Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     390
NP_001185763                                                           20     390
NP_055459                                                              20     390
NP_001002811                                                           20     390
NP_001002812                                                           20     390
XP_006726410                                                           20     390
XP_006711719                                                           20     390
XP_006711717                                                           20     390
XP_006711716                                                           20     390
XP_006711715                                                           20     390
XP_006711714                                                           20     390
XP_006711713                                                           20     390
XP_006711712                                                           20     390
XP_006711711                                                           20     390
XP_006711710                                                           20     390
XP_006711709                                                           20     390
XP_005277503                                                           20     390
XP_005273038                                                           20     390
XP_006711708                                                           20     390
XP_005277500                                                           20     390
XP_006711707                                                           20     390
XP_005277499                                                           20     390
XP_006711706                                                           20     390
XP_006711705                                                           20     390
XP_006711164                                                           20     390
XP_003846806                                                           20     390
NP_001020330                                                           17    3301
NP_001020329                                                           17    3301
NP_004346                                                              17    3301
XP_006714874                                                           17    3301
NP_065387                                                              16    7355
NP_001230395                                                           15    9605
NP_821075                                                              15    9605
NP_443083                                                              15    9605
NP_821074                                                              15    9605
NP_001230405                                                           15    9605
NP_001230403                                                           15    9605
NP_001004342                                                           15    9605
XP_006719952                                                           15    9605
XP_006719951                                                           15    9605
XP_005266643                                                           15    9605
XP_005273195                                                           15    9605
XP_005273194                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 590 RDVLSSNEA 598
>NP_001185763
          Length = 2362

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 524 RDVLSSNEA 532
>NP_055459
          Length = 2346

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 524 RDVLSSNEA 532
>NP_001002811
          Length = 1132

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>NP_001002812
          Length = 969

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 524 RDVLSSNEA 532
>XP_006726410
          Length = 2087

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 599 RDVLSSNEA 607
>XP_006711719
          Length = 2302

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 590 RDVLSSNEA 598
>XP_006711717
          Length = 2385

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 590 RDVLSSNEA 598
>XP_006711716
          Length = 2411

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 590 RDVLSSNEA 598
>XP_006711715
          Length = 2428

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 524 RDVLSSNEA 532
>XP_006711714
          Length = 2429

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 524 RDVLSSNEA 532
>XP_006711713
          Length = 2432

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 527 RDVLSSNEA 535
>XP_006711712
          Length = 2473

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711711
          Length = 2482

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711710
          Length = 2494

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 590 RDVLSSNEA 598
>XP_006711709
          Length = 2495

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 590 RDVLSSNEA 598
>XP_005277503
          Length = 2498

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_005273038
          Length = 2509

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711708
          Length = 2512

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_005277500
          Length = 2525

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711707
          Length = 2553

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_005277499
          Length = 2561

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711706
          Length = 2591

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711705
          Length = 2592

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 687 RDVLSSNEA 695
>XP_006711164
          Length = 2087

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDVISSNEA 9
           RDV+SSNEA
Sbjct: 599 RDVLSSNEA 607
>XP_003846806
          Length = 136

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  RDVISSNEA 9
          RDV+SSNEA
Sbjct: 53 RDVLSSNEA 61
>NP_001020330
          Length = 296

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  RDVISSNE 8
          RD+IS+NE
Sbjct: 21 RDLISNNE 28
>NP_001020329
          Length = 160

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  RDVISSNE 8
          RD+IS+NE
Sbjct: 21 RDLISNNE 28
>NP_004346
          Length = 232

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  RDVISSNE 8
          RD+IS+NE
Sbjct: 21 RDLISNNE 28
>XP_006714874
          Length = 334

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RDVISSNE 8
           RD+IS+NE
Sbjct: 98  RDLISNNE 105
>NP_065387
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   RDVISSNE 8
           RDVISS E
Sbjct: 845 RDVISSVE 852
>NP_001230395
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 545 RDVTSLNES 553
>NP_821075
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 545 RDVTSLNES 553
>NP_443083
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 435 RDVTSLNES 443
>NP_821074
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 553 RDVTSLNES 561
>NP_001230405
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 518 RDVTSLNES 526
>NP_001230403
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 435 RDVTSLNES 443
>NP_001004342
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RDVISSNE 8
           RD+I SN+
Sbjct: 619 RDIILSND 626
>XP_006719952
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 435 RDVTSLNES 443
>XP_006719951
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 435 RDVTSLNES 443
>XP_005266643
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDVISSNEA 9
           RDV S NE+
Sbjct: 538 RDVTSLNES 546
>XP_005273195
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RDVISSNE 8
           RD+I SN+
Sbjct: 557 RDIILSND 564
>XP_005273194
          Length = 756

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RDVISSNE 8
           RD+I SN+
Sbjct: 619 RDIILSND 626
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.115    0.269 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,336
Number of extensions: 694
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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