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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001035810                                                           18    1935
NP_000393                                                              18    1935
XP_005274715                                                           18    1935
XP_005274714                                                           18    1935
NP_000008                                                              17    3301
NP_002087                                                              17    4312
NP_000882                                                              16    5631
NP_001261                                                              16    5631
NP_001191351                                                           16    5631
NP_001191347                                                           16    5631
NP_113663                                                              16    5631
XP_005271924                                                           16    5631
XP_005271923                                                           16    5631
XP_005263558                                                           16    5631
NP_001009899                                                           16    7355
NP_002461                                                              16    7355
NP_037493                                                              16    7355
NP_001136087                                                           16    7355
NP_009120                                                              16    7355
NP_003416                                                              16    7355
NP_037530                                                              16    7355
NP_002378                                                              16    7355
NP_001078846                                                           16    7355
NP_001136086                                                           16    7355
NP_001193934                                                           16    7355
NP_001803                                                              16    7355
NP_005683                                                              16    7355
NP_861421                                                              16    7355
XP_005259279                                                           16    7355
XP_005259278                                                           16    7355
XP_006723428                                                           16    7355
XP_006721591                                                           16    7355
XP_006715887                                                           16    7355
XP_005249988                                                           16    7355
XP_005272048                                                           16    7355
XP_006714680                                                           16    7355
XP_006714128                                                           16    7355
XP_006714127                                                           16    7355
XP_005247266                                                           16    7355
XP_005247265                                                           16    7355
XP_006712034                                                           16    7355
XP_005264284                                                           16    7355
XP_005264283                                                           16    7355
XP_005264282                                                           16    7355
NP_001136088                                                           16    7355
NP_056067                                                              16    7355
NP_037494                                                              16    7355
NP_036606                                                              15    9605
NP_689845                                                              15    9605
NP_001116836                                                           15    9605

>NP_001035810
          Length = 515

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLAKKK++
Sbjct: 42 DLAKKKIY 49



>NP_000393
          Length = 545

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLAKKK++
Sbjct: 72 DLAKKKIY 79



>XP_005274715
          Length = 516

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLAKKK++
Sbjct: 42 DLAKKKIY 49



>XP_005274714
          Length = 546

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLAKKK++
Sbjct: 72 DLAKKKIY 79



>NP_000008
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RDLAKKKLF 9
          RD A+K+LF
Sbjct: 46 RDFAEKELF 54



>NP_002087
          Length = 517

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RDLAKKKLF 9
          RDL+ KK++
Sbjct: 49 RDLSNKKIY 57



>NP_000882
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RDLAKKK 7
           RDLA+KK
Sbjct: 359 RDLAEKK 365



>NP_001261
          Length = 1710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RDLAKKK 7
            RDLAKK+
Sbjct: 1315 RDLAKKE 1321



>NP_001191351
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LAKKKLF 9
           LAKKKL+
Sbjct: 415 LAKKKLY 421



>NP_001191347
          Length = 467

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LAKKKLF 9
           LAKKKL+
Sbjct: 452 LAKKKLY 458



>NP_113663
          Length = 854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDLAKKKL 8
           RDL +KKL
Sbjct: 791 RDLLRKKL 798



>XP_005271924
          Length = 1710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RDLAKKK 7
            RDLAKK+
Sbjct: 1315 RDLAKKE 1321



>XP_005271923
          Length = 1798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    RDLAKKK 7
            RDLAKK+
Sbjct: 1315 RDLAKKE 1321



>XP_005263558
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDLAKKKL 8
           RDL +KKL
Sbjct: 770 RDLLRKKL 777



>NP_001009899
          Length = 2245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    DLAKKK 7
            DLAKKK
Sbjct: 1010 DLAKKK 1015



>NP_002461
          Length = 1940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 204 DLAKKK 209



>NP_037493
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>NP_001136087
          Length = 1160

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 738 DLAKKK 743



>NP_009120
          Length = 623

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 DLAKKK 7
         DLAKKK
Sbjct: 4 DLAKKK 9



>NP_003416
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>NP_037530
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>NP_002378
          Length = 829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RDLAKKKL 8
          RDL +KKL
Sbjct: 46 RDLLEKKL 53



>NP_001078846
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDLAKKKL 8
           RDL +KKL
Sbjct: 236 RDLLEKKL 243



>NP_001136086
          Length = 1196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 738 DLAKKK 743



>NP_001193934
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>NP_001803
          Length = 943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 624 DLAKKK 629



>NP_005683
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 DLAKKK 7
         DLAKKK
Sbjct: 4 DLAKKK 9



>NP_861421
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>XP_005259279
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>XP_005259278
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>XP_006723428
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>XP_006721591
          Length = 1940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 204 DLAKKK 209



>XP_006715887
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 DLAKKK 7
         DLAKKK
Sbjct: 4 DLAKKK 9



>XP_005249988
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 DLAKKK 7
         DLAKKK
Sbjct: 4 DLAKKK 9



>XP_005272048
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RDLAKKKL 8
          RDL +KKL
Sbjct: 46 RDLLEKKL 53



>XP_006714680
          Length = 1002

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDLAKKKL 8
           RDL +KKL
Sbjct: 197 RDLLEKKL 204



>XP_006714128
          Length = 730

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 411 DLAKKK 416



>XP_006714127
          Length = 935

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 624 DLAKKK 629



>XP_005247266
          Length = 2189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 954 DLAKKK 959



>XP_005247265
          Length = 2211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 976 DLAKKK 981



>XP_006712034
          Length = 1195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 773 DLAKKK 778



>XP_005264284
          Length = 1196

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 738 DLAKKK 743



>XP_005264283
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 773 DLAKKK 778



>XP_005264282
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 773 DLAKKK 778



>NP_001136088
          Length = 1160

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 738 DLAKKK 743



>NP_056067
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   DLAKKK 7
           DLAKKK
Sbjct: 773 DLAKKK 778



>NP_037494
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  DLAKKKLF 9
          DLA++KL+
Sbjct: 26 DLAQRKLY 33



>NP_036606
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RDLAKKKLF 9
           RDL + KLF
Sbjct: 146 RDLFQMKLF 154



>NP_689845
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RDLAKKK 7
           +DLAK+K
Sbjct: 549 KDLAKRK 555



>NP_001116836
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RDLAKKKLF 9
           +DL+K +LF
Sbjct: 336 KDLSKPQLF 344



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.145    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,022
Number of extensions: 1012
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)