Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001243398                                                           18    1135
NP_036462                                                              18    1135
NP_001243397                                                           18    1135
XP_005269721                                                           18    1135
NP_002215                                                              17    3301
XP_006715156                                                           17    3301
XP_006715155                                                           17    3301
XP_006715154                                                           17    3301
XP_006718995                                                           17    4312
XP_005274425                                                           17    4312
XP_006718994                                                           17    4312
XP_006718993                                                           17    4312
XP_005274424                                                           17    4312
XP_005274423                                                           17    4312
NP_203753                                                              17    4312
NP_001128661                                                           16    5631
XP_006712544                                                           16    5631
XP_006712543                                                           16    5631
XP_005246573                                                           16    5631
XP_006712542                                                           16    5631
XP_006712541                                                           16    5631
NP_001128660                                                           16    5631
NP_001128659                                                           16    5631
NP_004495                                                              16    5631
NP_001091982                                                           16    7355
NP_057063                                                              16    7355
NP_001123559                                                           16    7355
NP_001123558                                                           16    7355
NP_001123557                                                           16    7355
NP_001123556                                                           16    7355
NP_001123555                                                           16    7355
NP_001273617                                                           16    7355
NP_115808                                                              16    7355
NP_004821                                                              16    7355
NP_001257451                                                           16    7355
NP_001257450                                                           16    7355
XP_005267280                                                           16    7355
XP_005248088                                                           16    7355
XP_005248087                                                           16    7355
XP_005248086                                                           16    7355
XP_006713990                                                           16    7355
XP_005248085                                                           16    7355
XP_005248084                                                           16    7355
XP_005248083                                                           16    7355
XP_006713989                                                           16    7355
XP_005248082                                                           16    7355
XP_005248081                                                           16    7355
XP_005248080                                                           16    7355
XP_005248079                                                           16    7355
XP_006713988                                                           16    7355
XP_005248078                                                           16    7355
XP_005248077                                                           16    7355
XP_005248076                                                           16    7355
XP_006713987                                                           16    7355
XP_006713986                                                           16    7355
XP_005248075                                                           16    7355
XP_005248074                                                           16    7355
XP_005248073                                                           16    7355
XP_006713985                                                           16    7355
XP_005248072                                                           16    7355
XP_006713984                                                           16    7355
XP_005248071                                                           16    7355
NP_001123560                                                           16    7355
NP_004818                                                              15    9605
NP_001244315                                                           15    9605
NP_660305                                                              15    9605
NP_001138423                                                           15    9605
XP_005263413                                                           15    9605
XP_005263412                                                           15    9605
XP_005263411                                                           15    9605
XP_005264935                                                           15    9605
>NP_001243398
          Length = 1781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSVISVPSL 9
            QS ISVPSL
Sbjct: 1341 QSAISVPSL 1349
>NP_036462
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSVISVPSL 9
            QS ISVPSL
Sbjct: 1633 QSAISVPSL 1641
>NP_001243397
          Length = 1890

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSVISVPSL 9
            QS ISVPSL
Sbjct: 1450 QSAISVPSL 1458
>XP_005269721
          Length = 2073

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSVISVPSL 9
            QS ISVPSL
Sbjct: 1633 QSAISVPSL 1641
>NP_002215
          Length = 2671

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QSVISVPSL 9
           QSV S PSL
Sbjct: 933 QSVFSAPSL 941
>XP_006715156
          Length = 1341

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QSVISVPSL 9
           QSV S PSL
Sbjct: 962 QSVFSAPSL 970
>XP_006715155
          Length = 1850

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QSVISVPSL 9
           QSV S PSL
Sbjct: 962 QSVFSAPSL 970
>XP_006715154
          Length = 2700

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QSVISVPSL 9
           QSV S PSL
Sbjct: 962 QSVFSAPSL 970
>XP_006718995
          Length = 2382

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 406 SVISVPS 412
>XP_005274425
          Length = 2566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 639 SVISVPS 645
>XP_006718994
          Length = 2567

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 639 SVISVPS 645
>XP_006718993
          Length = 2602

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 626 SVISVPS 632
>XP_005274424
          Length = 2614

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 639 SVISVPS 645
>XP_005274423
          Length = 2615

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 639 SVISVPS 645
>NP_203753
          Length = 2601

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SVISVPS
Sbjct: 626 SVISVPS 632
>NP_001128661
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 319 SVVSVPS 325
>XP_006712544
          Length = 385

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 166 SVVSVPS 172
>XP_006712543
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 359 SVVSVPS 365
>XP_005246573
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>XP_006712542
          Length = 600

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>XP_006712541
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>NP_001128660
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 359 SVVSVPS 365
>NP_001128659
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 383 SVVSVPS 389
>NP_004495
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SVISVPS 8
           SV+SVPS
Sbjct: 359 SVVSVPS 365
>NP_001091982
          Length = 671

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  QSVISVPS 8
          QSV+ VPS
Sbjct: 44 QSVLPVPS 51
>NP_057063
          Length = 1365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    SVISVPSL 9
            SVIS PSL
Sbjct: 1176 SVISSPSL 1183
>NP_001123559
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_001123558
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_001123557
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_001123556
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_001123555
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_001273617
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QSVISVPS 8
          +S+ISVP+
Sbjct: 38 ESIISVPA 45
>NP_115808
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_004821
          Length = 1368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    SVISVPSL 9
            SVIS PSL
Sbjct: 1170 SVISSPSL 1177
>NP_001257451
          Length = 1364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    SVISVPSL 9
            SVIS PSL
Sbjct: 1170 SVISSPSL 1177
>NP_001257450
          Length = 1359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    SVISVPSL 9
            SVIS PSL
Sbjct: 1170 SVISSPSL 1177
>XP_005267280
          Length = 1374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    SVISVPSL 9
            SVIS PSL
Sbjct: 1176 SVISSPSL 1183
>XP_005248088
          Length = 475

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248087
          Length = 525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248086
          Length = 526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_006713990
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248085
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248084
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248083
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_006713989
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248082
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248081
          Length = 577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248080
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248079
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_006713988
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248078
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248077
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248076
          Length = 650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_006713987
          Length = 660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_006713986
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248075
          Length = 661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248074
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248073
          Length = 668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_006713985
          Length = 690

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248072
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>XP_006713984
          Length = 700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>XP_005248071
          Length = 701

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 286 ESIISVPA 293
>NP_001123560
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QSVISVPS 8
           +S+ISVP+
Sbjct: 281 ESIISVPA 288
>NP_004818
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSVISVPSL 9
           QSV+SV +L
Sbjct: 531 QSVVSVATL 539
>NP_001244315
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSVISVPSL 9
           QSV+SV +L
Sbjct: 531 QSVVSVATL 539
>NP_660305
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QSVISVP 7
           Q VISVP
Sbjct: 107 QGVISVP 113
>NP_001138423
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QSVISVP 7
           Q VISVP
Sbjct: 107 QGVISVP 113
>XP_005263413
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSVISVPSL 9
           QSV+SV +L
Sbjct: 529 QSVVSVATL 537
>XP_005263412
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSVISVPSL 9
           QSV+SV +L
Sbjct: 531 QSVVSVATL 539
>XP_005263411
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QSVISVPSL 9
           QSV+SV +L
Sbjct: 531 QSVVSVATL 539
>XP_005264935
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QSVISVP 7
           Q VISVP
Sbjct: 107 QGVISVP 113
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.122    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 677,721
Number of extensions: 826
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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