Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055365                                                              19     869
NP_037506                                                              16    5631
NP_001155901                                                           16    5631
NP_054859                                                              15    9605
NP_001120679                                                           15    9605
NP_954635                                                              15    9605
NP_000679                                                              15    9605
NP_001361                                                              15    9605
XP_005265002                                                           15    9605
XP_005265001                                                           15    9605
XP_006712620                                                           15    9605
XP_005246688                                                           15    9605
XP_005246689                                                           15    9605
XP_006712019                                                           15    9605
>NP_055365
          Length = 1032

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QYSQSLIAK 9
           QYSQSLI K
Sbjct: 408 QYSQSLIEK 416
>NP_037506
          Length = 868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QYSQSLIAK 9
           +Y QS++AK
Sbjct: 257 EYHQSILAK 265
>NP_001155901
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QYSQSLIAK 9
           +Y QS++AK
Sbjct: 262 EYHQSILAK 270
>NP_054859
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YSQSLIA 8
           YSQ LIA
Sbjct: 349 YSQDLIA 355
>NP_001120679
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YSQSLIA 8
           YSQ LIA
Sbjct: 349 YSQDLIA 355
>NP_954635
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YSQSLIAK 9
           YS SLI K
Sbjct: 235 YSDSLITK 242
>NP_000679
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YSQSLIAK 9
           YS SLI K
Sbjct: 235 YSDSLITK 242
>NP_001361
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QYSQSLI 7
            QY QSLI
Sbjct: 3012 QYRQSLI 3018
>XP_005265002
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YSQSLIAK 9
           YS SLI K
Sbjct: 235 YSDSLITK 242
>XP_005265001
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   YSQSLIAK 9
           YS SLI K
Sbjct: 252 YSDSLITK 259
>XP_006712620
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YSQSLIA 8
           YSQ LIA
Sbjct: 349 YSQDLIA 355
>XP_005246688
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YSQSLIA 8
           YSQ LIA
Sbjct: 349 YSQDLIA 355
>XP_005246689
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   YSQSLIA 8
           YSQ LIA
Sbjct: 349 YSQDLIA 355
>XP_006712019
          Length = 4158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QYSQSLI 7
            QY QSLI
Sbjct: 3012 QYRQSLI 3018
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.116    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 317,845
Number of extensions: 330
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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