Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              20     509
NP_444254                                                              20     509
NP_444253                                                              20     509
NP_444255                                                              20     509
XP_005247551                                                           20     509
XP_005247550                                                           20     509
XP_006713712                                                           20     509
XP_005247549                                                           20     509
NP_872299                                                              16    5631
NP_001138617                                                           16    5631
NP_005619                                                              16    5631
XP_005259224                                                           16    5631
XP_005256292                                                           16    5631
XP_006721397                                                           16    5631
XP_005256291                                                           16    5631
XP_005256290                                                           16    5631
XP_006721396                                                           16    5631
XP_005253105                                                           16    5631
NP_976221                                                              16    7355
NP_001230829                                                           16    7355
NP_005327                                                              16    7355
NP_001035526                                                           16    7355
NP_291027                                                              16    7355
NP_775871                                                              16    7355
XP_005253438                                                           16    7355
XP_006712539                                                           16    7355
XP_005247059                                                           16    7355
XP_005247058                                                           16    7355
XP_006712538                                                           16    7355
XP_005247060                                                           16    7355
XP_005247057                                                           16    7355
NP_478055                                                              15    9605
NP_001026851                                                           15    9605
NP_004928                                                              15    9605
NP_478054                                                              15    9605
NP_001840                                                              15    9605
NP_001278062                                                           15    9605
NP_127493                                                              15    9605
NP_127494                                                              15    9605
NP_001157108                                                           15    9605
NP_001509                                                              15    9605
NP_127492                                                              15    9605
NP_853553                                                              15    9605
NP_003820                                                              15    9605
NP_001248335                                                           15    9605
NP_001248336                                                           15    9605
NP_054907                                                              15    9605
XP_006721526                                                           15    9605
XP_005256542                                                           15    9605
XP_006716955                                                           15    9605
XP_005251680                                                           15    9605
XP_006716954                                                           15    9605
XP_006716953                                                           15    9605
XP_006716952                                                           15    9605
XP_006716951                                                           15    9605
XP_006716950                                                           15    9605
XP_006716949                                                           15    9605
XP_006716948                                                           15    9605
XP_005251679                                                           15    9605
XP_006716009                                                           15    9605
XP_005250353                                                           15    9605
XP_006716008                                                           15    9605
XP_006716007                                                           15    9605
XP_006716006                                                           15    9605
XP_006716005                                                           15    9605
XP_006716004                                                           15    9605
XP_006716003                                                           15    9605
XP_006716002                                                           15    9605
XP_005250348                                                           15    9605
XP_005264449                                                           15    9605
>NP_444256
          Length = 1794

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1527 KTGTRIKLI 1535
>NP_444254
          Length = 1845

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1527 KTGTRIKLI 1535
>NP_444253
          Length = 1914

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1596 KTGTRIKLI 1604
>NP_444255
          Length = 1863

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1596 KTGTRIKLI 1604
>XP_005247551
          Length = 1855

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1537 KTGTRIKLI 1545
>XP_005247550
          Length = 1856

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1538 KTGTRIKLI 1546
>XP_006713712
          Length = 1923

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1606 KTGTRIKLI 1614
>XP_005247549
          Length = 1924

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QTGTRIKLI 9
            +TGTRIKLI
Sbjct: 1606 KTGTRIKLI 1614
>NP_872299
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           QTG +IK+I
Sbjct: 647 QTGHQIKII 655
>NP_001138617
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TGTRIKL 8
          TGTR+K+
Sbjct: 12 TGTRVKV 18
>NP_005619
          Length = 541

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TGTRIKL 8
           TGTR+K+
Sbjct: 214 TGTRVKV 220
>XP_005259224
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TGTRIKL 8
           TGTR+K+
Sbjct: 214 TGTRVKV 220
>XP_005256292
          Length = 478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           QTG +IK+I
Sbjct: 306 QTGHQIKII 314
>XP_006721397
          Length = 478

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           QTG +IK+I
Sbjct: 306 QTGHQIKII 314
>XP_005256291
          Length = 678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           QTG +IK+I
Sbjct: 506 QTGHQIKII 514
>XP_005256290
          Length = 689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           QTG +IK+I
Sbjct: 517 QTGHQIKII 525
>XP_006721396
          Length = 819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           QTG +IK+I
Sbjct: 647 QTGHQIKII 655
>XP_005253105
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  QTGTRIK 7
          +TGTR+K
Sbjct: 10 RTGTRVK 16
>NP_976221
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>NP_001230829
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 287 ETGTRINI 294
>NP_005327
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>NP_001035526
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QTGTRIKL 8
          +TGT+I+L
Sbjct: 54 ETGTKIEL 61
>NP_291027
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GTRIKL 8
           GTRIKL
Sbjct: 623 GTRIKL 628
>NP_775871
          Length = 8384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TGTRIKLI 9
            TG +IKL+
Sbjct: 7118 TGAKIKLV 7125
>XP_005253438
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QTGTRIKL 8
          +TGT+I+L
Sbjct: 54 ETGTKIEL 61
>XP_006712539
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>XP_005247059
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>XP_005247058
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>XP_006712538
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>XP_005247060
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>XP_005247057
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGTRIKL 8
           +TGTRI +
Sbjct: 251 ETGTRINI 258
>NP_478055
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           +TGTR+ ++
Sbjct: 655 ETGTRVGVV 663
>NP_001026851
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           QTG RI+ +
Sbjct: 108 QTGPRIRFL 116
>NP_004928
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           QTG RI+ +
Sbjct: 108 QTGPRIRFL 116
>NP_478054
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           +TGTR+ ++
Sbjct: 655 ETGTRVGVV 663
>NP_001840
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QTGTRIKLI 9
           +TGTR+ ++
Sbjct: 655 ETGTRVGVV 663
>NP_001278062
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TGTRIKLI 9
           TG +IKL+
Sbjct: 372 TGVKIKLL 379
>NP_127493
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 509 QVGNRIKFV 517
>NP_127494
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 508 QVGNRIKFV 516
>NP_001157108
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 507 QVGNRIKFV 515
>NP_001509
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 488 QVGNRIKFV 496
>NP_127492
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 529 QVGNRIKFV 537
>NP_853553
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QTGTRI 6
           QTGTR+
Sbjct: 254 QTGTRL 259
>NP_003820
          Length = 2041

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>NP_001248335
          Length = 2037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>NP_001248336
          Length = 2008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>NP_054907
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  TGTRIKL 8
          TGT +KL
Sbjct: 38 TGTHVKL 44
>XP_006721526
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           QTG RI+ +
Sbjct: 108 QTGPRIRFL 116
>XP_005256542
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           QTG RI+ +
Sbjct: 108 QTGPRIRFL 116
>XP_006716955
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_005251680
          Length = 2000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716954
          Length = 2008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716953
          Length = 2031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716952
          Length = 2037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716951
          Length = 2041

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716950
          Length = 2070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716949
          Length = 2070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716948
          Length = 2070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_005251679
          Length = 2070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTGTRIKLI 9
           Q G R+KL+
Sbjct: 324 QCGNRVKLM 332
>XP_006716009
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 541 QVGNRIKFV 549
>XP_005250353
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 500 QVGNRIKFV 508
>XP_006716008
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 519 QVGNRIKFV 527
>XP_006716007
          Length = 989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 520 QVGNRIKFV 528
>XP_006716006
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 521 QVGNRIKFV 529
>XP_006716005
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 529 QVGNRIKFV 537
>XP_006716004
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 534 QVGNRIKFV 542
>XP_006716003
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 540 QVGNRIKFV 548
>XP_006716002
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 541 QVGNRIKFV 549
>XP_005250348
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   QTGTRIKLI 9
           Q G RIK +
Sbjct: 541 QVGNRIKFV 549
>XP_005264449
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QTGTRI 6
           QTGTR+
Sbjct: 311 QTGTRL 316
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.141    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 471,193
Number of extensions: 681
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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