Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1482
XP_005262424                                                           18    1482
NP_071900                                                              16    5631
XP_006714967                                                           16    5631
XP_006714966                                                           16    5631
XP_006714964                                                           16    5631
XP_005266016                                                           16    5631
NP_001093321                                                           16    7355
NP_001038945                                                           16    7355
NP_006176                                                              16    7355
NP_001273490                                                           16    7355
XP_006723005                                                           16    7355
XP_006718633                                                           16    7355
XP_006718632                                                           16    7355
XP_006718631                                                           16    7355
XP_006718630                                                           16    7355
XP_006718629                                                           16    7355
XP_006718628                                                           16    7355
XP_006718627                                                           16    7355
XP_006718626                                                           16    7355
XP_006718625                                                           16    7355
NP_001273988                                                           15    9605
NP_056153                                                              15    9605
NP_055867                                                              15    9605
NP_000370                                                              15    9605
NP_005135                                                              15    9605
NP_060881                                                              15    9605
NP_055315                                                              15    9605
NP_001153566                                                           15    9605
NP_060943                                                              15    9605
NP_065811                                                              15    9605
NP_060899                                                              15    9605
XP_006725524                                                           15    9605
XP_006725523                                                           15    9605
XP_005276828                                                           15    9605
XP_006726279                                                           15    9605
XP_005262461                                                           15    9605
XP_006723795                                                           15    9605
XP_006723794                                                           15    9605
XP_006723793                                                           15    9605
XP_006723792                                                           15    9605
XP_006723791                                                           15    9605
XP_006723790                                                           15    9605
XP_006716430                                                           15    9605
XP_005273626                                                           15    9605
XP_006715736                                                           15    9605
XP_006715735                                                           15    9605
XP_005249722                                                           15    9605
XP_006715734                                                           15    9605
XP_006715733                                                           15    9605
XP_006715608                                                           15    9605
XP_005248815                                                           15    9605
XP_006714722                                                           15    9605
XP_006714721                                                           15    9605
XP_006712712                                                           15    9605
XP_006712711                                                           15    9605
XP_006712710                                                           15    9605
XP_006712709                                                           15    9605
NP_001156752                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QVEETSTNA 9
            QVEETST A
Sbjct: 1176 QVEETSTYA 1184
>XP_005262424
          Length = 2875

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QVEETSTNA 9
           QVEETST A
Sbjct: 971 QVEETSTYA 979
>NP_071900
          Length = 2696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EETSTNA 9
           EET TNA
Sbjct: 185 EETQTNA 191
>XP_006714967
          Length = 1327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EETSTNA 9
           EET TNA
Sbjct: 185 EETQTNA 191
>XP_006714966
          Length = 1499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EETSTNA 9
           EET TNA
Sbjct: 185 EETQTNA 191
>XP_006714964
          Length = 2696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EETSTNA 9
           EET TNA
Sbjct: 185 EETQTNA 191
>XP_005266016
          Length = 2696

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EETSTNA 9
           EET TNA
Sbjct: 185 EETQTNA 191
>NP_001093321
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ETSTNA 9
           ETSTNA
Sbjct: 388 ETSTNA 393
>NP_001038945
          Length = 474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ETSTNA 9
           ETSTNA
Sbjct: 388 ETSTNA 393
>NP_006176
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>NP_001273490
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006723005
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   VEETSTN 8
           VEE STN
Sbjct: 212 VEENSTN 218
>XP_006718633
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718632
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718631
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718630
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718629
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718628
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718627
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718626
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>XP_006718625
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QVEETSTNA 9
            Q+E TST A
Sbjct: 1347 QLEHTSTQA 1355
>NP_001273988
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1563 VEETST 1568
>NP_056153
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 127 LDETSSNA 134
>NP_055867
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1597 VEETST 1602
>NP_000370
          Length = 1333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    VEETSTN 8
            + ETSTN
Sbjct: 1064 ISETSTN 1070
>NP_005135
          Length = 1189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QVEETSTNA 9
           Q E+T+TN+
Sbjct: 528 QEEDTATNS 536
>NP_060881
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QVEETSTNA 9
           Q E+T+TN+
Sbjct: 528 QEEDTATNS 536
>NP_055315
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QVEETS 6
           QVEETS
Sbjct: 354 QVEETS 359
>NP_001153566
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QVEETSTNA 9
          +VEE  TNA
Sbjct: 20 KVEEEHTNA 28
>NP_060943
          Length = 140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QVEETSTNA 9
          +VEE  TNA
Sbjct: 43 KVEEEHTNA 51
>NP_065811
          Length = 1572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1563 VEETST 1568
>NP_060899
          Length = 2624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_006725524
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_006725523
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_005276828
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_006726279
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_005262461
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QVEETS 6
           QVEETS
Sbjct: 354 QVEETS 359
>XP_006723795
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 117 LDETSSNA 124
>XP_006723794
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 127 LDETSSNA 134
>XP_006723793
          Length = 1513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 99  LDETSSNA 106
>XP_006723792
          Length = 1513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 99  LDETSSNA 106
>XP_006723791
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 117 LDETSSNA 124
>XP_006723790
          Length = 1540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VEETSTNA 9
           ++ETS+NA
Sbjct: 126 LDETSSNA 133
>XP_006716430
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QVEETSTNA 9
           Q E+T+TN+
Sbjct: 528 QEEDTATNS 536
>XP_005273626
          Length = 1190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QVEETSTNA 9
           Q E+T+TN+
Sbjct: 528 QEEDTATNS 536
>XP_006715736
          Length = 1573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1564 VEETST 1569
>XP_006715735
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1597 VEETST 1602
>XP_005249722
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1598 VEETST 1603
>XP_006715734
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1598 VEETST 1603
>XP_006715733
          Length = 1608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1599 VEETST 1604
>XP_006715608
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QVEETS 6
          QVEETS
Sbjct: 12 QVEETS 17
>XP_005248815
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QVEETS 6
          QVEETS
Sbjct: 12 QVEETS 17
>XP_006714722
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_006714721
          Length = 2623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    QVEETSTN 8
            ++EETST+
Sbjct: 1322 ELEETSTS 1329
>XP_006712712
          Length = 1414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1405 VEETST 1410
>XP_006712711
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1439 VEETST 1444
>XP_006712710
          Length = 1528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1519 VEETST 1524
>XP_006712709
          Length = 1579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    VEETST 7
            VEETST
Sbjct: 1570 VEETST 1575
>NP_001156752
          Length = 755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QVEETS 6
           QVEETS
Sbjct: 354 QVEETS 359
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.274   0.0915    0.200 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 473,771
Number of extensions: 504
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)

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