           16    7355
XP_006712119                                                           16    7355
XP_005264510                                                           16    7355
XP_006712118                                                           16    7355
XP_005264509                                                           16    7355
XP_005264508                                                           16    7355
XP_006712117                                                           16    7355
XP_005264507                                                           16    7355
XP_005264506                                                           16    7355
NP_116193                                                              16    7355
NP_000651                                                              15    9605
NP_006039                                                              15    9605
NP_001099032                                                           15    9605
NP_003061                                                              15    9605
NP_001276325                                                           15    9605
NP_620614                                                              15    9605
NP_055733                                                              15    9605
NP_000172                                                              15    9605
NP_000422                                                              15    9605
XP_006720498                                                           15    9605
XP_005253941                                                           15    9605
XP_005253940                                                           15    9605
XP_005250354                                                           15    9605
XP_005263479                                                           15    9605
NP_001107657                                                           15    9605
>NP_004295
          Length = 1620

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   REILLMSTP 9
           REILLM TP
Sbjct: 373 REILLMPTP 381
>NP_002230
          Length = 501

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EILLMSTP 9
           E+LLMS+P
Sbjct: 363 EMLLMSSP 370
>NP_056475
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  REILLMSTP 9
          REI+++ TP
Sbjct: 71 REIVIIDTP 79
>NP_057336
          Length = 4857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3180 EVLLQATP 3187
>NP_001155130
          Length = 745

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001155131
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001155128
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001155129
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001123644
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_001123645
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_005366
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>NP_003348
          Length = 91

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EILLMSTP 9
          E LLM TP
Sbjct: 32 ETLLMDTP 39
>NP_149037
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  EILLMSTP 9
          E+LL+ TP
Sbjct: 88 ELLLLQTP 95
>NP_001171700
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  EILLMSTP 9
          E+LL+ TP
Sbjct: 88 ELLLLQTP 95
>XP_006715558
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+LLMST
Sbjct: 299 ELLLMST 305
>XP_006712120
          Length = 4812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3135 EVLLQATP 3142
>XP_005264512
          Length = 4840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3163 EVLLQATP 3170
>XP_005264511
          Length = 4847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3207 EVLLQATP 3214
>XP_006712119
          Length = 4851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3174 EVLLQATP 3181
>XP_005264510
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3184 EVLLQATP 3191
>XP_006712118
          Length = 4864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3207 EVLLQATP 3214
>XP_005264509
          Length = 4870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3193 EVLLQATP 3200
>XP_005264508
          Length = 4875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3198 EVLLQATP 3205
>XP_006712117
          Length = 4878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3201 EVLLQATP 3208
>XP_005264507
          Length = 4880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3203 EVLLQATP 3210
>XP_005264506
          Length = 4884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    EILLMSTP 9
            E+LL +TP
Sbjct: 3207 EVLLQATP 3214
>NP_116193
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   REILLMSTP 9
           RE+ L+ TP
Sbjct: 243 REVWLLETP 251
>NP_000651
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILLMSTP 9
           +LLM+TP
Sbjct: 258 LLLMATP 264
>NP_006039
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+L+MST
Sbjct: 208 EVLMMST 214
>NP_001099032
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+L+MST
Sbjct: 208 EVLMMST 214
>NP_003061
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   REILLMSTP 9
           R ILL  TP
Sbjct: 875 RRILLTGTP 883
>NP_001276325
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   REILLMSTP 9
           R ILL  TP
Sbjct: 875 RRILLTGTP 883
>NP_620614
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   REILLMSTP 9
           R ILL  TP
Sbjct: 875 RRILLTGTP 883
>NP_055733
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   REILLMS 7
           REI+LMS
Sbjct: 336 REIVLMS 342
>NP_000172
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   REILLMSTP 9
           R +LL +TP
Sbjct: 216 RSVLLYTTP 224
>NP_000422
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  EILLMSTP 9
          E+LL+S P
Sbjct: 4  EVLLVSAP 11
>XP_006720498
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  REILLMS 7
          REI+LMS
Sbjct: 64 REIVLMS 70
>XP_005253941
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  EILLMSTP 9
          E+LL+S P
Sbjct: 4  EVLLVSAP 11
>XP_005253940
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  EILLMSTP 9
          E+LL+S P
Sbjct: 4  EVLLVSAP 11
>XP_005250354
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   REILLMSTP 9
           R +LL +TP
Sbjct: 216 RSVLLYTTP 224
>XP_005263479
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EILLMST 8
           E+L+MST
Sbjct: 208 EVLMMST 214
>NP_001107657
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  EILLMSTP 9
          E+LL+S P
Sbjct: 4  EVLLVSAP 11
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.137    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 478,617
Number of extensions: 711
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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