Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     299
NP_065071                                                              16    5631
NP_076968                                                              16    5631
NP_872363                                                              16    5631
XP_005271570                                                           16    5631
XP_005271569                                                           16    5631
XP_006718878                                                           16    5631
XP_005271568                                                           16    5631
XP_006717988                                                           16    5631
XP_006717987                                                           16    5631
XP_006717986                                                           16    5631
XP_005270044                                                           16    5631
XP_005270045                                                           16    5631
NP_001008781                                                           16    7355
YP_003024036                                                           16    7355
NP_056175                                                              15    9605
NP_001186804                                                           15    9605
NP_008923                                                              15    9605
NP_964013                                                              15    9605
NP_001073918                                                           15    9605
XP_005262121                                                           15    9605
XP_006717743                                                           15    9605
NP_443168                                                              15    9605
NP_001128689                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QSRMGINQP 9
            QSR GINQP
Sbjct: 1071 QSRTGINQP 1079
>NP_065071
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           MG+NQP
Sbjct: 365 MGMNQP 370
>NP_076968
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   RMGINQP 9
           RMG+ QP
Sbjct: 492 RMGLTQP 498
>NP_872363
          Length = 1499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QSRMGINQP 9
            QS MG+N P
Sbjct: 1153 QSPMGMNLP 1161
>XP_005271570
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QSRMGINQP 9
            QS MG+N P
Sbjct: 1116 QSPMGMNLP 1124
>XP_005271569
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QSRMGINQP 9
            QS MG+N P
Sbjct: 1116 QSPMGMNLP 1124
>XP_006718878
          Length = 1499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QSRMGINQP 9
            QS MG+N P
Sbjct: 1153 QSPMGMNLP 1161
>XP_005271568
          Length = 1499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    QSRMGINQP 9
            QS MG+N P
Sbjct: 1153 QSPMGMNLP 1161
>XP_006717988
          Length = 986

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           MG+NQP
Sbjct: 371 MGMNQP 376
>XP_006717987
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           MG+NQP
Sbjct: 371 MGMNQP 376
>XP_006717986
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           MG+NQP
Sbjct: 371 MGMNQP 376
>XP_005270044
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           MG+NQP
Sbjct: 371 MGMNQP 376
>XP_005270045
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           MG+NQP
Sbjct: 371 MGMNQP 376
>NP_001008781
          Length = 4557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  QSRMGI 6
          QSRMGI
Sbjct: 65 QSRMGI 70
>YP_003024036
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MGINQP 9
           +GINQP
Sbjct: 317 IGINQP 322
>NP_056175
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   MGINQP 9
           MGIN P
Sbjct: 487 MGINMP 492
>NP_001186804
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  QSRMGINQP 9
          + R+G+ QP
Sbjct: 37 KQRVGVQQP 45
>NP_008923
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSRMGINQP 9
           +S +GIN P
Sbjct: 192 ESTLGINLP 200
>NP_964013
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSRMGINQP 9
           +S +GIN P
Sbjct: 192 ESTLGINLP 200
>NP_001073918
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   MGINQP 9
           MGIN P
Sbjct: 744 MGINHP 749
>XP_005262121
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RMGINQ 8
           R+GINQ
Sbjct: 153 RLGINQ 158
>XP_006717743
          Length = 1090

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   MGINQP 9
           MGIN P
Sbjct: 774 MGINHP 779
>NP_443168
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   RMGINQ 8
           R+GINQ
Sbjct: 230 RLGINQ 235
>NP_001128689
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   QSRMGINQP 9
           +S +GIN P
Sbjct: 192 ESTLGINLP 200
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.128    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,255
Number of extensions: 579
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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