Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              19     665
XP_005273257                                                           19     665
NP_525022                                                              18    1935
NP_079029                                                              18    1935
NP_510880                                                              18    1935
NP_976063                                                              18    1935
XP_005256994                                                           18    1935
XP_006721697                                                           18    1935
XP_006721696                                                           18    1935
XP_005256991                                                           18    1935
XP_006712824                                                           18    1935
NP_065891                                                              17    4312
XP_005263215                                                           17    4312
NP_004272                                                              16    5631
NP_036466                                                              16    5631
NP_115946                                                              16    5631
NP_001277255                                                           16    5631
NP_001277254                                                           16    5631
NP_065996                                                              16    5631
XP_005270344                                                           16    5631
XP_005270064                                                           16    5631
XP_005270063                                                           16    5631
XP_005270062                                                           16    5631
XP_005270061                                                           16    5631
XP_006714538                                                           16    5631
NP_079285                                                              16    7355
NP_004989                                                              16    7355
NP_002750                                                              16    7355
NP_001129124                                                           16    7355
NP_001129123                                                           16    7355
NP_036467                                                              16    7355
XP_005272534                                                           16    7355
XP_005272533                                                           16    7355
XP_005272532                                                           16    7355
XP_005256727                                                           16    7355
XP_005256725                                                           16    7355
XP_005256724                                                           16    7355
XP_006714118                                                           16    7355
NP_659477                                                              16    7355
NP_056536                                                              16    7355
NP_116287                                                              15    9605
NP_620311                                                              15    9605
NP_001185748                                                           15    9605
NP_001185749                                                           15    9605
NP_060857                                                              15    9605
NP_001164608                                                           15    9605
NP_001140171                                                           15    9605
NP_001140170                                                           15    9605
NP_055872                                                              15    9605
NP_057280                                                              15    9605
NP_001035847                                                           15    9605
NP_005125                                                              15    9605
NP_001129980                                                           15    9605
XP_006719852                                                           15    9605
XP_005266357                                                           15    9605
XP_006719851                                                           15    9605
XP_006719850                                                           15    9605
XP_006719849                                                           15    9605
XP_006719848                                                           15    9605
XP_005266356                                                           15    9605
XP_006719847                                                           15    9605
XP_006719846                                                           15    9605
XP_006719845                                                           15    9605
XP_006719844                                                           15    9605
XP_006719843                                                           15    9605
XP_006719842                                                           15    9605
XP_006717872                                                           15    9605
XP_005252142                                                           15    9605
XP_005252140                                                           15    9605
XP_005269427                                                           15    9605
XP_005270828                                                           15    9605
NP_002163                                                              15    9605
>NP_064450
          Length = 1722

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QTLLEKLFS 9
           +TLLEKLFS
Sbjct: 540 RTLLEKLFS 548
>XP_005273257
          Length = 1726

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QTLLEKLFS 9
           +TLLEKLFS
Sbjct: 540 RTLLEKLFS 548
>NP_525022
          Length = 1624

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QTLLEKLFS 9
          QTLLE LFS
Sbjct: 29 QTLLEWLFS 37
>NP_079029
          Length = 1316

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           QTLLE+ FS
Sbjct: 310 QTLLERAFS 318
>NP_510880
          Length = 2054

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TLLEKLFS 9
           TLLE+LFS
Sbjct: 896 TLLERLFS 903
>NP_976063
          Length = 2039

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   TLLEKLFS 9
           TLLE+LFS
Sbjct: 896 TLLERLFS 903
>XP_005256994
          Length = 1443

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QTLLEKLFS 9
          QTLLE LFS
Sbjct: 37 QTLLEWLFS 45
>XP_006721697
          Length = 1625

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QTLLEKLFS 9
          QTLLE LFS
Sbjct: 37 QTLLEWLFS 45
>XP_006721696
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QTLLEKLFS 9
          QTLLE LFS
Sbjct: 37 QTLLEWLFS 45
>XP_005256991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QTLLEKLFS 9
          QTLLE LFS
Sbjct: 37 QTLLEWLFS 45
>XP_006712824
          Length = 1056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           QTLLE+ FS
Sbjct: 310 QTLLERAFS 318
>NP_065891
          Length = 1114

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  TLLEKLFS 9
          TLL+KLF+
Sbjct: 4  TLLQKLFN 11
>XP_005263215
          Length = 1144

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  TLLEKLFS 9
          TLL+KLF+
Sbjct: 4  TLLQKLFN 11
>NP_004272
          Length = 575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QT+LEKL
Sbjct: 488 QTILEKL 494
>NP_036466
          Length = 2058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TLLEKLFS 9
           TLLEKL S
Sbjct: 519 TLLEKLHS 526
>NP_115946
          Length = 1042

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QTLLEKLF 8
           +TL+EK+F
Sbjct: 583 KTLIEKMF 590
>NP_001277255
          Length = 587

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QTLLEKLF 8
           +TL+EK+F
Sbjct: 128 KTLIEKMF 135
>NP_001277254
          Length = 1004

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QTLLEKLF 8
           +TL+EK+F
Sbjct: 583 KTLIEKMF 590
>NP_065996
          Length = 3184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            Q L+EKL+S
Sbjct: 1966 QKLVEKLYS 1974
>XP_005270344
          Length = 574

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QT+LEKL
Sbjct: 487 QTILEKL 493
>XP_005270064
          Length = 1615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           Q L+EKL+S
Sbjct: 397 QKLVEKLYS 405
>XP_005270063
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            Q L+EKL+S
Sbjct: 1966 QKLVEKLYS 1974
>XP_005270062
          Length = 3184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            Q L+EKL+S
Sbjct: 1966 QKLVEKLYS 1974
>XP_005270061
          Length = 3184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            Q L+EKL+S
Sbjct: 1966 QKLVEKLYS 1974
>XP_006714538
          Length = 2035

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   TLLEKLFS 9
           TLLEKL S
Sbjct: 519 TLLEKLHS 526
>NP_079285
          Length = 1140

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLEKLFS 9
          L+EKLFS
Sbjct: 32 LVEKLFS 38
>NP_004989
          Length = 1108

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QTLL+KL
Sbjct: 479 QTLLQKL 485
>NP_002750
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           +TLL+KL S
Sbjct: 512 KTLLQKLLS 520
>NP_001129124
          Length = 510

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           +TLL+KL S
Sbjct: 471 KTLLQKLLS 479
>NP_001129123
          Length = 551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           +TLL+KL S
Sbjct: 512 KTLLQKLLS 520
>NP_036467
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QTLL+KL
Sbjct: 477 QTLLQKL 483
>XP_005272534
          Length = 1071

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QTLL+KL
Sbjct: 450 QTLLQKL 456
>XP_005272533
          Length = 1096

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QTLL+KL
Sbjct: 475 QTLLQKL 481
>XP_005272532
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QTLLEKL 7
           QTLL+KL
Sbjct: 479 QTLLQKL 485
>XP_005256727
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            QTLL+K+ S
Sbjct: 1038 QTLLQKMSS 1046
>XP_005256725
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            QTLL+K+ S
Sbjct: 1053 QTLLQKMSS 1061
>XP_005256724
          Length = 1062

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            QTLL+K+ S
Sbjct: 1053 QTLLQKMSS 1061
>XP_006714118
          Length = 1129

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LLEKLFS 9
          L+EKLFS
Sbjct: 32 LVEKLFS 38
>NP_659477
          Length = 261

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TLLEKLFS 9
          TLLEKL S
Sbjct: 27 TLLEKLAS 34
>NP_056536
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QTLLEKLFS 9
            QTLL+K+ S
Sbjct: 1049 QTLLQKMSS 1057
>NP_116287
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LEKLFS 9
          LEKLFS
Sbjct: 74 LEKLFS 79
>NP_620311
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QTLLEK 6
          QTLLEK
Sbjct: 36 QTLLEK 41
>NP_001185748
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QTLLEK 6
          QTLLEK
Sbjct: 36 QTLLEK 41
>NP_001185749
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QTLLEK 6
          QTLLEK
Sbjct: 36 QTLLEK 41
>NP_060857
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 571 LEKLFS 576
>NP_001164608
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 557 LEKLFS 562
>NP_001140171
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 418 LEKLFS 423
>NP_001140170
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 418 LEKLFS 423
>NP_055872
          Length = 4678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4038 TLLQDLFS 4045
>NP_057280
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 418 LEKLFS 423
>NP_001035847
          Length = 950

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTLLEK 6
           QTLLEK
Sbjct: 891 QTLLEK 896
>NP_005125
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTLLEK 6
           QTLLEK
Sbjct: 874 QTLLEK 879
>NP_001129980
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           + L+EK+FS
Sbjct: 172 EPLMEKVFS 180
>XP_006719852
          Length = 4752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4112 TLLQDLFS 4119
>XP_005266357
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 3960 TLLQDLFS 3967
>XP_006719851
          Length = 4689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4049 TLLQDLFS 4056
>XP_006719850
          Length = 4697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4057 TLLQDLFS 4064
>XP_006719849
          Length = 4703

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4063 TLLQDLFS 4070
>XP_006719848
          Length = 4737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4097 TLLQDLFS 4104
>XP_005266356
          Length = 4755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4115 TLLQDLFS 4122
>XP_006719847
          Length = 4761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4121 TLLQDLFS 4128
>XP_006719846
          Length = 4763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4123 TLLQDLFS 4130
>XP_006719845
          Length = 4772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4132 TLLQDLFS 4139
>XP_006719844
          Length = 4789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4149 TLLQDLFS 4156
>XP_006719843
          Length = 4794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4154 TLLQDLFS 4161
>XP_006719842
          Length = 4797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TLLEKLFS 9
            TLL+ LFS
Sbjct: 4157 TLLQDLFS 4164
>XP_006717872
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QTLLEK 6
          QTLLEK
Sbjct: 36 QTLLEK 41
>XP_005252142
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 518 LEKLFS 523
>XP_005252140
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LEKLFS 9
           LEKLFS
Sbjct: 571 LEKLFS 576
>XP_005269427
          Length = 167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LEKLFS 9
          LEKLFS
Sbjct: 74 LEKLFS 79
>XP_005270828
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QTLLEKLFS 9
           + L+EK+FS
Sbjct: 417 EPLMEKVFS 425
>NP_002163
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTLLEKLF 8
           +TLLEK +
Sbjct: 102 ETLLEKFY 109
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.135    0.328 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,814
Number of extensions: 1044
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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