Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              18    1135
NP_001276793                                                           17    3301
NP_001276791                                                           17    3301
NP_001276790                                                           17    3301
NP_001276792                                                           17    3301
NP_058515                                                              17    3301
XP_005263586                                                           17    3301
XP_005263585                                                           17    3301
XP_005263584                                                           17    3301
XP_005263581                                                           17    3301
XP_005263580                                                           17    3301
XP_005263579                                                           17    3301
XP_005263578                                                           17    3301
NP_004127                                                              16    7355
NP_078815                                                              16    7355
NP_919445                                                              16    7355
NP_061184                                                              15    9605
NP_612393                                                              15    9605
NP_001273697                                                           15    9605
NP_113609                                                              15    9605
XP_006722192                                                           15    9605
>NP_004351
          Length = 882

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QSVEAGLQI 9
           Q VEAGLQI
Sbjct: 699 QPVEAGLQI 707
>NP_001276793
          Length = 890

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 272 QALQAGLQI 280
>NP_001276791
          Length = 1210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 591 QALQAGLQI 599
>NP_001276790
          Length = 1191

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 591 QALQAGLQI 599
>NP_001276792
          Length = 1184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 584 QALQAGLQI 592
>NP_058515
          Length = 1201

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 583 QALQAGLQI 591
>XP_005263586
          Length = 1036

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 416 QALQAGLQI 424
>XP_005263585
          Length = 1094

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 474 QALQAGLQI 482
>XP_005263584
          Length = 1095

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 475 QALQAGLQI 483
>XP_005263581
          Length = 1203

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 591 QALQAGLQI 599
>XP_005263580
          Length = 1204

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 584 QALQAGLQI 592
>XP_005263579
          Length = 1210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 590 QALQAGLQI 598
>XP_005263578
          Length = 1210

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           Q+++AGLQI
Sbjct: 591 QALQAGLQI 599
>NP_004127
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSVEAGLQI 9
           ++VEAGL++
Sbjct: 530 KAVEAGLRV 538
>NP_078815
          Length = 402

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QSVEAGLQI 9
           QS++ G+Q+
Sbjct: 155 QSIQRGIQV 163
>NP_919445
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QSVEAGLQI 9
           QS++ G+Q+
Sbjct: 181 QSIQRGIQV 189
>NP_061184
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QSVEAGLQ 8
           QS+E G+Q
Sbjct: 590 QSIEEGVQ 597
>NP_612393
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QSVEAGLQI 9
           +SVE GL++
Sbjct: 212 ESVETGLKL 220
>NP_001273697
          Length = 225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VEAGLQI 9
           VE GLQI
Sbjct: 216 VEVGLQI 222
>NP_113609
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSVEAG 6
           QSVEAG
Sbjct: 567 QSVEAG 572
>XP_006722192
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   QSVEAG 6
           QSVEAG
Sbjct: 404 QSVEAG 409
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.125    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 363,558
Number of extensions: 271
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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