Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1935
XP_005262424                                                           18    1935
XP_006720531                                                           17    4312
XP_005254344                                                           17    4312
NP_056993                                                              15    9605
NP_004230                                                              15    9605
NP_031382                                                              15    9605
XP_005268271                                                           15    9605
XP_005268270                                                           15    9605
XP_006720384                                                           15    9605
XP_005250289                                                           15    9605
>NP_722576
          Length = 3080

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QYQLTLLVN 9
            Q QLTLLVN
Sbjct: 2364 QDQLTLLVN 2372
>XP_005262424
          Length = 2875

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QYQLTLLVN 9
            Q QLTLLVN
Sbjct: 2159 QDQLTLLVN 2167
>XP_006720531
          Length = 415

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YQLTLLVN 9
           Y LTL+VN
Sbjct: 217 YPLTLIVN 224
>XP_005254344
          Length = 556

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YQLTLLVN 9
           Y LTL+VN
Sbjct: 358 YPLTLIVN 365
>NP_056993
          Length = 2371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    QYQLTLLVN 9
            QY  TLL N
Sbjct: 1760 QYYFTLLEN 1768
>NP_004230
          Length = 1979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QYQLTLLVN 9
           Q QLT L+N
Sbjct: 803 QKQLTQLIN 811
>NP_031382
          Length = 1761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QYQLTLLVN 9
          Q+QLTL ++
Sbjct: 2  QFQLTLFLH 10
>XP_005268271
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QYQLTLLVN 9
           Q QLT L+N
Sbjct: 361 QKQLTQLIN 369
>XP_005268270
          Length = 1950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QYQLTLLVN 9
           Q QLT L+N
Sbjct: 774 QKQLTQLIN 782
>XP_006720384
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QYQLTLLVN 9
           Q QLT L+N
Sbjct: 802 QKQLTQLIN 810
>XP_005250289
          Length = 1761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QYQLTLLVN 9
          Q+QLTL ++
Sbjct: 2  QFQLTLFLH 10
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.138    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 408,793
Number of extensions: 708
Number of successful extensions: 11
Number of sequences better than 10000.0: 11
Number of HSP's gapped: 11
Number of HSP's successfully gapped: 11
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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