Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     509
NP_001161879                                                           17    4312
NP_055804                                                              17    4312
NP_919269                                                              17    4312
XP_006715455                                                           17    4312
XP_006715452                                                           17    4312
XP_006715451                                                           17    4312
XP_006715450                                                           17    4312
XP_005248745                                                           17    4312
XP_005248744                                                           17    4312
XP_005248743                                                           17    4312
XP_005248742                                                           17    4312
XP_006715449                                                           17    4312
XP_006715448                                                           17    4312
XP_006715447                                                           17    4312
XP_006715446                                                           17    4312
XP_005264966                                                           17    4312
XP_006710433                                                           16    5631
XP_006710432                                                           16    5631
XP_006710431                                                           16    5631
XP_006710430                                                           16    5631
XP_006710429                                                           16    5631
NP_001009811                                                           16    7355
NP_055799                                                              16    7355
NP_001277251                                                           16    7355
NP_005500                                                              16    7355
NP_001277250                                                           16    7355
NP_689870                                                              16    7355
NP_005928                                                              16    7355
NP_068591                                                              16    7355
NP_060529                                                              16    7355
NP_001129509                                                           16    7355
XP_006725391                                                           16    7355
XP_006725390                                                           16    7355
XP_006725389                                                           16    7355
XP_006725388                                                           16    7355
XP_006725387                                                           16    7355
XP_005258676                                                           16    7355
XP_005257438                                                           16    7355
XP_005257437                                                           16    7355
XP_006721974                                                           16    7355
XP_006721973                                                           16    7355
XP_005257436                                                           16    7355
XP_005257233                                                           16    7355
XP_005257231                                                           16    7355
XP_005271970                                                           16    7355
XP_005271969                                                           16    7355
XP_005271967                                                           16    7355
XP_005271966                                                           16    7355
NP_114096                                                              16    7355
NP_004200                                                              15    9605
NP_003681                                                              15    9605
NP_001132990                                                           15    9605
NP_001132989                                                           15    9605
NP_937870                                                              15    9605
NP_937872                                                              15    9605
XP_006715629                                                           15    9605
XP_006713970                                                           15    9605
XP_006713968                                                           15    9605
XP_005246978                                                           15    9605
NP_078970                                                              15    9605
>NP_115803
          Length = 1156

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   QTGSGASQA 9
           QTGSGAS+A
Sbjct: 415 QTGSGASRA 423
>NP_001161879
          Length = 1012

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TGSGASQ 8
           TGSG+SQ
Sbjct: 626 TGSGSSQ 632
>NP_055804
          Length = 1692

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1306 TGSGSSQ 1312
>NP_919269
          Length = 1843

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QTGSGASQ 8
            QTG G+SQ
Sbjct: 1753 QTGPGSSQ 1760
>XP_006715455
          Length = 474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  TGSGASQ 8
          TGSG+SQ
Sbjct: 88 TGSGSSQ 94
>XP_006715452
          Length = 1474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1088 TGSGSSQ 1094
>XP_006715451
          Length = 1475

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1098 TGSGSSQ 1104
>XP_006715450
          Length = 1498

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1112 TGSGSSQ 1118
>XP_005248745
          Length = 1515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1129 TGSGSSQ 1135
>XP_005248744
          Length = 1519

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1133 TGSGSSQ 1139
>XP_005248743
          Length = 1525

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1139 TGSGSSQ 1145
>XP_005248742
          Length = 1535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1149 TGSGSSQ 1155
>XP_006715449
          Length = 1539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1153 TGSGSSQ 1159
>XP_006715448
          Length = 1549

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1163 TGSGSSQ 1169
>XP_006715447
          Length = 1574

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1188 TGSGSSQ 1194
>XP_006715446
          Length = 1574

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    TGSGASQ 8
            TGSG+SQ
Sbjct: 1188 TGSGSSQ 1194
>XP_005264966
          Length = 1843

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QTGSGASQ 8
            QTG G+SQ
Sbjct: 1753 QTGPGSSQ 1760
>XP_006710433
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TGSGASQ 8
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710432
          Length = 1202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TGSGASQ 8
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710431
          Length = 1205

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TGSGASQ 8
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710430
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TGSGASQ 8
           TGSGAS+
Sbjct: 277 TGSGASR 283
>XP_006710429
          Length = 1238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TGSGASQ 8
           TGSGAS+
Sbjct: 277 TGSGASR 283
>NP_001009811
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TGSGASQA 9
          TG G SQA
Sbjct: 62 TGPGGSQA 69
>NP_055799
          Length = 1080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TGSGASQA 9
          TG G SQA
Sbjct: 62 TGPGGSQA 69
>NP_001277251
          Length = 2854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2558 QTGRGAS 2564
>NP_005500
          Length = 3027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2731 QTGRGAS 2737
>NP_001277250
          Length = 3048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2752 QTGRGAS 2758
>NP_689870
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSGASQ 8
           GSGASQ
Sbjct: 566 GSGASQ 571
>NP_005928
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 433 TGSGAS 438
>NP_068591
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   QTGSGASQ 8
           Q G GASQ
Sbjct: 164 QPGDGASQ 171
>NP_060529
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSGASQ 8
           GSGASQ
Sbjct: 823 GSGASQ 828
>NP_001129509
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  TGSGASQA 9
          TGSGA+ A
Sbjct: 13 TGSGAAPA 20
>XP_006725391
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_006725390
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 344 TGSGAS 349
>XP_006725389
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 407 TGSGAS 412
>XP_006725388
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 434 TGSGAS 439
>XP_006725387
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_005258676
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   GSGASQ 8
           GSGASQ
Sbjct: 566 GSGASQ 571
>XP_005257438
          Length = 992

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_005257437
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 344 TGSGAS 349
>XP_006721974
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 407 TGSGAS 412
>XP_006721973
          Length = 1094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 434 TGSGAS 439
>XP_005257436
          Length = 1120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 460 TGSGAS 465
>XP_005257233
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TGSGASQA 9
          TG G SQA
Sbjct: 62 TGPGGSQA 69
>XP_005257231
          Length = 1080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  TGSGASQA 9
          TG G SQA
Sbjct: 62 TGPGGSQA 69
>XP_005271970
          Length = 2931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2790 QTGRGAS 2796
>XP_005271969
          Length = 3020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2724 QTGRGAS 2730
>XP_005271967
          Length = 3065

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2769 QTGRGAS 2775
>XP_005271966
          Length = 3086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    QTGSGAS 7
            QTG GAS
Sbjct: 2790 QTGRGAS 2796
>NP_114096
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TGSGAS 7
           TGSGAS
Sbjct: 162 TGSGAS 167
>NP_004200
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QTGSGASQA 9
           Q  +GASQA
Sbjct: 184 QLSTGASQA 192
>NP_003681
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGSGASQ 8
           +TG GAS+
Sbjct: 170 ETGKGASK 177
>NP_001132990
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGSGASQ 8
           +TG GAS+
Sbjct: 145 ETGKGASK 152
>NP_001132989
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QTGSGASQ 8
           +TG GAS+
Sbjct: 159 ETGKGASK 166
>NP_937870
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QTGSGASQA 9
           Q G G SQA
Sbjct: 759 QAGPGRSQA 767
>NP_937872
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    QTGSGASQA 9
            Q G G SQA
Sbjct: 1407 QAGPGRSQA 1415
>XP_006715629
          Length = 1667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QTGSGAS 7
            QTGSG++
Sbjct: 1464 QTGSGSA 1470
>XP_006713970
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   QTGSGASQA 9
           Q G G SQA
Sbjct: 606 QAGPGRSQA 614
>XP_006713968
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    QTGSGASQA 9
            Q G G SQA
Sbjct: 1407 QAGPGRSQA 1415
>XP_005246978
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  QTGSGASQ 8
          +TG GAS+
Sbjct: 57 ETGKGASK 64
>NP_078970
          Length = 1667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    QTGSGAS 7
            QTGSG++
Sbjct: 1464 QTGSGSA 1470
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.285   0.0997    0.243 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 633,742
Number of extensions: 676
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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