Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              18    1482
NP_478126                                                              18    1482
NP_998818                                                              17    3301
XP_005272989                                                           17    3301
NP_001274448                                                           17    4312
NP_001274449                                                           17    4312
NP_068659                                                              17    4312
NP_068658                                                              17    4312
NP_004349                                                              17    4312
NP_001274447                                                           17    4312
NP_001274453                                                           17    4312
NP_001274445                                                           17    4312
NP_001274451                                                           17    4312
NP_001274446                                                           17    4312
NP_001693                                                              17    4312
XP_005251072                                                           17    4312
NP_059127                                                              16    5631
NP_001035186                                                           16    5631
NP_001265546                                                           16    5631
NP_001265545                                                           16    5631
NP_004327                                                              16    5631
NP_001035188                                                           16    5631
XP_005250588                                                           16    5631
XP_005250586                                                           16    5631
XP_005250587                                                           16    5631
NP_001035187                                                           16    5631
NP_076438                                                              16    5631
NP_848604                                                              16    7355
NP_078934                                                              16    7355
NP_001116108                                                           16    7355
NP_068580                                                              16    7355
NP_004409                                                              16    7355
XP_003960325                                                           16    7355
XP_005257244                                                           16    7355
XP_003119208                                                           16    7355
XP_003119825                                                           16    7355
NP_006209                                                              15    9605
NP_001092740                                                           15    9605
NP_001161814                                                           15    9605
NP_001259017                                                           15    9605
NP_071924                                                              15    9605
NP_001004125                                                           15    9605
NP_001259016                                                           15    9605
NP_056380                                                              15    9605
NP_055746                                                              15    9605
NP_036298                                                              15    9605
NP_001161811                                                           15    9605
NP_689787                                                              15    9605
NP_001161813                                                           15    9605
NP_001161812                                                           15    9605
NP_005062                                                              15    9605
XP_006724050                                                           15    9605
XP_006723153                                                           15    9605
XP_005258727                                                           15    9605
XP_005258726                                                           15    9605
XP_006722907                                                           15    9605
XP_006722906                                                           15    9605
XP_006722905                                                           15    9605
XP_005252046                                                           15    9605
XP_006716817                                                           15    9605
XP_005251496                                                           15    9605
XP_006713721                                                           15    9605
>NP_004251
          Length = 1208

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RALRSRLL 8
           RALRSRLL
Sbjct: 367 RALRSRLL 374
>NP_478126
          Length = 272

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR RLLC
Sbjct: 91 ALRGRLLC 98
>NP_998818
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  RALRSRLLC 9
          RALRS  LC
Sbjct: 81 RALRSYALC 89
>XP_005272989
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  RALRSRLLC 9
          RALRS  LC
Sbjct: 81 RALRSYALC 89
>NP_001274448
          Length = 468

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 257 RVLRSKSLC 265
>NP_001274449
          Length = 468

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 257 RVLRSKSLC 265
>NP_068659
          Length = 580

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 369 RVLRSKSLC 377
>NP_068658
          Length = 539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 328 RVLRSKSLC 336
>NP_004349
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 355 RVLRSKSLC 363
>NP_001274447
          Length = 489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 278 RVLRSKSLC 286
>NP_001274453
          Length = 388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 177 RVLRSKSLC 185
>NP_001274445
          Length = 516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 305 RVLRSKSLC 313
>NP_001274451
          Length = 427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 216 RVLRSKSLC 224
>NP_001274446
          Length = 502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R LRS+ LC
Sbjct: 291 RVLRSKSLC 299
>NP_001693
          Length = 1584

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALRSRLLC 9
           ALR+R LC
Sbjct: 916 ALRTRCLC 923
>XP_005251072
          Length = 1586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALRSRLLC 9
           ALR+R LC
Sbjct: 913 ALRTRCLC 920
>NP_059127
          Length = 489

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALRSRLLC 9
           ALR R LC
Sbjct: 420 ALRQRTLC 427
>NP_001035186
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>NP_001265546
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALRSRLL 8
            RALR+RL+
Sbjct: 1010 RALRNRLI 1017
>NP_001265545
          Length = 1065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALRSRLL 8
            RALR+RL+
Sbjct: 1047 RALRNRLI 1054
>NP_004327
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALRSRLL 8
            RALR+RL+
Sbjct: 1067 RALRNRLI 1074
>NP_001035188
          Length = 225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>XP_005250588
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>XP_005250586
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>XP_005250587
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>NP_001035187
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>NP_076438
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALR R+LC
Sbjct: 64 ALRFRVLC 71
>NP_848604
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALRSRL 7
           RALRSR+
Sbjct: 347 RALRSRI 353
>NP_078934
          Length = 1081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ALRSRLLC 9
           A+R R+LC
Sbjct: 262 AIRIRILC 269
>NP_001116108
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALRSRLLC 9
           ALR RL C
Sbjct: 435 ALRQRLKC 442
>NP_068580
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ALRSRLLC 9
          ALR RL C
Sbjct: 69 ALRQRLKC 76
>NP_004409
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  RALRSRLL 8
          RALR+RL+
Sbjct: 74 RALRTRLV 81
>XP_003960325
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALRS+L C
Sbjct: 20 ALRSQLRC 27
>XP_005257244
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALRSRL 7
           RALRSR+
Sbjct: 349 RALRSRI 355
>XP_003119208
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALRS+L C
Sbjct: 20 ALRSQLRC 27
>XP_003119825
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ALRSRLLC 9
          ALRS+L C
Sbjct: 20 ALRSQLRC 27
>NP_006209
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ALRSRLLC 9
           ALR ++LC
Sbjct: 333 ALRIKILC 340
>NP_001092740
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALRSRL 7
           +ALRSRL
Sbjct: 188 KALRSRL 194
>NP_001161814
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R++RS L C
Sbjct: 181 RSMRSALCC 189
>NP_001259017
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RALRSRL 7
          RALR+RL
Sbjct: 33 RALRTRL 39
>NP_071924
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RALRSRLLC 9
           RALR  L C
Sbjct: 435 RALRKSLKC 443
>NP_001004125
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALRSRL 7
           RALR+RL
Sbjct: 155 RALRARL 161
>NP_001259016
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RALRSRL 7
          RALR+RL
Sbjct: 33 RALRTRL 39
>NP_056380
          Length = 1812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ALRSRLLC 9
          A RSR LC
Sbjct: 21 AARSRKLC 28
>NP_055746
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALRSRLLC 9
           ALR RL C
Sbjct: 319 ALRPRLSC 326
>NP_036298
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LRSRLLC 9
           LRS L+C
Sbjct: 614 LRSNLIC 620
>NP_001161811
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R++RS L C
Sbjct: 344 RSMRSALCC 352
>NP_689787
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R++RS L C
Sbjct: 346 RSMRSALCC 354
>NP_001161813
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R++RS L C
Sbjct: 277 RSMRSALCC 285
>NP_001161812
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RALRSRLLC 9
           R++RS L C
Sbjct: 346 RSMRSALCC 354
>NP_005062
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RALRSRL 7
          RALR+RL
Sbjct: 33 RALRTRL 39
>XP_006724050
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  ALRSRLLC 9
          A RSR LC
Sbjct: 21 AARSRKLC 28
>XP_006723153
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALRSRLLC 9
           ALR RL C
Sbjct: 192 ALRPRLSC 199
>XP_005258727
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALRSRLLC 9
           ALR RL C
Sbjct: 319 ALRPRLSC 326
>XP_005258726
          Length = 881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALRSRLLC 9
           ALR RL C
Sbjct: 319 ALRPRLSC 326
>XP_006722907
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RALRSRL 7
          RALR+RL
Sbjct: 33 RALRTRL 39
>XP_006722906
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RALRSRL 7
          RALR+RL
Sbjct: 33 RALRTRL 39
>XP_006722905
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  RALRSRL 7
          RALR+RL
Sbjct: 33 RALRTRL 39
>XP_005252046
          Length = 514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALRSRL 7
           +ALRSRL
Sbjct: 202 KALRSRL 208
>XP_006716817
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LRSRLLC 9
           LRS L+C
Sbjct: 139 LRSNLIC 145
>XP_005251496
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LRSRLLC 9
           LRS L+C
Sbjct: 614 LRSNLIC 620
>XP_006713721
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ALRSRLLC 9
           ALR ++LC
Sbjct: 333 ALRIKILC 340
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.146    0.459 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 389,657
Number of extensions: 597
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)

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