Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
NP_115664                                                              16    5631
NP_001011537                                                           16    5631
NP_065194                                                              16    7355
NP_003904                                                              16    7355
XP_006715301                                                           16    7355
NP_116103                                                              15    9605
NP_071934                                                              15    9605
NP_001026884                                                           15    9605
NP_071926                                                              15    9605
NP_066013                                                              15    9605
NP_001012303                                                           15    9605
NP_006208                                                              15    9605
XP_006720685                                                           15    9605
XP_005268062                                                           15    9605
XP_005268061                                                           15    9605
XP_006714856                                                           15    9605
XP_005268556                                                           15    9605
XP_006714855                                                           15    9605
XP_006714854                                                           15    9605
XP_005268555                                                           15    9605
XP_005268554                                                           15    9605



>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QTGMTLIL 8
           QTGMTLIL
Sbjct: 426 QTGMTLIL 433





>NP_115664
          Length = 318

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTGMTL 6
           QTGMTL
Sbjct: 286 QTGMTL 291





>NP_001011537
          Length = 292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTGMTL 6
           QTGMTL
Sbjct: 260 QTGMTL 265





>NP_065194
          Length = 1819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QTGMTLILE 9
           QTGM  +LE
Sbjct: 911 QTGMVPLLE 919





>NP_003904
          Length = 1007

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGMTLILE 9
           Q+GM LIL+
Sbjct: 130 QSGMGLILQ 138





>XP_006715301
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QTGMTLILE 9
           Q+GM LIL+
Sbjct: 130 QSGMGLILQ 138





>NP_116103
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QTGMTLILE 9
          Q+G+ L+LE
Sbjct: 71 QSGLDLLLE 79





>NP_071934
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QTGMTLILE 9
          Q+G+ L+LE
Sbjct: 71 QSGLDLLLE 79





>NP_001026884
          Length = 1240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QTGMTLILE 9
          Q+G+ L+LE
Sbjct: 71 QSGLDLLLE 79





>NP_071926
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1293 GFTLILE 1299





>NP_066013
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    TGMTLILE 9
            TG TL+L+
Sbjct: 1099 TGQTLLLQ 1106





>NP_001012303
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GMTLILE 9
          G+TL+LE
Sbjct: 61 GITLVLE 67





>NP_006208
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  GMTLILE 9
          G+TL+LE
Sbjct: 51 GITLVLE 57





>XP_006720685
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TGMTLILE 9
           TG TL+L+
Sbjct: 514 TGQTLLLQ 521





>XP_005268062
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QTGMTLILE 9
           Q+G+ L+LE
Sbjct: 103 QSGLDLLLE 111





>XP_005268061
          Length = 1281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QTGMTLILE 9
           Q+G+ L+LE
Sbjct: 103 QSGLDLLLE 111





>XP_006714856
          Length = 1346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1095 GFTLILE 1101





>XP_005268556
          Length = 1466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1215 GFTLILE 1221





>XP_006714855
          Length = 1473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1222 GFTLILE 1228





>XP_006714854
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1235 GFTLILE 1241





>XP_005268555
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1273 GFTLILE 1279





>XP_005268554
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    GMTLILE 9
            G TLILE
Sbjct: 1293 GFTLILE 1299





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.135    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 437,222
Number of extensions: 580
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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