Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1482
XP_006716142                                                           18    1482
XP_005250088                                                           18    1482
XP_006716141                                                           18    1482
XP_005250085                                                           18    1482
XP_006716140                                                           18    1482
XP_005250084                                                           18    1482
XP_005250083                                                           18    1482
XP_005250082                                                           18    1482
NP_001129201                                                           17    4312
NP_001129204                                                           17    4312
NP_005479                                                              17    4312
NP_001129202                                                           17    4312
NP_057726                                                              16    5631
XP_005254495                                                           16    5631
NP_004371                                                              16    7355
NP_001073315                                                           16    7355
NP_982284                                                              16    7355
NP_006083                                                              16    7355
NP_443080                                                              16    7355
XP_006726390                                                           16    7355
XP_006726389                                                           16    7355
XP_006726388                                                           16    7355
XP_006726387                                                           16    7355
XP_005259434                                                           16    7355
XP_005255182                                                           16    7355
XP_006720911                                                           16    7355
XP_005255181                                                           16    7355
XP_005249633                                                           16    7355
XP_006715700                                                           16    7355
XP_006715699                                                           16    7355
XP_005249632                                                           16    7355
XP_005249631                                                           16    7355
XP_005249630                                                           16    7355
XP_006715698                                                           16    7355
XP_006715697                                                           16    7355
XP_005249629                                                           16    7355
XP_006715696                                                           16    7355
XP_005249625                                                           16    7355
XP_005245099                                                           16    7355
XP_005245098                                                           16    7355
XP_005245097                                                           16    7355
XP_006711142                                                           16    7355
XP_006711141                                                           16    7355
XP_006711140                                                           16    7355
XP_006710131                                                           16    7355
XP_006710130                                                           16    7355
XP_006710129                                                           16    7355
XP_006710128                                                           16    7355
NP_940820                                                              15    9605
NP_001028776                                                           15    9605
NP_001028777                                                           15    9605
NP_055266                                                              15    9605
NP_060915                                                              15    9605
NP_982298                                                              15    9605
NP_001275716                                                           15    9605
NP_001275715                                                           15    9605
NP_001275717                                                           15    9605
NP_001275718                                                           15    9605
NP_001076437                                                           15    9605
NP_004775                                                              15    9605
NP_001028723                                                           15    9605
XP_005256523                                                           15    9605
XP_005256520                                                           15    9605
XP_005256519                                                           15    9605
XP_006721515                                                           15    9605
XP_005256518                                                           15    9605
XP_005249758                                                           15    9605
XP_006715751                                                           15    9605
XP_005249757                                                           15    9605
XP_006715750                                                           15    9605
XP_006714479                                                           15    9605
NP_071745                                                              15    9605
NP_001123612                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3423 RALQQRMEM 3431
>XP_006716142
          Length = 4927

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>XP_005250088
          Length = 4928

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>XP_006716141
          Length = 4959

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>XP_005250085
          Length = 4979

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>XP_006716140
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>XP_005250084
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>XP_005250083
          Length = 4982

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3439 RALQQRMEM 3447
>XP_005250082
          Length = 4983

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RALQQRMLM 9
            RALQQRM M
Sbjct: 3440 RALQQRMEM 3448
>NP_001129201
          Length = 460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR+L
Sbjct: 229 RAMQQRVL 236
>NP_001129204
          Length = 493

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR+L
Sbjct: 262 RAMQQRVL 269
>NP_005479
          Length = 492

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR+L
Sbjct: 262 RAMQQRVL 269
>NP_001129202
          Length = 447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR+L
Sbjct: 217 RAMQQRVL 224
>NP_057726
          Length = 3674

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           +ALQQR+L
Sbjct: 412 QALQQRLL 419
>XP_005254495
          Length = 3694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           +ALQQR+L
Sbjct: 432 QALQQRLL 439
>NP_004371
          Length = 2442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALQQRML 8
            +ALQQR+L
Sbjct: 2289 QALQQRIL 2296
>NP_001073315
          Length = 2404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALQQRML 8
            +ALQQR+L
Sbjct: 2251 QALQQRIL 2258
>NP_982284
          Length = 1478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALQQRMLM 9
           +LQQ MLM
Sbjct: 902 SLQQEMLM 909
>NP_006083
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>NP_443080
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           R LQQR+L
Sbjct: 231 RELQQRLL 238
>XP_006726390
          Length = 1353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 648 QGLQQRML 655
>XP_006726389
          Length = 1471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 766 QGLQQRML 773
>XP_006726388
          Length = 1489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 784 QGLQQRML 791
>XP_006726387
          Length = 1497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 832 QGLQQRML 839
>XP_005259434
          Length = 278

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           R LQQR+L
Sbjct: 166 RELQQRLL 173
>XP_005255182
          Length = 2303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALQQRML 8
            +ALQQR+L
Sbjct: 2150 QALQQRIL 2157
>XP_006720911
          Length = 2355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALQQRML 8
            +ALQQR+L
Sbjct: 2202 QALQQRIL 2209
>XP_005255181
          Length = 2427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RALQQRML 8
            +ALQQR+L
Sbjct: 2274 QALQQRIL 2281
>XP_005249633
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 120 RALQDRLL 127
>XP_006715700
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_006715699
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_005249632
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_005249631
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_005249630
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_006715698
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_006715697
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_005249629
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_006715696
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_005249625
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ R+L
Sbjct: 368 RALQDRLL 375
>XP_005245099
          Length = 1462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALQQRMLM 9
           +LQQ MLM
Sbjct: 886 SLQQEMLM 893
>XP_005245098
          Length = 1473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALQQRMLM 9
           +LQQ MLM
Sbjct: 897 SLQQEMLM 904
>XP_005245097
          Length = 1489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALQQRMLM 9
           +LQQ MLM
Sbjct: 913 SLQQEMLM 920
>XP_006711142
          Length = 1471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 766 QGLQQRML 773
>XP_006711141
          Length = 1489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 784 QGLQQRML 791
>XP_006711140
          Length = 1497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 832 QGLQQRML 839
>XP_006710131
          Length = 1353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 648 QGLQQRML 655
>XP_006710130
          Length = 1471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 766 QGLQQRML 773
>XP_006710129
          Length = 1489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 784 QGLQQRML 791
>XP_006710128
          Length = 1497

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           + LQQRML
Sbjct: 832 QGLQQRML 839
>NP_940820
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 674 RAIQRRLL 681
>NP_001028776
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 639 RAIQRRLL 646
>NP_001028777
          Length = 882

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 669 RAIQRRLL 676
>NP_055266
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 634 RAIQRRLL 641
>NP_060915
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RALQQRML 8
          RAL+QR L
Sbjct: 56 RALRQRQL 63
>NP_982298
          Length = 187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RALQQRML 8
          RAL+QR L
Sbjct: 56 RALRQRQL 63
>NP_001275716
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 221 RAMQQRIV 228
>NP_001275715
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 213 RAMQQRIV 220
>NP_001275717
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 168 RAMQQRIV 175
>NP_001275718
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 118 RAMQQRIV 125
>NP_001076437
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 266 RAMQQRIV 273
>NP_004775
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALQQRMLM 9
           RALQ+R L+
Sbjct: 736 RALQKRCLV 744
>NP_001028723
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 216 RAMQQRIV 223
>XP_005256523
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 168 RAMQQRIV 175
>XP_005256520
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 266 RAMQQRIV 273
>XP_005256519
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 221 RAMQQRIV 228
>XP_006721515
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 233 RAMQQRIV 240
>XP_005256518
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+QQR++
Sbjct: 266 RAMQQRIV 273
>XP_005249758
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 674 RAIQRRLL 681
>XP_006715751
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 583 RAIQRRLL 590
>XP_005249757
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 674 RAIQRRLL 681
>XP_006715750
          Length = 887

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RALQQRML 8
           RA+Q+R+L
Sbjct: 674 RAIQRRLL 681
>XP_006714479
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALQQRMLM 9
           RALQ+R L+
Sbjct: 736 RALQKRCLV 744
>NP_071745
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ+R L
Sbjct: 578 RALQERYL 585
>NP_001123612
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RALQQRML 8
           RALQ+R L
Sbjct: 578 RALQERYL 585
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.139    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,828
Number of extensions: 492
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)

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