Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_667338                                                              17    2528
NP_001159608                                                           17    2528
XP_006713923                                                           17    2528
XP_006713922                                                           17    2528
NP_878917                                                              17    3301
NP_878914                                                              17    3301
NP_878918                                                              17    3301
NP_055995                                                              17    3301
XP_005267517                                                           17    3301
XP_005267516                                                           17    3301
XP_005267515                                                           17    3301
XP_005267514                                                           17    3301
XP_005267513                                                           17    3301
XP_005267512                                                           17    3301
XP_005267511                                                           17    3301
NP_079225                                                              15    9605
XP_006714375                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSKDVMAM 9
            VSKDVMAM
Sbjct: 1930 VSKDVMAM 1937
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VSKDVMAM 9
            VSKDVMAM
Sbjct: 1725 VSKDVMAM 1732
>NP_667338
          Length = 1308

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QVSKDVMAM 9
           Q+SKD++A+
Sbjct: 401 QISKDIIAL 409
>NP_001159608
          Length = 1228

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QVSKDVMAM 9
           Q+SKD++A+
Sbjct: 321 QISKDIIAL 329
>XP_006713923
          Length = 1228

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QVSKDVMAM 9
           Q+SKD++A+
Sbjct: 321 QISKDIIAL 329
>XP_006713922
          Length = 1262

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QVSKDVMAM 9
           Q+SKD++A+
Sbjct: 401 QISKDIIAL 409
>NP_878917
          Length = 556

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QVSKDVMAM 9
           QVS+D+MA+
Sbjct: 430 QVSQDLMAL 438
>NP_878914
          Length = 429

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QVSKDVMAM 9
           QVS+D+MA+
Sbjct: 304 QVSQDLMAL 312
>NP_878918
          Length = 6907

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6782 QVSQDLMAL 6790
>NP_055995
          Length = 6885

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6759 QVSQDLMAL 6767
>XP_005267517
          Length = 6883

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6757 QVSQDLMAL 6765
>XP_005267516
          Length = 6884

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6759 QVSQDLMAL 6767
>XP_005267515
          Length = 6899

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6773 QVSQDLMAL 6781
>XP_005267514
          Length = 6908

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6782 QVSQDLMAL 6790
>XP_005267513
          Length = 6921

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6796 QVSQDLMAL 6804
>XP_005267512
          Length = 6922

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6796 QVSQDLMAL 6804
>XP_005267511
          Length = 6922

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QVSKDVMAM 9
            QVS+D+MA+
Sbjct: 6796 QVSQDLMAL 6804
>NP_079225
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    QVSKDV 6
            QVSKDV
Sbjct: 1148 QVSKDV 1153
>XP_006714375
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    QVSKDV 6
            QVSKDV
Sbjct: 1164 QVSKDV 1169
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.117    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 359,901
Number of extensions: 201
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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