Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
NP_689777                                                              16    5631
NP_060360                                                              16    5631
NP_071736                                                              16    5631
XP_005250858                                                           16    5631
XP_005250857                                                           16    5631
NP_001035700                                                           16    7355
NP_004299                                                              16    7355
NP_078856                                                              16    7355
NP_005633                                                              15    9605
>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVGVQKQVL 9
            QV VQKQVL
Sbjct: 1531 QVEVQKQVL 1539
>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QVGVQKQVL 9
           QV VQKQVL
Sbjct: 183 QVEVQKQVL 191
>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVGVQKQVL 9
            QV VQKQVL
Sbjct: 1183 QVEVQKQVL 1191
>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVGVQKQVL 9
            QV VQKQVL
Sbjct: 1525 QVEVQKQVL 1533
>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVGVQKQVL 9
            QV VQKQVL
Sbjct: 1531 QVEVQKQVL 1539
>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVGVQKQVL 9
            QV VQKQVL
Sbjct: 1531 QVEVQKQVL 1539
>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVGVQKQVL 9
            QV VQKQVL
Sbjct: 1531 QVEVQKQVL 1539
>NP_689777
          Length = 3997

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GVQKQVL 9
            GVQKQ++
Sbjct: 2695 GVQKQII 2701
>NP_060360
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GVQKQVL 9
            GVQKQ++
Sbjct: 2720 GVQKQII 2726
>NP_071736
          Length = 243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QVGVQKQVL 9
           Q+GV +QVL
Sbjct: 115 QLGVPRQVL 123
>XP_005250858
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GVQKQVL 9
            GVQKQ++
Sbjct: 2720 GVQKQII 2726
>XP_005250857
          Length = 4022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GVQKQVL 9
            GVQKQ++
Sbjct: 2720 GVQKQII 2726
>NP_001035700
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVGVQKQVL 9
           ++G++K+VL
Sbjct: 204 KIGIKKEVL 212
>NP_004299
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QVGVQKQVL 9
           Q+G+ +QVL
Sbjct: 203 QLGIPRQVL 211
>NP_078856
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVGVQKQVL 9
           ++G++K+VL
Sbjct: 255 KIGIKKEVL 263
>NP_005633
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   VGVQKQV 8
           +G+QKQ+
Sbjct: 279 MGIQKQI 285
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.134    0.330 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 461,555
Number of extensions: 537
Number of successful extensions: 16
Number of sequences better than 10000.0: 16
Number of HSP's gapped: 16
Number of HSP's successfully gapped: 16
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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