Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              22     134
XP_005273257                                                           22     134
NP_001243779                                                           18    1135
NP_596869                                                              18    1135
XP_006712787                                                           18    1135
XP_006712786                                                           18    1135
NP_001254479                                                           18    1135
NP_005920                                                              17    2528
NP_201573                                                              17    2528
XP_006713707                                                           17    2528
XP_006713706                                                           17    2528
XP_006713705                                                           17    2528
NP_006047                                                              17    4312
NP_689831                                                              16    5631
NP_689998                                                              16    5631
NP_001171478                                                           16    5631
NP_001177188                                                           16    5631
NP_001177189                                                           16    5631
NP_149114                                                              16    5631
XP_005253583                                                           16    5631
XP_005253581                                                           16    5631
XP_005253580                                                           16    5631
XP_006719225                                                           16    5631
XP_005253579                                                           16    5631
XP_005253578                                                           16    5631
XP_005253577                                                           16    5631
XP_005253576                                                           16    5631
XP_005247329                                                           16    5631
XP_005247328                                                           16    5631
NP_004988                                                              16    7355
NP_612152                                                              16    7355
NP_955452                                                              16    7355
XP_006713543                                                           16    7355
XP_005245254                                                           16    7355
XP_005245253                                                           16    7355
NP_006320                                                              15    9605
NP_872604                                                              15    9605
NP_003830                                                              15    9605
NP_001265197                                                           15    9605
NP_001138626                                                           15    9605
NP_004590                                                              15    9605
NP_001364                                                              15    9605
NP_063941                                                              15    9605
NP_003599                                                              15    9605
NP_055641                                                              15    9605
NP_659426                                                              15    9605
NP_003598                                                              15    9605
XP_006724373                                                           15    9605
XP_005266834                                                           15    9605
XP_005267324                                                           15    9605
XP_005273381                                                           15    9605
XP_005273380                                                           15    9605
XP_005273379                                                           15    9605
XP_006711899                                                           15    9605
XP_005273378                                                           15    9605
XP_005273377                                                           15    9605
XP_006711898                                                           15    9605
XP_006711897                                                           15    9605
XP_005273375                                                           15    9605
XP_005273374                                                           15    9605
XP_006711798                                                           15    9605
NP_872605                                                              15    9605
>NP_064450
          Length = 1722

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QSTFSES+C
Sbjct: 1457 QSTFSESIC 1465
>XP_005273257
          Length = 1726

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QSTFSES+C
Sbjct: 1461 QSTFSESIC 1469
>NP_001243779
          Length = 34350

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QS+FSE++C
Sbjct: 7715 QSSFSENVC 7723

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            Q+TFS+++C
Sbjct: 6774 QTTFSDNVC 6782
>NP_596869
          Length = 33423

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QS+FSE++C
Sbjct: 6788 QSSFSENVC 6796

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            Q+TFS+++C
Sbjct: 5847 QTTFSDNVC 5855
>XP_006712787
          Length = 33978

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QS+FSE++C
Sbjct: 7716 QSSFSENVC 7724

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            Q+TFS+++C
Sbjct: 6775 QTTFSDNVC 6783
>XP_006712786
          Length = 35484

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QS+FSE++C
Sbjct: 7716 QSSFSENVC 7724

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            Q+TFS+++C
Sbjct: 6775 QTTFSDNVC 6783
>NP_001254479
          Length = 35991

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            QS+FSE++C
Sbjct: 8032 QSSFSENVC 8040

 Score = 17.7 bits (34), Expect =  1935
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QSTFSESLC 9
            Q+TFS+++C
Sbjct: 7091 QTTFSDNVC 7099
>NP_005920
          Length = 738

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSTFSESLC 9
           ++++SESLC
Sbjct: 178 ETSYSESLC 186
>NP_201573
          Length = 302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSTFSESLC 9
           ++++SESLC
Sbjct: 178 ETSYSESLC 186
>XP_006713707
          Length = 746

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSTFSESLC 9
           ++++SESLC
Sbjct: 178 ETSYSESLC 186
>XP_006713706
          Length = 759

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSTFSESLC 9
           ++++SESLC
Sbjct: 178 ETSYSESLC 186
>XP_006713705
          Length = 760

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QSTFSESLC 9
           ++++SESLC
Sbjct: 178 ETSYSESLC 186
>NP_006047
          Length = 426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSTFSESLC 9
           + TF E+LC
Sbjct: 364 RETFQEALC 372
>NP_689831
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFSESLC 9
           TFS SLC
Sbjct: 152 TFSVSLC 158
>NP_689998
          Length = 178

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TFSESLC 9
          T+SE LC
Sbjct: 79 TYSEELC 85
>NP_001171478
          Length = 710

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFSESLC 9
           TFS SLC
Sbjct: 152 TFSVSLC 158
>NP_001177188
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TFSESLC 9
          T+SE LC
Sbjct: 81 TYSEELC 87
>NP_001177189
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TFSESLC 9
          T+SE LC
Sbjct: 64 TYSEELC 70
>NP_149114
          Length = 608

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 265 QATFGESL 272
>XP_005253583
          Length = 545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 161 QATFGESL 168
>XP_005253581
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 137 QATFGESL 144
>XP_005253580
          Length = 545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 161 QATFGESL 168
>XP_006719225
          Length = 545

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 161 QATFGESL 168
>XP_005253579
          Length = 610

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 265 QATFGESL 272
>XP_005253578
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 265 QATFGESL 272
>XP_005253577
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 265 QATFGESL 272
>XP_005253576
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QSTFSESL 8
           Q+TF ESL
Sbjct: 265 QATFGESL 272
>XP_005247329
          Length = 161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TFSESLC 9
          T+SE LC
Sbjct: 62 TYSEELC 68
>XP_005247328
          Length = 165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TFSESLC 9
          T+SE LC
Sbjct: 66 TYSEELC 72
>NP_004988
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FSESLC 9
           FSE+LC
Sbjct: 341 FSENLC 346
>NP_612152
          Length = 2849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    FSESLC 9
            F+ESLC
Sbjct: 2205 FTESLC 2210
>NP_955452
          Length = 2590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    FSESLC 9
            FS+SLC
Sbjct: 1522 FSDSLC 1527
>XP_006713543
          Length = 2591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    FSESLC 9
            FS+SLC
Sbjct: 1523 FSDSLC 1528
>XP_005245254
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FSESLC 9
           FSE+LC
Sbjct: 179 FSENLC 184
>XP_005245253
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FSESLC 9
           FSE+LC
Sbjct: 341 FSENLC 346
>NP_006320
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSTFSESLC 9
           + +FSE LC
Sbjct: 250 ECSFSEFLC 258
>NP_872604
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TFSESLC 9
           TFS+++C
Sbjct: 190 TFSQNVC 196
>NP_003830
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   QSTFSESLC 9
           + TF E +C
Sbjct: 292 EKTFPEDMC 300
>NP_001265197
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   QSTFSESLC 9
           + TF E +C
Sbjct: 278 EKTFPEDMC 286
>NP_001138626
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TFSESL 8
          TFSESL
Sbjct: 61 TFSESL 66
>NP_004590
          Length = 1141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  FSESLC 9
          FSE LC
Sbjct: 46 FSEQLC 51
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TFSESL 8
          TFSESL
Sbjct: 61 TFSESL 66
>NP_063941
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSTFSESLC 9
           ++TF E LC
Sbjct: 307 RNTFREILC 315
>NP_003599
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TFSESLC 9
          TFS +LC
Sbjct: 81 TFSPALC 87
>NP_055641
          Length = 1638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1274 FSEQLC 1279
>NP_659426
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TFSESL 8
          TFSESL
Sbjct: 61 TFSESL 66
>NP_003598
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1355 FSEQLC 1360
>XP_006724373
          Length = 1111

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  FSESLC 9
          FSE LC
Sbjct: 16 FSEQLC 21
>XP_005266834
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   QSTFSESLC 9
           + TF E +C
Sbjct: 292 EKTFPEDMC 300
>XP_005267324
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSTFSESLC 9
           + +FSE LC
Sbjct: 267 ECSFSEFLC 275
>XP_005273381
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1368 FSEQLC 1373
>XP_005273380
          Length = 1751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1325 FSEQLC 1330
>XP_005273379
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1390 FSEQLC 1395
>XP_006711899
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1406 FSEQLC 1411
>XP_005273378
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1355 FSEQLC 1360
>XP_005273377
          Length = 1794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1368 FSEQLC 1373
>XP_006711898
          Length = 1797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1371 FSEQLC 1376
>XP_006711897
          Length = 1816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1390 FSEQLC 1395
>XP_005273375
          Length = 1829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1403 FSEQLC 1408
>XP_005273374
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4    FSESLC 9
            FSE LC
Sbjct: 1406 FSEQLC 1411
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TFSESL 8
          TFSESL
Sbjct: 61 TFSESL 66
>NP_872605
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   TFSESLC 9
           TFS+++C
Sbjct: 190 TFSQNVC 196
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.115    0.326 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 502,059
Number of extensions: 972
Number of successful extensions: 67
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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