Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006715629                                                           17    3301
NP_078970                                                              17    3301
NP_001243415                                                           16    5631
NP_001243417                                                           16    5631
NP_004478                                                              16    5631
NP_001243416                                                           16    5631
NP_055490                                                              16    5631
NP_001278086                                                           16    5631
NP_002461                                                              16    5631
NP_001181876                                                           16    5631
NP_937887                                                              16    5631
NP_937884                                                              16    5631
NP_004944                                                              16    5631
NP_001181875                                                           16    5631
NP_937885                                                              16    5631
NP_886553                                                              16    5631
NP_057520                                                              16    5631
NP_001261                                                              16    5631
XP_006721591                                                           16    5631
XP_005271924                                                           16    5631
XP_005271923                                                           16    5631
XP_006713654                                                           16    5631
XP_006713653                                                           16    5631
XP_005247430                                                           16    5631
XP_005247429                                                           16    5631
XP_006713652                                                           16    5631
XP_006713651                                                           16    5631
XP_006713650                                                           16    5631
XP_005247428                                                           16    5631
XP_006711123                                                           16    5631
XP_006711122                                                           16    5631
XP_006711121                                                           16    5631
XP_006711120                                                           16    5631
XP_006711119                                                           16    5631
NP_060395                                                              16    7355
NP_001123361                                                           16    7355
NP_001913                                                              16    7355
XP_006716870                                                           16    7355
XP_006716869                                                           16    7355
XP_006716868                                                           16    7355
XP_006716867                                                           16    7355
NP_004309                                                              15    9605
NP_009120                                                              15    9605
NP_001158222                                                           15    9605
NP_001010846                                                           15    9605
NP_005683                                                              15    9605
NP_689632                                                              15    9605
XP_006716512                                                           15    9605
XP_005251307                                                           15    9605
XP_005251306                                                           15    9605
XP_005251305                                                           15    9605
XP_005251304                                                           15    9605
XP_005251303                                                           15    9605
XP_006716511                                                           15    9605
XP_005251301                                                           15    9605
XP_005251300                                                           15    9605
XP_005251299                                                           15    9605
XP_005251298                                                           15    9605
XP_005251297                                                           15    9605
XP_005251296                                                           15    9605
XP_005251295                                                           15    9605
XP_005251293                                                           15    9605
XP_005251292                                                           15    9605
XP_005273469                                                           15    9605
XP_005273468                                                           15    9605
XP_005273467                                                           15    9605
XP_005273466                                                           15    9605
XP_006715887                                                           15    9605
XP_005249988                                                           15    9605
XP_005244948                                                           15    9605
NP_005137                                                              15    9605
>XP_006715629
          Length = 1667

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDLAKKRS 8
           RD+ KKRS
Sbjct: 368 RDIGKKRS 375
>NP_078970
          Length = 1667

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDLAKKRS 8
           RD+ KKRS
Sbjct: 368 RDIGKKRS 375
>NP_001243415
          Length = 3269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 536 DIANKRSS 543
>NP_001243417
          Length = 3184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 456 DIANKRSS 463
>NP_004478
          Length = 3259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 531 DIANKRSS 538
>NP_001243416
          Length = 3225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 497 DIANKRSS 504
>NP_055490
          Length = 2017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            RDL K+R S
Sbjct: 1143 RDLGKQRDS 1151
>NP_001278086
          Length = 1559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 848 RDIARRRS 855
>NP_002461
          Length = 1940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLAKK+ S
Sbjct: 204 DLAKKKDS 211
>NP_001181876
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 895 RDIARRRS 902
>NP_937887
          Length = 1512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 801 RDIARRRS 808
>NP_937884
          Length = 1599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 888 RDIARRRS 895
>NP_004944
          Length = 1404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 693 RDIARRRS 700
>NP_001181875
          Length = 1606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 895 RDIARRRS 902
>NP_937885
          Length = 1435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 724 RDIARRRS 731
>NP_886553
          Length = 1600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           RD+A++RS
Sbjct: 889 RDIARRRS 896
>NP_057520
          Length = 1012

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDLAKKRSS 9
           +DL+++RSS
Sbjct: 321 KDLSRRRSS 329
>NP_001261
          Length = 1710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RDLAKKRS 8
            RDLAKK +
Sbjct: 1315 RDLAKKEA 1322
>XP_006721591
          Length = 1940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLAKK+ S
Sbjct: 204 DLAKKKDS 211
>XP_005271924
          Length = 1710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RDLAKKRS 8
            RDLAKK +
Sbjct: 1315 RDLAKKEA 1322
>XP_005271923
          Length = 1798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    RDLAKKRS 8
            RDLAKK +
Sbjct: 1315 RDLAKKEA 1322
>XP_006713654
          Length = 3189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 456 DIANKRSS 463
>XP_006713653
          Length = 3223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 495 DIANKRSS 502
>XP_005247430
          Length = 3228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 495 DIANKRSS 502
>XP_005247429
          Length = 3230

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 497 DIANKRSS 504
>XP_006713652
          Length = 3263

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 530 DIANKRSS 537
>XP_006713651
          Length = 3264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 531 DIANKRSS 538
>XP_006713650
          Length = 3264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 536 DIANKRSS 543
>XP_005247428
          Length = 3269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           D+A KRSS
Sbjct: 536 DIANKRSS 543
>XP_006711123
          Length = 1737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            RDL K+R S
Sbjct: 1105 RDLGKQRDS 1113
>XP_006711122
          Length = 1918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            RDL K+R S
Sbjct: 1105 RDLGKQRDS 1113
>XP_006711121
          Length = 1945

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            RDL K+R S
Sbjct: 1071 RDLGKQRDS 1079
>XP_006711120
          Length = 1972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            RDL K+R S
Sbjct: 1105 RDLGKQRDS 1113
>XP_006711119
          Length = 1979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            RDL K+R S
Sbjct: 1105 RDLGKQRDS 1113
>NP_060395
          Length = 1909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            +DL  KRSS
Sbjct: 1176 KDLRNKRSS 1184
>NP_001123361
          Length = 552

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKR 7
           DLAKKR
Sbjct: 146 DLAKKR 151
>NP_001913
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKR 7
           DLAKKR
Sbjct: 146 DLAKKR 151
>XP_006716870
          Length = 1456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDLAKKRSS 9
           +DL  KRSS
Sbjct: 723 KDLRNKRSS 731
>XP_006716869
          Length = 1722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDLAKKRSS 9
           +DL  KRSS
Sbjct: 989 KDLRNKRSS 997
>XP_006716868
          Length = 1894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            +DL  KRSS
Sbjct: 1225 KDLRNKRSS 1233
>XP_006716867
          Length = 1958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RDLAKKRSS 9
            +DL  KRSS
Sbjct: 1225 KDLRNKRSS 1233
>NP_004309
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 387 DLAEKRRS 394
>NP_009120
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKRSS 9
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>NP_001158222
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 358 DLAEKRRS 365
>NP_001010846
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LAKKRSS 9
           LAK+RSS
Sbjct: 273 LAKRRSS 279
>NP_005683
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKRSS 9
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>NP_689632
          Length = 635

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RDLAKKR 7
          RDL KKR
Sbjct: 39 RDLDKKR 45
>XP_006716512
          Length = 563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 192 DLAEKRRS 199
>XP_005251307
          Length = 696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 325 DLAEKRRS 332
>XP_005251306
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 330 DLAEKRRS 337
>XP_005251305
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 339 DLAEKRRS 346
>XP_005251304
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 340 DLAEKRRS 347
>XP_005251303
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 344 DLAEKRRS 351
>XP_006716511
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 344 DLAEKRRS 351
>XP_005251301
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 353 DLAEKRRS 360
>XP_005251300
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 359 DLAEKRRS 366
>XP_005251299
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 368 DLAEKRRS 375
>XP_005251298
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 372 DLAEKRRS 379
>XP_005251297
          Length = 744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 373 DLAEKRRS 380
>XP_005251296
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 383 DLAEKRRS 390
>XP_005251295
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 387 DLAEKRRS 394
>XP_005251293
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 401 DLAEKRRS 408
>XP_005251292
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DLAKKRSS 9
           DLA+KR S
Sbjct: 402 DLAEKRRS 409
>XP_005273469
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RDLAKKR 7
          RDL KKR
Sbjct: 39 RDLDKKR 45
>XP_005273468
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RDLAKKR 7
          RDL KKR
Sbjct: 39 RDLDKKR 45
>XP_005273467
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RDLAKKR 7
          RDL KKR
Sbjct: 39 RDLDKKR 45
>XP_005273466
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RDLAKKR 7
          RDL KKR
Sbjct: 39 RDLDKKR 45
>XP_006715887
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKRSS 9
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>XP_005249988
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKRSS 9
          DLAKK+++
Sbjct: 4  DLAKKKAA 11
>XP_005244948
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LAKKRSS 9
           LAK+RSS
Sbjct: 273 LAKRRSS 279
>NP_005137
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RDLAKKRS 8
           +DLA+KR+
Sbjct: 214 KDLAEKRA 221
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.117    0.277 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 427,427
Number of extensions: 677
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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