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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001074011                                                           17    4312
NP_001257449                                                           16    5631
NP_055807                                                              16    5631
NP_001120936                                                           16    5631
NP_054722                                                              16    5631
XP_005256326                                                           16    5631
XP_005267488                                                           16    5631
XP_005267487                                                           16    5631
NP_001137300                                                           16    7355
NP_002325                                                              16    7355
NP_067637                                                              16    7355
NP_036533                                                              16    7355
XP_005261968                                                           16    7355
XP_005261966                                                           16    7355
XP_005261967                                                           16    7355
XP_006724476                                                           16    7355
XP_005261965                                                           16    7355
XP_006718294                                                           16    7355
XP_005252980                                                           16    7355
NP_006444                                                              16    7355
NP_005912                                                              15    9605
NP_001159417                                                           15    9605
NP_060501                                                              15    9605
NP_057740                                                              15    9605
NP_065073                                                              15    9605
XP_005262032                                                           15    9605
XP_005262031                                                           15    9605
XP_005262030                                                           15    9605
XP_006715582                                                           15    9605
XP_005248577                                                           15    9605
XP_005248576                                                           15    9605
XP_005264894                                                           15    9605
XP_006710132                                                           15    9605

>NP_001074011
          Length = 1133

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AHSRSINS 9
           +H+RS+NS
Sbjct: 731 SHTRSLNS 738



>NP_001257449
          Length = 1068

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AHSRSIN 8
           AHS SIN
Sbjct: 200 AHSESIN 206



>NP_055807
          Length = 1078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AHSRSIN 8
           AHS SIN
Sbjct: 200 AHSESIN 206



>NP_001120936
          Length = 3925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    RAHSRS 6
            RAHSRS
Sbjct: 2752 RAHSRS 2757



>NP_054722
          Length = 1227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AHSRSINS 9
           AH RS+N+
Sbjct: 654 AHERSLNT 661



>XP_005256326
          Length = 1192

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AHSRSINS 9
           AH RS+N+
Sbjct: 619 AHERSLNT 626



>XP_005267488
          Length = 1078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AHSRSIN 8
           AHS SIN
Sbjct: 200 AHSESIN 206



>XP_005267487
          Length = 1078

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AHSRSIN 8
           AHS SIN
Sbjct: 200 AHSESIN 206



>NP_001137300
          Length = 302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HSRSINS 9
           HSRS++S
Sbjct: 296 HSRSVSS 302



>NP_002325
          Length = 1905

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HSRSINS 9
           H++SINS
Sbjct: 659 HTKSINS 665



>NP_067637
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HSRSINS 9
           HSRS++S
Sbjct: 384 HSRSVSS 390



>NP_036533
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAHSRSINS 9
            RAH+ S+N+
Sbjct: 1779 RAHTDSLNT 1787



>XP_005261968
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAHSRSINS 9
            RAH+ S+N+
Sbjct: 1779 RAHTDSLNT 1787



>XP_005261966
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAHSRSINS 9
            RAH+ S+N+
Sbjct: 1779 RAHTDSLNT 1787



>XP_005261967
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAHSRSINS 9
            RAH+ S+N+
Sbjct: 1779 RAHTDSLNT 1787



>XP_006724476
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAHSRSINS 9
            RAH+ S+N+
Sbjct: 1779 RAHTDSLNT 1787



>XP_005261965
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAHSRSINS 9
            RAH+ S+N+
Sbjct: 1861 RAHTDSLNT 1869



>XP_006718294
          Length = 1808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HSRSINS 9
           H++SINS
Sbjct: 659 HTKSINS 665



>XP_005252980
          Length = 1809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   HSRSINS 9
           H++SINS
Sbjct: 659 HTKSINS 665



>NP_006444
          Length = 808

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   RAHSRSINS 9
           R H + INS
Sbjct: 476 RCHDKDINS 484



>NP_005912
          Length = 1512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAHSRSINS 9
           R HS+ +NS
Sbjct: 961 RPHSQCLNS 969



>NP_001159417
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RAHSRSIN 8
          RAH RS++
Sbjct: 40 RAHLRSVS 47



>NP_060501
          Length = 1151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RAHSRSINS 9
            +AHS  INS
Sbjct: 1007 QAHSCGINS 1015



>NP_057740
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RAHSRSINS 9
          R HS  INS
Sbjct: 79 RIHSLQINS 87



>NP_065073
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   HSRSINS 9
           H RSIN+
Sbjct: 151 HQRSINT 157



>XP_005262032
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RAHSRSINS 9
          R HS  INS
Sbjct: 79 RIHSLQINS 87



>XP_005262031
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RAHSRSINS 9
          R HS  INS
Sbjct: 79 RIHSLQINS 87



>XP_005262030
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  RAHSRSINS 9
          R HS  INS
Sbjct: 41 RIHSLQINS 49



>XP_006715582
          Length = 2106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  HSRSINS 9
          H RSIN+
Sbjct: 80 HQRSINT 86



>XP_005248577
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAHSRSINS 9
           R HS+ +NS
Sbjct: 798 RPHSQCLNS 806



>XP_005248576
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAHSRSINS 9
           R HS+ +NS
Sbjct: 824 RPHSQCLNS 832



>XP_005264894
          Length = 1070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RAHSRSINS 9
           +AHS  INS
Sbjct: 926 QAHSCGINS 934



>XP_006710132
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RAHSRSIN 8
          RAH RS++
Sbjct: 40 RAHLRSVS 47



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.111    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 562,119
Number of extensions: 797
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)