Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              20     509
NP_005913                                                              20     509
XP_005267046                                                           20     509
XP_005267045                                                           20     509
NP_055723                                                              16    5631
NP_068761                                                              16    5631
NP_951008                                                              16    5631
NP_055907                                                              16    7355
XP_005255242                                                           16    7355
XP_005255241                                                           16    7355
XP_005255240                                                           16    7355
XP_005255239                                                           16    7355
NP_000563                                                              15    9605
NP_002949                                                              15    9605
NP_001161076                                                           15    9605
NP_065116                                                              15    9605
NP_001073918                                                           15    9605
XP_006718026                                                           15    9605
XP_005270202                                                           15    9605
XP_006718025                                                           15    9605
XP_005270201                                                           15    9605
XP_006717743                                                           15    9605
NP_001005861                                                           15    9605
>NP_006715
          Length = 1558

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           QVDN+LLVV
Sbjct: 941 QVDNLLLVV 949
>NP_005913
          Length = 1608

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           QVDN+LLVV
Sbjct: 941 QVDNLLLVV 949
>XP_005267046
          Length = 1554

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           QVDN+LLVV
Sbjct: 941 QVDNLLLVV 949
>XP_005267045
          Length = 1604

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           QVDN+LLVV
Sbjct: 941 QVDNLLLVV 949
>NP_055723
          Length = 538

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QVDNILL 7
           Q+DN+LL
Sbjct: 522 QIDNLLL 528
>NP_068761
          Length = 1133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QVDNILL 7
           QVDN++L
Sbjct: 947 QVDNVIL 953
>NP_951008
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   QVDNILL 7
           QVDN++L
Sbjct: 947 QVDNVIL 953
>NP_055907
          Length = 3661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QVDNILLVV 9
           Q+DNIL  V
Sbjct: 188 QLDNILAAV 196
>XP_005255242
          Length = 3609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QVDNILLVV 9
           Q+DNIL  V
Sbjct: 136 QLDNILAAV 144
>XP_005255241
          Length = 3637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QVDNILLVV 9
           Q+DNIL  V
Sbjct: 136 QLDNILAAV 144
>XP_005255240
          Length = 3663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QVDNILLVV 9
           Q+DNIL  V
Sbjct: 162 QLDNILAAV 170
>XP_005255239
          Length = 3689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QVDNILLVV 9
           Q+DNIL  V
Sbjct: 188 QLDNILAAV 196
>NP_000563
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QVDNILL 7
          Q+DN+LL
Sbjct: 60 QLDNLLL 66
>NP_002949
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QVDNIL 6
           QVDN+L
Sbjct: 126 QVDNVL 131
>NP_001161076
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           +++N++LVV
Sbjct: 554 RIENVVLVV 562
>NP_065116
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           +++N++LVV
Sbjct: 578 RIENVVLVV 586
>NP_001073918
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDNILL 7
           VDNILL
Sbjct: 682 VDNILL 687
>XP_006718026
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           +++N++LVV
Sbjct: 464 RIENVVLVV 472
>XP_005270202
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           +++N++LVV
Sbjct: 530 RIENVVLVV 538
>XP_006718025
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           +++N++LVV
Sbjct: 578 RIENVVLVV 586
>XP_005270201
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   QVDNILLVV 9
           +++N++LVV
Sbjct: 574 RIENVVLVV 582
>XP_006717743
          Length = 1090

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VDNILL 7
           VDNILL
Sbjct: 712 VDNILL 717
>NP_001005861
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QVDNIL 6
           QVDN+L
Sbjct: 126 QVDNVL 131
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.151    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 393,723
Number of extensions: 519
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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