Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              21     229
NP_001075109                                                           21     229
NP_001091681                                                           18    1135
NP_001091683                                                           18    1135
NP_001091682                                                           18    1135
NP_000852                                                              18    1135
NP_001269109                                                           18    1935
NP_006237                                                              18    1935
NP_001269111                                                           18    1935
NP_001269110                                                           18    1935
NP_001269108                                                           18    1935
NP_997300                                                              17    2528
NP_001269886                                                           17    2528
NP_036423                                                              17    3301
XP_006719768                                                           17    3301
NP_005049                                                              16    5631
NP_001006121                                                           16    5631
NP_689798                                                              16    5631
NP_001006118                                                           16    5631
XP_005262647                                                           16    5631
XP_005262646                                                           16    5631
XP_005262645                                                           16    5631
XP_005262644                                                           16    5631
XP_005262643                                                           16    5631
XP_005262642                                                           16    5631
XP_005262641                                                           16    5631
XP_005262640                                                           16    5631
XP_005262634                                                           16    5631
XP_005262633                                                           16    5631
XP_005262632                                                           16    5631
XP_005262631                                                           16    5631
XP_005262574                                                           16    5631
XP_005262573                                                           16    5631
XP_005262572                                                           16    5631
XP_005262571                                                           16    5631
XP_005262570                                                           16    5631
XP_005262569                                                           16    5631
XP_005262568                                                           16    5631
NP_001006117                                                           16    5631
NP_001006120                                                           16    5631
NP_997244                                                              16    7355
NP_110447                                                              16    7355
NP_000821                                                              16    7355
NP_783300                                                              16    7355
NP_037495                                                              16    7355
NP_001161707                                                           16    7355
XP_005261001                                                           16    7355
XP_005261000                                                           16    7355
XP_005260999                                                           16    7355
XP_006724054                                                           16    7355
XP_006715287                                                           16    7355
XP_006715286                                                           16    7355
NP_001261                                                              15    9605
XP_005271924                                                           15    9605
XP_005271923                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RDYVAVSRG 9
            RDYVAV+RG
Sbjct: 4075 RDYVAVARG 4083
>NP_001075109
          Length = 4097

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RDYVAVSRG 9
            RDYVAV+RG
Sbjct: 4044 RDYVAVARG 4052
>NP_001091681
          Length = 487

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   RDYVAVSR 8
           RDYVAV+R
Sbjct: 319 RDYVAVNR 326
>NP_001091683
          Length = 487

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   RDYVAVSR 8
           RDYVAV+R
Sbjct: 319 RDYVAVNR 326
>NP_001091682
          Length = 487

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   RDYVAVSR 8
           RDYVAV+R
Sbjct: 319 RDYVAVNR 326
>NP_000852
          Length = 487

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   RDYVAVSR 8
           RDYVAV+R
Sbjct: 319 RDYVAVNR 326
>NP_001269109
          Length = 462

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DYVAVSRG 9
           DY+ +SRG
Sbjct: 98  DYITISRG 105
>NP_006237
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DYVAVSRG 9
           DY+ +SRG
Sbjct: 98  DYITISRG 105
>NP_001269111
          Length = 391

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DYVAVSRG 9
          DY+ +SRG
Sbjct: 22 DYITISRG 29
>NP_001269110
          Length = 391

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DYVAVSRG 9
          DY+ +SRG
Sbjct: 22 DYITISRG 29
>NP_001269108
          Length = 467

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DYVAVSRG 9
           DY+ +SRG
Sbjct: 98  DYITISRG 105
>NP_997300
          Length = 320

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDYVAVSRG 9
           R+Y+A++RG
Sbjct: 154 RNYIAMNRG 162
>NP_001269886
          Length = 284

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDYVAVSRG 9
           R+Y+A++RG
Sbjct: 118 RNYIAMNRG 126
>NP_036423
          Length = 2120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RDYVAVSRG 9
           +DY AV+RG
Sbjct: 138 QDYEAVARG 146
>XP_006719768
          Length = 2120

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RDYVAVSRG 9
           +DY AV+RG
Sbjct: 138 QDYEAVARG 146
>NP_005049
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>NP_001006121
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>NP_689798
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>NP_001006118
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>XP_005262647
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262646
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262645
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262644
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262643
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262642
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>XP_005262641
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262640
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262634
          Length = 419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>XP_005262633
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262632
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262631
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262574
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262573
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>XP_005262572
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262571
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262570
          Length = 459

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>XP_005262569
          Length = 466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>XP_005262568
          Length = 503

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 236 RDYAPPSRG 244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 273 RDYAPPSRG 281
>NP_001006117
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>NP_001006120
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 229 RDYAPPSRG 237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RDYVAVSRG 9
           RDY   SRG
Sbjct: 266 RDYAPPSRG 274
>NP_997244
          Length = 3169

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    DYVAVSR 8
            DYV +SR
Sbjct: 2060 DYVGISR 2066
>NP_110447
          Length = 957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   DYVAVSR 8
           DY+A+S+
Sbjct: 196 DYIAISK 202
>NP_000821
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DYVAVSR 8
           DY A+SR
Sbjct: 153 DYAAISR 159
>NP_783300
          Length = 905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DYVAVSR 8
           DY A+SR
Sbjct: 153 DYAAISR 159
>NP_037495
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DYVAVSRG 9
           DYVAV  G
Sbjct: 211 DYVAVFNG 218
>NP_001161707
          Length = 2139

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    DYVAVSR 8
            DYV +SR
Sbjct: 2063 DYVGISR 2069
>XP_005261001
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DYVAVSR 8
           DY A+SR
Sbjct: 153 DYAAISR 159
>XP_005261000
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DYVAVSR 8
           DY A+SR
Sbjct: 153 DYAAISR 159
>XP_005260999
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DYVAVSR 8
           DY A+SR
Sbjct: 153 DYAAISR 159
>XP_006724054
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   DYVAVSR 8
           DY A+SR
Sbjct: 153 DYAAISR 159
>XP_006715287
          Length = 615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   DYVAVSR 8
           DY+A+S+
Sbjct: 196 DYIAISK 202
>XP_006715286
          Length = 945

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   DYVAVSR 8
           DY+A+S+
Sbjct: 196 DYIAISK 202
>NP_001261
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RDYVAVSRG 9
           R+Y A+S+G
Sbjct: 732 RNYKALSKG 740
>XP_005271924
          Length = 1710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RDYVAVSRG 9
           R+Y A+S+G
Sbjct: 732 RNYKALSKG 740
>XP_005271923
          Length = 1798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RDYVAVSRG 9
           R+Y A+S+G
Sbjct: 732 RNYKALSKG 740
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.138    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 450,589
Number of extensions: 733
Number of successful extensions: 80
Number of sequences better than 10000.0: 55
Number of HSP's gapped: 80
Number of HSP's successfully gapped: 80
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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