Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     509
NP_671714                                                              20     509
XP_006715890                                                           20     509
XP_005250160                                                           20     509
XP_005250159                                                           20     509
NP_004679                                                              17    2528
XP_005246998                                                           17    2528
NP_001230937                                                           17    4312
NP_004312                                                              17    4312
XP_006712668                                                           17    4312
XP_005247085                                                           17    4312
XP_005247084                                                           17    4312
XP_005247083                                                           17    4312
XP_006712667                                                           17    4312
XP_005247081                                                           17    4312
XP_005247080                                                           17    4312
XP_005247079                                                           17    4312
XP_006712666                                                           17    4312
XP_006712665                                                           17    4312
XP_006712664                                                           17    4312
NP_005529                                                              16    5631
NP_602304                                                              16    7355
NP_001269045                                                           16    7355
XP_006716910                                                           16    7355
XP_006716909                                                           16    7355
XP_005251591                                                           16    7355
XP_006716908                                                           16    7355
XP_006716907                                                           16    7355
XP_006716906                                                           16    7355
XP_006716905                                                           16    7355
XP_006716904                                                           16    7355
XP_006716903                                                           16    7355
NP_009117                                                              15    9605
NP_000353                                                              15    9605
NP_056372                                                              15    9605
NP_055641                                                              15    9605
NP_006026                                                              15    9605
NP_003598                                                              15    9605
NP_057535                                                              15    9605
NP_001137534                                                           15    9605
NP_001137533                                                           15    9605
XP_005260322                                                           15    9605
XP_005260321                                                           15    9605
XP_005260320                                                           15    9605
XP_006723757                                                           15    9605
XP_006723756                                                           15    9605
XP_006723755                                                           15    9605
XP_006723754                                                           15    9605
XP_006723753                                                           15    9605
XP_005260319                                                           15    9605
XP_005268287                                                           15    9605
XP_005268286                                                           15    9605
XP_005268285                                                           15    9605
XP_005268284                                                           15    9605
XP_006711900                                                           15    9605
XP_005273381                                                           15    9605
XP_005273380                                                           15    9605
XP_005273379                                                           15    9605
XP_006711899                                                           15    9605
XP_005273378                                                           15    9605
XP_005273377                                                           15    9605
XP_006711898                                                           15    9605
XP_006711897                                                           15    9605
XP_005273375                                                           15    9605
XP_005273374                                                           15    9605
NP_059995                                                              15    9605
>NP_005742
          Length = 3907

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           R+KLELSQR
Sbjct: 950 REKLELSQR 958
>NP_671714
          Length = 3899

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           R+KLELSQR
Sbjct: 950 REKLELSQR 958
>XP_006715890
          Length = 3860

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           R+KLELSQR
Sbjct: 950 REKLELSQR 958
>XP_005250160
          Length = 3939

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           R+KLELSQR
Sbjct: 950 REKLELSQR 958
>XP_005250159
          Length = 3952

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           R+KLELSQR
Sbjct: 950 REKLELSQR 958
>NP_004679
          Length = 307

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   RDKLELS 7
           RDKLELS
Sbjct: 174 RDKLELS 180
>XP_005246998
          Length = 307

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   RDKLELS 7
           RDKLELS
Sbjct: 174 RDKLELS 180
>NP_001230937
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1499 REKLETAQR 1507
>NP_004312
          Length = 1690

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1398 REKLETAQR 1406
>XP_006712668
          Length = 1782

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1490 REKLETAQR 1498
>XP_005247085
          Length = 1690

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1398 REKLETAQR 1406
>XP_005247084
          Length = 1698

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1406 REKLETAQR 1414
>XP_005247083
          Length = 1699

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1407 REKLETAQR 1415
>XP_006712667
          Length = 1733

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1441 REKLETAQR 1449
>XP_005247081
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1499 REKLETAQR 1507
>XP_005247080
          Length = 1799

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1507 REKLETAQR 1515
>XP_005247079
          Length = 1800

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1508 REKLETAQR 1516
>XP_006712666
          Length = 1816

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1524 REKLETAQR 1532
>XP_006712665
          Length = 1824

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1532 REKLETAQR 1540
>XP_006712664
          Length = 1825

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RDKLELSQR 9
            R+KLE +QR
Sbjct: 1533 REKLETAQR 1541
>NP_005529
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  DKLELSQR 9
          DKL L+QR
Sbjct: 53 DKLHLTQR 60
>NP_602304
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 694 REKTELSQ 701
>NP_001269045
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 694 REKTELSQ 701
>XP_006716910
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 437 REKTELSQ 444
>XP_006716909
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 721 REKTELSQ 728
>XP_005251591
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 704 REKTELSQ 711
>XP_006716908
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 715 REKTELSQ 722
>XP_006716907
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 715 REKTELSQ 722
>XP_006716906
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 715 REKTELSQ 722
>XP_006716905
          Length = 770

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 715 REKTELSQ 722
>XP_006716904
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 721 REKTELSQ 728
>XP_006716903
          Length = 780

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RDKLELSQ 8
           R+K ELSQ
Sbjct: 725 REKTELSQ 732
>NP_009117
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>NP_000353
          Length = 211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DKLELSQR 9
           D+L LSQR
Sbjct: 125 DQLTLSQR 132
>NP_056372
          Length = 1954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    DKLELS 7
            DKLELS
Sbjct: 1649 DKLELS 1654
>NP_055641
          Length = 1638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>NP_006026
          Length = 1711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 452 QEKLELSRK 460
>NP_003598
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>NP_057535
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DKLELSQR 9
           DK+ LSQ+
Sbjct: 942 DKINLSQK 949
>NP_001137534
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DKLELSQR 9
           DK+ LSQ+
Sbjct: 942 DKINLSQK 949
>NP_001137533
          Length = 953

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DKLELSQR 9
           DK+ LSQ+
Sbjct: 942 DKINLSQK 949
>XP_005260322
          Length = 1810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 250 REKMELEMR 258
>XP_005260321
          Length = 2365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 805 REKMELEMR 813
>XP_005260320
          Length = 2370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_006723757
          Length = 2404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_006723756
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_006723755
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_006723754
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_006723753
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_005260319
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RDKLELSQR 9
           R+K+EL  R
Sbjct: 882 REKMELEMR 890
>XP_005268287
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 452 QEKLELSRK 460
>XP_005268286
          Length = 1685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 452 QEKLELSRK 460
>XP_005268285
          Length = 1702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 452 QEKLELSRK 460
>XP_005268284
          Length = 1728

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 452 QEKLELSRK 460
>XP_006711900
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273381
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273380
          Length = 1751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273379
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_006711899
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273378
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273377
          Length = 1794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_006711898
          Length = 1797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_006711897
          Length = 1816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273375
          Length = 1829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>XP_005273374
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RDKLELSQR 9
           ++KLELS++
Sbjct: 453 QEKLELSRK 461
>NP_059995
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   RDKLELSQ 8
           RDK  LSQ
Sbjct: 465 RDKASLSQ 472
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.131    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,338
Number of extensions: 829
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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