Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001273575                                                           17    2528
NP_001073900                                                           17    2528
NP_001273577                                                           17    2528
XP_006716668                                                           17    2528
XP_006716667                                                           17    2528
NP_004624                                                              17    4312
NP_003165                                                              17    4312
NP_068506                                                              17    4312
XP_006717559                                                           17    4312
XP_006717558                                                           17    4312
XP_006717557                                                           17    4312
XP_006717556                                                           17    4312
XP_005252630                                                           17    4312
XP_005252629                                                           17    4312
XP_005252628                                                           17    4312
XP_005252627                                                           17    4312
XP_005252626                                                           17    4312
XP_005252625                                                           17    4312
XP_005252624                                                           17    4312
XP_005252623                                                           17    4312
XP_005252622                                                           17    4312
XP_006717555                                                           17    4312
XP_005252621                                                           17    4312
XP_006712799                                                           17    4312
XP_006712798                                                           17    4312
XP_006712797                                                           17    4312
XP_006712796                                                           17    4312
NP_002495                                                              16    5631
NP_667344                                                              16    5631
XP_005257785                                                           16    5631
XP_005251531                                                           16    5631
XP_005251530                                                           16    5631
NP_115510                                                              16    5631
NP_776182                                                              16    7355
NP_056436                                                              16    7355
NP_001018048                                                           15    9605
NP_056001                                                              15    9605
NP_001018047                                                           15    9605
NP_150648                                                              15    9605
NP_001018098                                                           15    9605
NP_060154                                                              15    9605
NP_060550                                                              15    9605
NP_065872                                                              15    9605
NP_055455                                                              15    9605
NP_002194                                                              15    9605
XP_006712937                                                           15    9605
XP_006712936                                                           15    9605
XP_005247034                                                           15    9605
>NP_001273575
          Length = 808

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           R+ASSTF +
Sbjct: 421 RQASSTFSY 429
>NP_001073900
          Length = 798

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           R+ASSTF +
Sbjct: 370 RQASSTFSY 378
>NP_001273577
          Length = 717

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           R+ASSTF +
Sbjct: 370 RQASSTFSY 378
>XP_006716668
          Length = 656

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           R+ASSTF +
Sbjct: 228 RQASSTFSY 236
>XP_006716667
          Length = 768

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           R+ASSTF +
Sbjct: 421 RQASSTFSY 429
>NP_004624
          Length = 398

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           +EASSTF +
Sbjct: 342 KEASSTFSW 350
>NP_003165
          Length = 1788

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 225 ESSSTFSF 232
>NP_068506
          Length = 2214

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 225 ESSSTFSF 232
>XP_006717559
          Length = 1866

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_006717558
          Length = 1908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_006717557
          Length = 1940

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_006717556
          Length = 2024

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_005252630
          Length = 2256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 225 ESSSTFSF 232
>XP_005252629
          Length = 2256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 225 ESSSTFSF 232
>XP_005252628
          Length = 2256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 225 ESSSTFSF 232
>XP_005252627
          Length = 2256

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 225 ESSSTFSF 232
>XP_005252626
          Length = 2260

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_005252625
          Length = 2277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_005252624
          Length = 2292

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_005252623
          Length = 2302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_005252622
          Length = 2308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_006717555
          Length = 2328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 297 ESSSTFSF 304
>XP_005252621
          Length = 2334

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EASSTFQF 9
           E+SSTF F
Sbjct: 303 ESSSTFSF 310
>XP_006712799
          Length = 423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           +EASSTF +
Sbjct: 367 KEASSTFSW 375
>XP_006712798
          Length = 313

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           +EASSTF +
Sbjct: 257 KEASSTFSW 265
>XP_006712797
          Length = 398

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           +EASSTF +
Sbjct: 342 KEASSTFSW 350
>XP_006712796
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   REASSTFQF 9
           +EASSTF +
Sbjct: 346 KEASSTFSW 354
>NP_002495
          Length = 1120

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EASSTFQ 8
           EASST+Q
Sbjct: 903 EASSTYQ 909
>NP_667344
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EASSTFQ 8
           EASST+Q
Sbjct: 903 EASSTYQ 909
>XP_005257785
          Length = 1887

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSTFQF 9
           SSTFQF
Sbjct: 330 SSTFQF 335
>XP_005251531
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EASSTFQ 8
           EASST+Q
Sbjct: 904 EASSTYQ 910
>XP_005251530
          Length = 1121

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EASSTFQ 8
           EASST+Q
Sbjct: 904 EASSTYQ 910
>NP_115510
          Length = 1663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SSTFQF 9
           SSTFQF
Sbjct: 164 SSTFQF 169
>NP_776182
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   REASSTFQF 9
           +EAS TF F
Sbjct: 364 KEASITFPF 372
>NP_056436
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   REASSTFQ 8
           REASST Q
Sbjct: 124 REASSTQQ 131
>NP_001018048
          Length = 3069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3017 ASSTFQ 3022
>NP_056001
          Length = 3095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3017 ASSTFQ 3022
>NP_001018047
          Length = 3135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 2978 ASSTFQ 2983
>NP_150648
          Length = 3174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3017 ASSTFQ 3022
>NP_001018098
          Length = 3628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3574 ASSTFQ 3579
>NP_060154
          Length = 3710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3531 ASSTFQ 3536
>NP_060550
          Length = 3585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3531 ASSTFQ 3536
>NP_065872
          Length = 3753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 3574 ASSTFQ 3579
>NP_055455
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
>NP_002194
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 1085 ASSTFQ 1090
>XP_006712937
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
>XP_006712936
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
>XP_005247034
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    ASSTFQ 8
            ASSTFQ
Sbjct: 1183 ASSTFQ 1188
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.120    0.312 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,959
Number of extensions: 464
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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