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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              18    1482
NP_001087241                                                           18    1482
XP_005265799                                                           18    1482
XP_005265798                                                           18    1482
XP_005265797                                                           18    1482
NP_001160022                                                           16    5631
NP_000193                                                              16    5631
NP_006114                                                              16    5631
NP_003844                                                              16    5631
NP_003817                                                              16    5631
XP_005264091                                                           16    5631
NP_659475                                                              16    7355
XP_005264694                                                           16    7355
NP_000055                                                              15    9605
NP_065868                                                              15    9605
NP_061187                                                              15    9605
XP_005247738                                                           15    9605
XP_005247737                                                           15    9605
XP_006713778                                                           15    9605

>NP_000213
          Length = 976

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           Q VQLIEKQ
Sbjct: 919 QIVQLIEKQ 927



>NP_001087241
          Length = 972

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           Q VQLIEKQ
Sbjct: 915 QIVQLIEKQ 923



>XP_005265799
          Length = 973

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           Q VQLIEKQ
Sbjct: 916 QIVQLIEKQ 924



>XP_005265798
          Length = 976

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           Q VQLIEKQ
Sbjct: 919 QIVQLIEKQ 927



>XP_005265797
          Length = 977

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           Q VQLIEKQ
Sbjct: 920 QIVQLIEKQ 928



>NP_001160022
          Length = 460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVQLIEK 8
           Q++QL+EK
Sbjct: 114 QAIQLLEK 121



>NP_000193
          Length = 550

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVQLIEK 8
           Q++QL+EK
Sbjct: 204 QAIQLLEK 211



>NP_006114
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVQLIEK 8
           Q++QL+EK
Sbjct: 204 QAIQLLEK 211



>NP_003844
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           QSVQL EK+
Sbjct: 348 QSVQLKEKR 356



>NP_003817
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QSVQLIEK 8
           ++VQLIEK
Sbjct: 93  EAVQLIEK 100



>XP_005264091
          Length = 457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           QSVQL EK+
Sbjct: 206 QSVQLKEKR 214



>NP_659475
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           Q VQ++E+Q
Sbjct: 293 QDVQILEQQ 301



>XP_005264694
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  QSVQLIEKQ 9
          Q VQ++E+Q
Sbjct: 87 QDVQILEQQ 95



>NP_000055
          Length = 1663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSVQLIEKQ 9
           +SVQL EK+
Sbjct: 671 RSVQLTEKR 679



>NP_065868
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QLIEKQ 9
           QLIEKQ
Sbjct: 561 QLIEKQ 566



>NP_061187
          Length = 1133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   QSVQLIEKQ 9
           Q  QLIE+Q
Sbjct: 742 QRAQLIEQQ 750



>XP_005247738
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QLIEKQ 9
           QLIEKQ
Sbjct: 240 QLIEKQ 245



>XP_005247737
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QLIEKQ 9
           QLIEKQ
Sbjct: 539 QLIEKQ 544



>XP_006713778
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   QLIEKQ 9
           QLIEKQ
Sbjct: 548 QLIEKQ 553



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.119    0.261 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,212
Number of extensions: 609
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)