Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     665
NP_005913                                                              19     665
XP_005267046                                                           19     665
XP_005267045                                                           19     665
XP_005272221                                                           17    3301
NP_061829                                                              17    3301
NP_003283                                                              16    5631
NP_001271230                                                           16    5631
NP_001271231                                                           16    5631
NP_061155                                                              16    5631
XP_006715810                                                           16    5631
XP_006715809                                                           16    5631
XP_005245528                                                           16    5631
NP_003631                                                              16    7355
NP_892006                                                              16    7355
NP_149062                                                              16    7355
NP_005637                                                              16    7355
NP_060838                                                              16    7355
XP_005252342                                                           16    7355
XP_006715574                                                           16    7355
XP_006715488                                                           16    7355
XP_006715487                                                           16    7355
XP_006715486                                                           16    7355
XP_006715485                                                           16    7355
XP_006715484                                                           16    7355
XP_006715483                                                           16    7355
XP_006715482                                                           16    7355
XP_006715481                                                           16    7355
XP_006715480                                                           16    7355
XP_006715479                                                           16    7355
XP_006715478                                                           16    7355
XP_006715477                                                           16    7355
XP_006715476                                                           16    7355
XP_006715475                                                           16    7355
XP_006715474                                                           16    7355
XP_006715473                                                           16    7355
XP_006715472                                                           16    7355
XP_006715471                                                           16    7355
XP_006715470                                                           16    7355
XP_005273291                                                           16    7355
NP_001106849                                                           15    9605
NP_060663                                                              15    9605
NP_057226                                                              15    9605
>NP_006715
          Length = 1558

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTLISQSKD 9
            +TLISQSKD
Sbjct: 1228 RTLISQSKD 1236
>NP_005913
          Length = 1608

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTLISQSKD 9
            +TLISQSKD
Sbjct: 1278 RTLISQSKD 1286
>XP_005267046
          Length = 1554

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTLISQSKD 9
            +TLISQSKD
Sbjct: 1224 RTLISQSKD 1232
>XP_005267045
          Length = 1604

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTLISQSKD 9
            +TLISQSKD
Sbjct: 1274 RTLISQSKD 1282
>XP_005272221
          Length = 222

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLISQSKD 9
           +TL+SQS D
Sbjct: 101 KTLVSQSND 109
>NP_061829
          Length = 168

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLISQSKD 9
           +TL+SQS D
Sbjct: 101 KTLVSQSND 109
>NP_003283
          Length = 2363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QTLISQSKD 9
            Q L+SQ KD
Sbjct: 1340 QHLVSQQKD 1348
>NP_001271230
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            +TL+SQ +D
Sbjct: 1033 ETLVSQCRD 1041
>NP_001271231
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            +TL+SQ +D
Sbjct: 1032 ETLVSQCRD 1040
>NP_061155
          Length = 1124

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            +TL+SQ +D
Sbjct: 1070 ETLVSQCRD 1078
>XP_006715810
          Length = 1105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            +TL+SQ +D
Sbjct: 1051 ETLVSQCRD 1059
>XP_006715809
          Length = 1142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            +TL+SQ +D
Sbjct: 1088 ETLVSQCRD 1096
>XP_005245528
          Length = 2439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QTLISQSKD 9
            Q L+SQ KD
Sbjct: 1416 QHLVSQQKD 1424
>NP_003631
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QTLISQSKD 9
           QTLI  +KD
Sbjct: 131 QTLIMMTKD 139
>NP_892006
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5570 QTLLEESKE 5578
>NP_149062
          Length = 8749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5499 QTLLEESKE 5507
>NP_005637
          Length = 1621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QTLISQSKD 9
          + L+SQS+D
Sbjct: 7  EALLSQSRD 15
>NP_060838
          Length = 540

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTLISQSKD 9
           QT+ S+SKD
Sbjct: 249 QTIKSKSKD 257
>XP_005252342
          Length = 1218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  QTLISQSKD 9
          QTLI  +KD
Sbjct: 17 QTLIMMTKD 25
>XP_006715574
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  QTLISQSKD 9
          QT+ S+SKD
Sbjct: 45 QTIKSKSKD 53
>XP_006715488
          Length = 8721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715487
          Length = 8744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715486
          Length = 8758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715485
          Length = 8793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5524 QTLLEESKE 5532
>XP_006715484
          Length = 8794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5525 QTLLEESKE 5533
>XP_006715483
          Length = 8795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715482
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5570 QTLLEESKE 5578
>XP_006715481
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5530 QTLLEESKE 5538
>XP_006715480
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715479
          Length = 8804

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715478
          Length = 8809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715477
          Length = 8822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5553 QTLLEESKE 5561
>XP_006715476
          Length = 8823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715475
          Length = 8827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715474
          Length = 8829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5560 QTLLEESKE 5568
>XP_006715473
          Length = 8832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715472
          Length = 8839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5570 QTLLEESKE 5578
>XP_006715471
          Length = 8842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_006715470
          Length = 8846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QTLISQSKD 9
            QTL+ +SK+
Sbjct: 5577 QTLLEESKE 5585
>XP_005273291
          Length = 1620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QTLISQSKD 9
          + L+SQS+D
Sbjct: 7  EALLSQSRD 15
>NP_001106849
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QTLISQSK 8
           QTL+SQ K
Sbjct: 625 QTLLSQLK 632
>NP_060663
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QTLISQSK 8
           QTL+SQ K
Sbjct: 625 QTLLSQLK 632
>NP_057226
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LISQSKD 9
          LIS+SKD
Sbjct: 79 LISRSKD 85
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.111    0.253 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 367,386
Number of extensions: 635
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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