Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_116205                                                              17    2528
XP_005259403                                                           17    2528
XP_005259401                                                           17    2528
NP_055523                                                              16    5631
NP_060356                                                              16    5631
XP_006719769                                                           16    5631
XP_005265319                                                           16    5631
XP_006713278                                                           16    5631
XP_005265318                                                           16    5631
NP_056448                                                              16    7355
NP_001165358                                                           16    7355
NP_055999                                                              16    7355
NP_001137854                                                           16    7355
NP_848639                                                              16    7355
NP_001768                                                              16    7355
NP_942088                                                              16    7355
XP_005258911                                                           16    7355
XP_005258910                                                           16    7355
XP_005247966                                                           16    7355
XP_005247965                                                           16    7355
XP_006713136                                                           16    7355
NP_001003712                                                           15    9605
NP_065892                                                              15    9605
NP_055912                                                              15    9605
NP_001268675                                                           15    9605
NP_001193973                                                           15    9605
NP_001268676                                                           15    9605
XP_005268680                                                           15    9605
XP_006719287                                                           15    9605
XP_005268679                                                           15    9605
XP_005268678                                                           15    9605
XP_006719286                                                           15    9605
XP_006719285                                                           15    9605
XP_006715311                                                           15    9605
XP_006715310                                                           15    9605
XP_005249535                                                           15    9605
XP_006715309                                                           15    9605
XP_005249534                                                           15    9605
XP_006715308                                                           15    9605
XP_006715307                                                           15    9605
XP_005249533                                                           15    9605
XP_006713123                                                           15    9605
XP_006713122                                                           15    9605
XP_006713121                                                           15    9605
XP_006713120                                                           15    9605
XP_006713119                                                           15    9605
XP_006713118                                                           15    9605
XP_006713117                                                           15    9605
XP_006713116                                                           15    9605
XP_006713115                                                           15    9605
XP_006713114                                                           15    9605
XP_006713113                                                           15    9605
XP_006713112                                                           15    9605
XP_006713111                                                           15    9605
XP_006713110                                                           15    9605
XP_006713109                                                           15    9605
XP_006713108                                                           15    9605
XP_006713107                                                           15    9605
XP_006713106                                                           15    9605
XP_006713105                                                           15    9605
XP_006713104                                                           15    9605
XP_006713103                                                           15    9605
XP_006713102                                                           15    9605
XP_006713101                                                           15    9605
XP_006713100                                                           15    9605
XP_006713099                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QTELTRESF 9
            QTEL RESF
Sbjct: 1875 QTELMRESF 1883
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QTELTRESF 9
            QTEL RESF
Sbjct: 1875 QTELMRESF 1883
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QTELTRESF 9
            QTEL RESF
Sbjct: 1828 QTELMRESF 1836
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QTELTRESF 9
            QTEL RESF
Sbjct: 1907 QTELMRESF 1915
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QTELTRESF 9
            QTEL RESF
Sbjct: 1907 QTELMRESF 1915
>NP_116205
          Length = 783

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TE+TRE F
Sbjct: 233 TEITREKF 240
>XP_005259403
          Length = 475

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TE+TRE F
Sbjct: 233 TEITREKF 240
>XP_005259401
          Length = 759

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TE+TRE F
Sbjct: 233 TEITREKF 240
>NP_055523
          Length = 2209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TELTRESF 9
            TEL+ ESF
Sbjct: 1610 TELSEESF 1617
>NP_060356
          Length = 1275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TEL RE+F
Sbjct: 558 TELIRENF 565
>XP_006719769
          Length = 2209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TELTRESF 9
            TEL+ ESF
Sbjct: 1610 TELSEESF 1617
>XP_005265319
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TEL RE+F
Sbjct: 558 TELIRENF 565
>XP_006713278
          Length = 1156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TEL RE+F
Sbjct: 439 TELIRENF 446
>XP_005265318
          Length = 1274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TEL RE+F
Sbjct: 557 TELIRENF 564
>NP_056448
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 219 QITRESF 225
>NP_001165358
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 181 QITRESF 187
>NP_055999
          Length = 1001

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TE+T+E F
Sbjct: 198 TEVTKEEF 205
>NP_001137854
          Length = 1127

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TE+T+E F
Sbjct: 324 TEVTKEEF 331
>NP_848639
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTELTR 6
           QTELTR
Sbjct: 453 QTELTR 458
>NP_001768
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TELTRE 7
           TELTRE
Sbjct: 117 TELTRE 122
>NP_942088
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TELTRE 7
           TELTRE
Sbjct: 117 TELTRE 122
>XP_005258911
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTELTR 6
           QTELTR
Sbjct: 415 QTELTR 420
>XP_005258910
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QTELTR 6
           QTELTR
Sbjct: 427 QTELTR 432
>XP_005247966
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TELTRE 7
           TELTRE
Sbjct: 117 TELTRE 122
>XP_005247965
          Length = 312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TELTRE 7
           TELTRE
Sbjct: 117 TELTRE 122
>XP_006713136
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TELTRESF 9
           TE+T+E F
Sbjct: 219 TEVTKEEF 226
>NP_001003712
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 657 QTEATQEKY 665
>NP_065892
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 699 QTEATQEKY 707
>NP_055912
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 983 DVTRESF 989
>NP_001268675
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 473 SELTQQSF 480
>NP_001193973
          Length = 1294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 762 DVTRESF 768
>NP_001268676
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 484 SELTQQSF 491
>XP_005268680
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 657 QTEATQEKY 665
>XP_006719287
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 657 QTEATQEKY 665
>XP_005268679
          Length = 886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 696 QTEATQEKY 704
>XP_005268678
          Length = 889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 699 QTEATQEKY 707
>XP_006719286
          Length = 909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 719 QTEATQEKY 727
>XP_006719285
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QTELTRESF 9
           QTE T+E +
Sbjct: 722 QTEATQEKY 730
>XP_006715311
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 355 SELTQQSF 362
>XP_006715310
          Length = 866

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 355 SELTQQSF 362
>XP_005249535
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 421 SELTQQSF 428
>XP_006715309
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 473 SELTQQSF 480
>XP_005249534
          Length = 974

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 463 SELTQQSF 470
>XP_006715308
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 467 SELTQQSF 474
>XP_006715307
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 473 SELTQQSF 480
>XP_005249533
          Length = 984

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TELTRESF 9
           +ELT++SF
Sbjct: 473 SELTQQSF 480
>XP_006713123
          Length = 1514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 982 DVTRESF 988
>XP_006713122
          Length = 1062

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1013 DVTRESF 1019
>XP_006713121
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 754 DVTRESF 760
>XP_006713120
          Length = 1287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 755 DVTRESF 761
>XP_006713119
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 776 DVTRESF 782
>XP_006713118
          Length = 1328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 779 DVTRESF 785
>XP_006713117
          Length = 1334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 785 DVTRESF 791
>XP_006713116
          Length = 1507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 975 DVTRESF 981
>XP_006713115
          Length = 1514

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 982 DVTRESF 988
>XP_006713114
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 991 DVTRESF 997
>XP_006713113
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 975 DVTRESF 981
>XP_006713112
          Length = 1527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 995  DVTRESF 1001
>XP_006713111
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 983 DVTRESF 989
>XP_006713110
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 984 DVTRESF 990
>XP_006713109
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1005 DVTRESF 1011
>XP_006713108
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ELTRESF 9
           ++TRESF
Sbjct: 992 DVTRESF 998
>XP_006713107
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1012 DVTRESF 1018
>XP_006713106
          Length = 1545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1013 DVTRESF 1019
>XP_006713105
          Length = 1545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 996  DVTRESF 1002
>XP_006713104
          Length = 1552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1003 DVTRESF 1009
>XP_006713103
          Length = 1553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1004 DVTRESF 1010
>XP_006713102
          Length = 1554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1005 DVTRESF 1011
>XP_006713101
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1012 DVTRESF 1018
>XP_006713100
          Length = 1561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1012 DVTRESF 1018
>XP_006713099
          Length = 1562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ELTRESF 9
            ++TRESF
Sbjct: 1013 DVTRESF 1019
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.119    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 449,261
Number of extensions: 950
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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